Used 2021 Lexus RX for Sale near District of Columbia
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,100
- Stock #:
- OS279028
- VIN:
- 2T2HZMDA8MC279028


Sponsored by Safford Subaru Manassas
2021 Lexus RX
350 AWD
61,100 mi
$33,898
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 100,117
- Stock #:
- 620503B
- VIN:
- 2T2HZMDA5LC219495

Sponsored Listing
2020 Lexus RX
350 AWD
100,117 mi
$30,399
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 89,401
- Stock #:
- KTGSLC248168
- VIN:
- 2T2HZMDA3LC248168

Sponsored Listing
2020 Lexus RX
350 AWD
89,401 mi
$29,495
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- Automatic
- Mileage:
- 63,084
- Stock #:
- HT772A
- VIN:
- JTJHZMDA5M2053139

2021 Lexus RX
350 AWD
63,084 mi
$35,779
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 40,332
- Stock #:
- T66222A
- VIN:
- 2T2HZMDA2MC305462

2021 Lexus RX
350 AWD
40,332 mi
$39,794
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 69,234
- Stock #:
- C1634
- VIN:
- JTJHZKFA7M2028373

2021 Lexus RX
350L AWD
69,234 mi
$34,500
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,524
- Stock #:
- N1Y0004
- VIN:
- 2T2AZMDA6NC316306

2022 Lexus RX
350 AWD
45,524 mi
$39,689
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,852
- Stock #:
- PNC337161
- VIN:
- 2T2SZMDA6NC337161

2022 Lexus RX
350 F Sport AWD
46,852 mi
$39,610
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 24,943
- Stock #:
- 171108
- VIN:
- JTJHZMDA6M2053473

2021 Lexus RX
350 AWD
24,943 mi
$39,490
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 71,755
- Stock #:
- KFCPLC235189
- VIN:
- 2T2HZMDA1LC235189

2020 Lexus RX
350 AWD
71,755 mi
$32,745
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 56,436
- Stock #:
- PLC220592
- VIN:
- 2T2HZMDA8LC220592

2020 Lexus RX
350 AWD
56,436 mi
$35,774
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,940
- Stock #:
- 240819
- VIN:
- 2T2HZMDA0LC240819

2020 Lexus RX
350 AWD
52,940 mi
$33,585
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 43,002
- Stock #:
- TC306413
- VIN:
- 2T2HZMDA5MC306413

2021 Lexus RX
350 AWD
43,002 mi
$37,797
CarGurus Analysis:
2021 Lexus RX
With 1,459 currently listed for sale and an average price of $35,863.00, 34.3% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
75.1% of 2021 RX models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,255
- Stock #:
- KMBTN2038551
- VIN:
- JTJHZKFA9N2038551

2022 Lexus RX
350L AWD
59,255 mi
$39,800
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,837
- Stock #:
- 3U024445
- VIN:
- JTJHZKFAXL2024445

2020 Lexus RX
350L AWD
46,837 mi
$37,297
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,100
- Stock #:
- OS279028
- VIN:
- 2T2HZMDA8MC279028

2021 Lexus RX
350 AWD
61,100 mi
$33,898
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 104,655
- Stock #:
- K28674A
- VIN:
- 2T2HZMDA0LC218951

2020 Lexus RX
350 AWD
104,655 mi
$27,770
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 38,131
- Stock #:
- KFCPMC190637
- VIN:
- 2T2AZMAA7MC190637

2021 Lexus RX
350 FWD
38,131 mi
$38,245
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 94,093
- Stock #:
- 62F0110A
- VIN:
- 2T2HZMDAXLC226717

2020 Lexus RX
350 AWD
94,093 mi
$29,022
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 100,117
- Stock #:
- 620503B
- VIN:
- 2T2HZMDA5LC219495

2020 Lexus RX
350 AWD
100,117 mi
$30,399
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 70,532
- Stock #:
- 1248P
- VIN:
- 2T2HZMDA3MC275226

2021 Lexus RX
350 AWD
70,532 mi
$34,484
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,740
- Stock #:
- 70222396
- VIN:
- 2T2SZMDA8LC216466

2020 Lexus RX
350 F Sport AWD
59,740 mi
$35,897
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 38,131
- Stock #:
- KFCPMC190637
- VIN:
- 2T2AZMAA7MC190637

