Used 2021 Lexus IS for Sale nearWorcester, MA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 48,244
- Stock #:
- AB7962
- VIN:
- JTHGZ1E26M5021754


Sponsored by Autobahn USA
2021 Lexus IS
350 F Sport AWD
48,244 mi
$39,394
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 47,341
- Stock #:
- U1500469A
- VIN:
- JTHC81F22M5043329

Sponsored Listing
2021 Lexus IS
300 AWD
47,341 mi
$33,522
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 53,702
- Stock #:
- 1701026A
- VIN:
- JTHD81F24N5047677

Sponsored Listing
2022 Lexus IS
300 AWD
53,702 mi
$34,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red (BURGUNDY)
- Transmission:
- Automatic
- Mileage:
- 62,061
- Stock #:
- 70302191
- VIN:
- JTHCA1D22M5113676

2021 Lexus IS
300 RWD
62,061 mi
$30,997
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 47,341
- Stock #:
- U1500469A
- VIN:
- JTHC81F22M5043329

2021 Lexus IS
300 AWD
47,341 mi
$33,522
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 48,244
- Stock #:
- AB7962
- VIN:
- JTHGZ1E26M5021754

2021 Lexus IS
350 F Sport AWD
48,244 mi
$39,394
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 74,683
- Stock #:
- 26993O
- VIN:
- JTHGZ1E23M5019251

2021 Lexus IS
350 F Sport AWD
74,683 mi
$33,398
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- White
- Interior color:
- Black W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 12,620
- Stock #:
- CT8872A
- VIN:
- JTHGZ1E23N5026430

2022 Lexus IS
350 F SPORT 2 AWD
12,620 mi
$44,697
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 94,279
- Stock #:
- 11-9383
- VIN:
- JTHGZ1E28N5026066

2022 Lexus IS
350 F SPORT AWD
94,279 mi
$31,596
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- White
- Interior color:
- Gray
- Transmission:
- 6-Speed Automatic
- Mileage:
- 86,730
- Stock #:
- 9102
- VIN:
- JTHGZ1E22N5025754

2022 Lexus IS
350 F SPORT 2 AWD
86,730 mi
$33,995
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 53,702
- Stock #:
- 1701026A
- VIN:
- JTHD81F24N5047677

2022 Lexus IS
300 AWD
53,702 mi
$34,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,431
- Stock #:
- NV044071
- VIN:
- JTHGZ1B2XM5044071

2021 Lexus IS
350 F Sport RWD
64,431 mi
$33,628
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,101
- Stock #:
- 30516
- VIN:
- JTHGZ1B25M5042471

2021 Lexus IS
350 F Sport RWD
62,101 mi
$37,501
CarGurus Analysis:
2021 Lexus IS
With 60 currently listed for sale and an average price of $33,484, 50.0% of 2021 Lexus IS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
100.0% of 2021 Lexus IS listings on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 158,694
- Stock #:
- O3411311
- VIN:
- JTHD81F21N5049032

2022 Lexus IS
300 AWD
158,694 mi
$22,605
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- Automatic
- Mileage:
- 35,380
- Stock #:
- 112829
- VIN:
- JTHCA1D27M5112829

2021 Lexus IS
300 RWD
35,380 mi
$31,147
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red 31
- Transmission:
- Automatic
- Mileage:
- 55,587
- Stock #:
- P3013
- VIN:
- JTHCA1D2XM5109455

2021 Lexus IS
300 RWD
55,587 mi
$30,700
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 105,060
- Stock #:
- B120819
- VIN:
- JTHDA1D23N5120819

2022 Lexus IS
300 RWD
105,060 mi
$27,467
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 91,394
- Stock #:
- 5111319
- VIN:
- JTHAA1D22M5111319

2021 Lexus IS
300 RWD
91,394 mi
$27,363
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 134,469
- Stock #:
- SN26226A
- VIN:
- JTHGZ1E23M5021436

