Used 2021 Mercedes-Benz E-Class for Sale near Memphis, TN
126 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 849 currently listed for sale and an average price of $38,993.00, 34.4% of 2021 Mercedes-Benz E-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.3% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class is known for its elegant design, powerful engine options, and advanced technology features.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 849 currently listed for sale and an average price of $38,993.00, 34.4% of 2021 Mercedes-Benz E-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.3% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class is known for its elegant design, powerful engine options, and advanced technology features.
Why it stands out
The 2021 Mercedes-Benz E-Class distinguishes itself as a midsize luxury sedan that perfectly balances performance, comfort, and cutting-edge technology. With an impressive lineup of four body styles and multiple powertrains, including the new electrified inline-six engines, it caters to a wide range of luxury car enthusiasts. The interior is exceptionally crafted, offering lavish materials and innovative tech like the MBUX infotainment system. Despite some criticisms regarding the absence of advanced safety features as standard, the E-Class shines with a high-quality ride, great handling, and safety ratings that speak volumes about its reliability. Modest updates for 2021 include enhancements to the infotainment system and subtle exterior styling tweaks, reinforcing its status as a sophisticated choice among luxury sedans.
Other model years to consider
- Average price: $30,066.00
- Good/great deal percentage: 35.5%
- User rating: 5 / 5
- Total listings: 976
- Average price: $23,881.00
- Good/great deal percentage: 35.3%
- User rating: 4.76 / 5
- Total listings: 1,404
- Average price: $41,476.00
- Good/great deal percentage: 32.4%
- User rating: 5 / 5
- Total listings: 1,062
This analysis is based on CarGurus' proprietary market data from May 18, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| AMG E 53 Cabriolet 4MATIC | $82,850 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
See more price trends