Sponsored Listing
2021 Lexus RX
350 FWD
38,131 mi
$38,245
CarGurus Analysis: 2021 Lexus RX
overall

Summary
With 1,459 currently listed for sale and an average price of $35,863.00, 34.3% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
75.1% of 2021 RX models on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX continues to make a strong case for itself as one of America’s favorite luxury SUVs. For this model year, the body and mechanics are mostly unchanged, but it still stands out for comfortable accommodations, plenty of creature comforts, and Lexus’ long-standing reputation for reliability. It also brings a few tech upgrades for 2021, including new standard safety systems.
What makes the 2021 Lexus RX appealing is the way it balances comfort and value. Its ride quality is a clear strength, and the cabin is designed to be comfortable for everyday use. At the same time, it remains an excellent value for money in the luxury SUV class. The tradeoff is that performance is fairly pedestrian, and the technology can be unintuitive, so buyers who prioritize quick acceleration or a more seamless interface may find it less satisfying.
Other model years to consider
- Average price: $46,268.00
- Good/great deal percentage: 35.4%
- User rating: 5 / 5
- Total listings: 3,050
- Average price: $49,657.00
- Good/great deal percentage: 35.4%
- User rating: 5 / 5
- Total listings: 3,037
- Average price: $33,437.00
- Good/great deal percentage: 35.2%
- User rating: 4.88 / 5
- Total listings: 1,257
This analysis is based on CarGurus' proprietary market data from August 31, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury AWD | $55,450 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport AWD | $50,100 |
| 350 F Sport Handling AWD | $52,500 |
| 350 AWD | $46,620 |
| 350 FWD | $45,220 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
See more price trends2021 Lexus RX Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Chicago: The city commands the highest average price at $36,343, likely due to higher demand and lower inventory.
- Lowest Prices in Miami: With an average price of $31,941, Miami offers the best value, suggesting a more competitive market or higher inventory levels.
- Inventory Variation: Cities like Dallas (126 listings) and Houston (138 listings) show a balance of inventory and pricing, with average prices around $36,483 and $35,435, respectively.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Chicago, IL | 109 | $36,343 |
| Dallas, TX | 126 | $36,483 |
| Houston, TX | 138 | $35,435 |
| Philadelphia, PA | 100 | $35,674 |
| New York, NY | 162 | $35,123 |
| Los Angeles, CA | 118 | $33,982 |
| Atlanta, GA | 147 | $34,965 |
| Boston, MA | 98 | $34,515 |
| Washington, DC | 135 | $35,353 |
| Miami, FL | 103 | $31,941 |
Pricing by Trim Packages
Key Insights
- FWD vs. AWD Demand: The 350 FWD trim leads in inventory with 2,268 listings, indicating a strong preference for front-wheel drive in the market.
- Premium Pricing for AWD Trims: The 350L Luxury FWD trim, priced at $54,050 MSRP, reflects the highest price point, catering to buyers seeking luxury features.
- Balanced Inventory Across Trims: The 350 AWD trim has a significant presence with 2,005 listings, suggesting a healthy demand for all-wheel drive options.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 350 FWD | 2268 | $45,220 | FWD | 3.5L 295 hp V6 |
| 350 AWD | 2005 | $46,620 | AWD | 3.5L 295 hp V6 |
| 350 F Sport AWD | 420 | $50,100 | AWD | 3.5L 295 hp V6 |
| 350 F Sport Handling AWD | 420 | $52,500 | AWD | 3.5L 295 hp V6 |
| 350L AWD | 151 | $49,450 | AWD | 3.5L 290 hp V6 |
| 350L FWD | 118 | $48,050 | FWD | 3.5L 290 hp V6 |
| 350 F Sport FWD | 98 | $48,700 | FWD | 3.5L 295 hp V6 |
| 350L Luxury FWD | 20 | $54,050 | FWD | 3.5L 290 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models at a Premium: The 2026 Lexus RX is priced at $63,229, reflecting a 23.4% increase over its MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2014 Lexus RX shows the steepest decline, with an average price of $15,682, representing a 60.6% drop from its original MSRP.
- Best Value in Recent Years: The 2022 Lexus RX is priced at $39,252, which is 14.5% below MSRP, making it an attractive option for buyers looking for a balance of price and features.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $51,225 | $63,229 | +23.4% |
| 2025 | $48,975 | $53,502 | +9.3% |
| 2024 | $48,600 | $49,422 | +1.7% |
| 2023 | $47,800 | $45,936 | -3.9% |
| 2022 | $45,920 | $39,252 | -14.5% |
| 2020 | $44,150 | $33,651 | -23.8% |