2021 Lexus IS
350 F Sport AWD
134,469 mi
$29,432
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- [8Y6] Grecian Water
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 53,782
- VIN:
- JTHDA1D27N5120595
![[8Y6] Grecian Water 2022 Lexus IS Sedan Rear-Wheel Drive Automatic](https://static.cargurus.com/images/forsale/2026/08/31/17/21/2022_lexus_is-pic-7318360420494934933-1024x768.jpeg?io=true&width=640&height=480&fit=bounds&format=jpg&auto=webp)
2022 Lexus IS
300 RWD
53,782 mi
$32,726
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 112,299
- Stock #:
- 042738 LM
- VIN:
- JTHG81F23L5042738

2020 Lexus IS
300 AWD
112,299 mi
$21,990
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 68,379
- Stock #:
- M5018473
- VIN:
- JTHGZ1E25M5018473

2021 Lexus IS
350 F Sport AWD
68,379 mi
$38,190
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 94,279
- Stock #:
- 11-9383
- VIN:
- JTHGZ1E28N5026066

Sponsored Listing
2022 Lexus IS
350 F SPORT AWD
94,279 mi
$31,596
CarGurus Analysis: 2021 Lexus IS
overall

Summary
With 60 currently listed for sale and an average price of $33,484, 50.0% of 2021 Lexus IS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
100.0% of 2021 Lexus IS listings on CarGurus are accident free.
Why it stands out
The 2021 Lexus IS stands out as a compact luxury sports sedan that leans hard into style and driving enjoyment. Lexus describes it as entering a new generation and drawing lessons from the LC and RC, with the goal of appealing to enthusiast drivers and luxury buyers who might otherwise look to German rivals first. That positioning gives the car a more focused personality than a typical comfort-first sedan, and it helps explain why its design and handling are such central parts of its appeal.
What makes the 2021 IS especially distinctive is the combination of stylish design, multiple powertrain options, and strong handling. Those strengths make it attractive to buyers who want a sedan that feels more engaging than merely practical. At the same time, it is not without drawbacks: the base engine is described as underwhelming, the transmission as irritating, and the technology as outdated. Owner feedback broadly reinforces the car’s sporty feel, luxurious atmosphere, and safety features, while also echoing complaints about missing modern tech conveniences and fuel efficiency concerns with the smaller engine.
Other model years to consider
- 2022 Lexus IS
- Average price: $34,420
- Good/great deal percentage: 46.6%
- User rating: 5 / 5
- Total listings: 88
- 2015 Lexus IS
- Average price: $19,797
- Good/great deal percentage: 26.9%
- User rating: 4.6 / 5
- Total listings: 93
- 2023 Lexus IS
- Average price: $43,181
- Good/great deal percentage: 46.2%
- User rating: 4.8 / 5
- Total listings: 93
Similar models to consider
- 2021 BMW 3 Series
- Average price: $27,380
- Good/great deal percentage: 49.4%
- User rating: 5 / 5
- Total listings: 239
- 2021 Audi A4
- Average price: $21,667
- Good/great deal percentage: 37.7%
- User rating: 4.75 / 5
- Total listings: 53
- 2021 Mercedes-Benz C-Class
- Average price: $28,100
- Good/great deal percentage: 52.3%
- User rating: 5 / 5
- Total listings: 216
This analysis is based on CarGurus' proprietary market data from October 5, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis: Worcester, MA Market Report
Pricing in Nearby Cities
Market Area: Worcester, MA
Key Insights
- Highest-Price Market: Manchester, NH leads with an average price of $38,900, indicating a premium market for the Lexus IS.
- Best Value: Hartford, CT offers the lowest average price at $28,445, presenting a more affordable option for buyers.
- Inventory Drives Stability: Hartford, CT also has the most listings at 66, suggesting a robust supply that may stabilize prices.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Hartford, CT | 66 | $28,445 |
| Groton, MA | 65 | $35,947 |
| Providence, RI | 65 | $35,164 |
| Boston, MA | 65 | $35,947 |
| Chicopee, MA | 64 | $28,445 |
| Manchester, NH | 63 | $38,900 |
| Plymouth, MA | 63 | $33,296 |
| New Bedford, MA | 63 | $33,296 |
| Brattleboro, VT | 53 | $28,445 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 300 AWD trim has the highest inventory with 56 listings, indicating strong demand for this configuration.
- Premium Spread: The 350 F Sport AWD trim, priced at $44,950, represents the highest MSRP, reflecting its premium features and performance.
