Used 2021 Mercedes-Benz S-Class for Sale near Washington, DC
176 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 173 currently listed for sale near Washington, DC and an average price of $64,200.00, 17.3% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
88.4% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class showcases advanced technology, luxurious interior fittings, and powerful engine options, making it a standout in the full-size luxury sedan market.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 173 currently listed for sale near Washington, DC and an average price of $64,200.00, 17.3% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
88.4% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class showcases advanced technology, luxurious interior fittings, and powerful engine options, making it a standout in the full-size luxury sedan market.
Why it stands out
The 2021 Mercedes-Benz S-Class stands out as a pinnacle of luxury, technology, and performance in the full-size sedan segment. This model boasts a complete redesign that includes significant technological enhancements, including a cutting-edge infotainment system and advanced powertrains. The S-Class is offered in two configurations — the S500 with a turbocharged inline-six engine producing 429 horsepower and the S580 equipped with a powerful V8 engine generating 496 horsepower. Both models benefit from 4Matic all-wheel-drive and a mild-hybrid EQ Boost system for improved efficiency and performance. The interior is meticulously crafted with high-end materials, offering a minimalist design that emphasizes a user-friendly digital experience. Moreover, the inclusion of innovative safety features and driver assistance technologies ensures a secure and comfortable ride. While it comes with a luxury price tag, the breadth of features and the level of refinement make the 2021 Mercedes-Benz S-Class a compelling choice for buyers seeking the ultimate driving experience.
Other model years to consider
- Average price: $24,187.00
- Good/great deal percentage: 23.2%
- User rating: 5 / 5
- Total listings: 267
- Average price: $31,851.00
- Good/great deal percentage: 20.7%
- User rating: 4.9 / 5
- Total listings: 241
- Average price: $26,089.00
- Good/great deal percentage: 21.5%
- User rating: 5 / 5
- Total listings: 200
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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