| 2019 | $43,820 | $29,728 | -32.2% |
| 2018 | $43,470 | $27,439 | -36.8% |
| 2017 | $43,220 | $24,859 | -42.5% |
| 2016 | $41,900 | $22,513 | -46.3% |
| 2015 | $40,970 | $17,746 | -56.7% |
| 2014 | $39,760 | $15,682 | -60.6% |
These recommendations are based on CarGurus' proprietary market data from September 3, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus RX cost?
| Metric | Value |
|---|---|
| Current Average Price | $35,754 |
| Year-Round Low | $35,275.26 |
| Year-Round High | $36,734.59 |
| Average Price a Year Ago | $36,630 |
| Change vs. Last Year | −2.39% |
Prices have softened 2.39% compared to this time last year, making it a favorable time to shop this model year.
There are 1,502 listings available, which gives you a meaningful pool to compare before you commit.
If you find a listing below $35,275.26, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Lexus RX a good car?
Yes — the 2021 Lexus RX earns a 4.92/5 user rating and a 7.83/10 expert rating. The standout strength is Cost effectiveness at 9/10.
Owners consistently praise its reliability, luxurious features, and smooth driving experience. Comfort and handling also come up often as positives, which fits a luxury SUV that’s built around everyday ease rather than drama.
The trade-offs are familiar: performance is fairly pedestrian, and the technology can feel unintuitive. That matters most if you want quick acceleration or a more seamless interface.
For you, that means the RX makes the most sense if you want a comfortable, value-minded luxury SUV for commuting and daily use rather than a sporty crossover.
With 34.7% of listings marked as good or great deals, there’s enough market activity to shop selectively.
Is the 2021 Lexus RX reliable?
Owners rate it 4.92/5, a strong signal of long-term satisfaction.
The owner feedback repeatedly points to reliability and a trouble-free ownership experience, alongside the RX’s smooth driving character and luxury feel. That lines up with the model’s reputation for dependable long-term use.
It also helps that Lexus builds the RX around a proven V6 setup and a smooth automatic transmission, which supports the sense that this is a vehicle you can count on. Lexus also includes a first scheduled maintenance visit on the house.
For used buyers, the main long-term risk is less about outright durability and more about buying a neglected example, so service history and condition matter a lot.
What should I look for when buying a used 2021 Lexus RX?
Accident-free inventory is solid at 75.2% — always verify the vehicle history report.
You should still run a history report on any RX you’re considering, because accident-free status is only a starting point. Prioritize a pre-purchase inspection if the vehicle has higher mileage, incomplete records, or signs of cosmetic repair. Focus on cabin condition, infotainment usability, and how well the vehicle has been maintained, since those are the areas that most affect day-to-day satisfaction.
Key things to evaluate:
- Trim level: The base RX comes with standard 18-inch wheels, LED lighting, rear privacy glass, and a nicely appointed cabin with NuLuxe-trimmed seats and power-adjustable front seats. Higher variants add features such as a longer body, a third row, or more performance-focused appearance and suspension equipment, so base-trim shoppers should check carefully for the comfort and convenience items they want.
- Powertrain: The standard setup uses a 3.5-liter V6 with 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic. Hybrid versions use the same V6 with three electric motors and an e-CVT, and they are the efficiency-focused choice.
- Safety package: Lexus Safety System+ 2.0 is standard and includes pre-collision warning, automatic emergency braking, pedestrian and cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. Every RX also gets a rearview camera, 10 airbags, stability control, and blind-spot monitoring with rear cross-traffic alert.
- Infotainment: Standard equipment includes an 8-inch touchscreen, Bluetooth, Apple CarPlay, Android Auto, Amazon Alexa, satellite radio, HD Radio, a WiFi hot spot, six USB ports, and a nine-speaker sound system. A 12.3-inch screen, navigation, wireless charging, and upgraded audio are available, but wireless Apple CarPlay and Android Auto are not.
- Fuel efficiency: The front-wheel-drive RX 350 returns 20 mpg in the city, 27 mpg on the highway, and 23 mpg combined. AWD and the longer body reduce combined efficiency, while the hybrid models are rated at 29 or 31 mpg in the city and 28 mpg on the highway.