- Drivetrain Effect: The 300 RWD trim, with an MSRP of $39,050, shows a significant price difference compared to the 350 F Sport RWD at $42,950, highlighting the impact of drivetrain choices on pricing.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 44 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 33 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 56 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 21 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2026 model year shows an average price of $50,871, reflecting a 11.8% premium over its starting MSRP of $45,500.
- Depreciation Curve: The 2017 model year has the steepest depreciation at -48.3%, indicating significant value loss over time.
- Best Value Sweet Spot: The 2022 model year is priced at $34,420, which is 12.0% below its starting MSRP, making it an attractive option for budget-conscious buyers.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2026 | $45,500 | $50,871 | +11.8% |
| 2025 | $40,535 | $47,238 | +16.5% |
| 2024 | $40,085 | $44,664 | +11.4% |
| 2023 | $40,085 | $43,081 | +7.5% |
| 2022 | $39,125 | $34,420 | -12.0% |
| 2021 | $39,050 | $33,484 | -14.3% |
| 2020 | $38,560 | $20,995 | -45.6% |
| 2019 | $38,560 | $26,391 | -31.6% |
| 2018 | $38,210 | $22,459 | -41.2% |
| 2017 | $37,825 | $19,539 | -48.3% |
| 2016 | $37,325 | $19,941 | -46.6% |
These recommendations are based on CarGurus' proprietary market data from October 7, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus IS cost?
| Metric | Value |
|---|---|
| Current Average Price | $34,656 |
| Year-Round Low | $33,096 |
| Year-Round High | $35,501 |
| Average Price a Year Ago | $33,982 |
| Change vs. Last Year | +1.98% |
Prices are up 1.98% year-over-year — a sign of continued demand for this model year.
There are 533 listings available, which gives you a modest amount of inventory to compare before you buy.
Is the 2021 Lexus IS a good car?
Yes — 4.62/5 from owners, and the expert rating is 7.33/10. The model scores 8/10 across Look and feel and Cost effectiveness.
Owners consistently praise the stylish design, sporty feel, luxurious atmosphere, handling, and value for money. The same feedback also points to a car that feels well suited to you if you want a compact luxury sedan with personality rather than a purely comfort-first commuter.
The trade-offs are familiar: the base engine is described as underwhelming, the transmission as irritating, and the technology as outdated. That makes the 2021 IS a stronger fit if you care more about driving enjoyment and premium feel than the latest convenience features.
Only 36.2% of listings are priced as good or great deals, so the market still rewards shoppers who move carefully.
Is the 2021 Lexus IS reliable?
Owners rate it 4.62/5, a strong signal of long-term satisfaction.
Owner feedback highlights reliability, quality, and a car you can count on over time, while also reinforcing the brand’s reputation for dependable ownership. The expert notes also point to Lexus’ quality-and-reliability reputation and a well-equipped package that should age well if maintained properly.
The main long-term ownership risk for used buyers is that technology and powertrain satisfaction may not match the car’s strong durability reputation.
What should I look for when buying a used 2021 Lexus IS?
At 71.7% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a close inspection of body panels, paint consistency, and signs of prior repair. It also makes sense to focus on how the car feels on the road, since the transmission and base-engine behavior are recurring concerns in the feedback.
Key things to evaluate:
- Trim level: The lineup includes the IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, and IS 350 AWD F Sport. The F Sport models add a more performance-oriented presentation, while the base trims are the ones most likely to leave you wanting more equipment and presence.
- Powertrain: The IS 300 RWD uses a 2.0-liter turbocharged four-cylinder with 241 horsepower and 258 pound-feet of torque. The IS 300 AWD uses a naturally aspirated 3.5-liter V6 with 260 hp and 236 lb-ft, while the IS 350 models use the same V6 tuned to 311 hp and 280 lb-ft. RWD models use an eight-speed automatic, and AWD models use a six-speed automatic.
- Safety package: Lexus Safety System+ 2.5 is standard and includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. It also includes blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