Which 2021 Lexus RX trim should I buy?
The 2021 Lexus RX is offered in 5 trim levels: RX, RX F Sport, RXL, RX Hybrid, and RXL Hybrid.
Here's the short version:
- RX: This is the standard two-row choice and the best fit if you want the core RX experience with the least complexity. It gives you the comfort, luxury feel, and standard safety tech that define the model, making it the best-value trim for most shoppers.
- RX F Sport: Choose this if you want the most driver-focused version of the RX. It adds a more aggressive appearance and sport-oriented hardware, but it still stays true to the RX’s comfort-first personality.
- RXL: Pick this if you want the extended body and the available third row. It’s the practical choice for buyers who need more passenger flexibility than the standard RX provides.
- RX Hybrid: This is the efficiency-minded version of the standard two-row RX. It suits you if you want the RX’s comfort and equipment with better fuel economy.
- RXL Hybrid: This is the most family-oriented option if you want the longer body, third row, and hybrid efficiency in one package.
The safety suite is standard across the lineup, but the longer-body RXL and RXL Hybrid were not tested by IIHS.
Is now a good time to buy a used 2021 Lexus RX?
This is a moderate, selective buyer’s market, so you can shop carefully without feeling rushed.
- Deal availability: 34.7% of listings are priced as good or great deals.
- Inventory: There are 1,502 listings available.
- Price trend: Prices have softened 2.39% compared with last year.
- Clean inventory: 75.2% of listings are accident-free.
If you find a listing below $35,275.26, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus RX's resale value?
The current average of $35,754 sits slightly below last year's $36,630.
That kind of price movement suggests the RX has softened a bit in the used market, which can help you buy more confidently now. For a future seller, it also means you should expect resale value to depend heavily on condition, mileage, and how well the vehicle has been maintained.
Because the RX has broad appeal and strong owner satisfaction, it should remain relatively easy to move compared with less established luxury SUVs. The key is to buy a clean example now so you preserve as much value as possible later.
Vehicles with strong owner satisfaction ratings, like this model year's 4.92/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus RX safe?
The 2021 Lexus RX earns a Top Safety Pick designation from IIHS and four-star ratings overall from NHTSA, with five-star ratings in side-impact crashworthiness.
It earns a 8/10 safety score from our experts.
Every RX comes standard with Lexus Safety System+ 2.0, which includes pre-collision warning, automatic emergency braking, pedestrian detection, cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. You also get a rearview camera, 10 airbags, stability control, and blind-spot monitoring with rear cross-traffic alert.
The main caveat is that the longer RXL and RXL Hybrid versions were not tested by IIHS, so you should pay close attention to the exact body style you’re considering. The RX’s safety tech is strong, but it doesn’t offer the most advanced hands-off driving assistance in the class.
Should I buy a 2021 Lexus RX or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 34.7% of listings are priced as good or great deals.
- Accident-free inventory is solid at 75.2% — always verify the vehicle history report.
- Price trend: Prices have softened 2.39% compared with last year.
- Owners rate it 4.92/5 — a strong satisfaction signal.
- It adds new standard safety systems while keeping the RX’s comfort-first formula.
Consider the 2020 if:
- At $33,361, the 2020 costs less than the current year's $35,754 average.
- It emphasizes comfort, refinement, and everyday usability.
Consider the 2022 if:
- At $39,570, the 2022 costs more than the current year's $35,754 average.
- It brings minimal changes, including new colors and a standalone fog lamps option.
The bottom line: If you want the best balance of price, safety updates, and broad availability, the 2021 is the smart default. If your budget is tighter, the 2020 is the better value play, while the 2022 makes sense only if you specifically want the newer model year and don’t mind paying more.
These recommendations are based on CarGurus' proprietary market data from September 4, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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