- Infotainment: The 2021 IS finally offers a touchscreen infotainment system with Android Auto and Apple CarPlay. The touchpad remains, and Lexus Enform Remote, Service Connect, WiFi, and Safety Connect are part of the connected-services mix.
- Fuel efficiency: The IS 300 RWD is rated at 21 mpg city, 31 mpg highway, and 25 mpg combined. The IS 300 AWD is rated at 19/26/22, the IS 350 RWD at 20/28/23, and the IS 350 AWD at 19/26/22.
Which 2021 Lexus IS trim should I buy?
The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.
Here's the short version:
- IS 300 RWD: This is the least expensive entry point and the best-value choice if you want the lowest starting price and the most efficient rear-wheel-drive setup. It gives you the core IS experience without pushing the budget too far.
- IS 300 AWD: Choose this if you want the V6-powered all-wheel-drive setup and are willing to pay more for it. It suits you if traction matters more than outright value.
- IS 350 RWD F Sport: This is the stronger pick if you want the most engaging rear-wheel-drive balance and the more athletic F Sport presentation. It is the trim to target if driving enjoyment matters most.
- IS 350 AWD F Sport: Pick this if you want the top-end AWD version with the strongest output in the lineup and the F Sport treatment. It is the most expensive route and makes sense if you want the fullest feature-and-performance combination.
Lexus Safety System+ 2.5 is standard across the lineup.
Is now a good time to buy a used 2021 Lexus IS?
This is a moderate market for selective buyers, so you should compare listings carefully and move quickly when you find a strong one.
- Deal availability: 36.2% of listings are priced as good or great deals.
- Inventory: There are 533 listings available.
- Price trend: Prices are up 1.98% year-over-year.
- Clean inventory: 71.7% of listings are accident-free.
If you find a listing below $33,096, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus IS's resale value?
The current average of $34,656 sits slightly above last year's $33,982.
That upward move suggests the market has held up reasonably well for this model year, which is a positive sign if you plan to sell later. A price increase like this usually means buyers still see value in the car’s styling, brand appeal, and driving character.
Because the year-round range stays fairly tight, a well-kept example should remain easier to position competitively than a neglected one. Strong demand tends to favor cars that present cleanly, have solid history records, and show consistent maintenance.
Vehicles with strong owner satisfaction ratings, like this model year's 4.62/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus IS safe?
The 2021 Lexus IS hasn’t yet been rated for crashworthiness by the Insurance Institute for Highway Safety (IIHS), nor has it received an overall rating from the National Highway Traffic Safety Administration (NHTSA).
It earns a 7/10 safety score from our experts.
Lexus Safety System+ 2.5 is standard, and it includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. You also get blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
The main caveat is that formal crash-test results were not yet available in the source material, so you should lean more heavily on the standard driver-assistance equipment and the car’s condition when shopping used.
Should I buy a 2021 Lexus IS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 36.2% of listings are priced as good or great deals.
- At 71.7% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices are up 1.98% year-over-year.
- Owners rate it 4.62/5 — a strong satisfaction signal.
- The 2021 brings a new-generation redesign with a touchscreen infotainment system and standard Lexus Safety System+ 2.5.
Consider the 2022 if:
- At $37,551, the 2022 costs more than the current year's $34,656 average.
- It adds a significant performance boost and the new IS 500 F Sport Performance.
The bottom line: If you want the better value and the more accessible entry into this generation, the 2021 is the smarter buy. If you care most about stronger performance and can stretch your budget, the 2022 is the more compelling upgrade. For price-sensitive buyers, the 2021 remains the more balanced path.
These recommendations are based on CarGurus' proprietary market data from October 6, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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