CarGurus Logo Homepage Link
  • Buy
    • Used cars
    • New cars
    • Certified pre-owned
    • Start your purchase online
    • Dealerships near me
  • Sell
    • Sell my car
    • Sell my car FAQs
  • Finance
    • Prequalify for financing
    • How does it work?
    • Financing FAQs
  • Research
    • Test drive reviews
    • Price trends
    • Tips & advice
    • Electric cars
    • Compare cars
  • Discover
    The latest way to shop:
    smarter research, better
    listings.
  • Saved cars & searches
  • Sign in / Register
    • My account
    • Saved searches
    • Saved cars
    • Recommended cars
    • Browsing history
    • Financing dashboard
      • United States (EN)
      • Estados Unidos (ES)
      • Canada (EN)
      • Canada (FR)
      • United Kingdom

Used 2021 Lexus IS for Sale near Irvine, CA

80 results
Irvine, CA
2022 Lexus IS 300 RWD South Coast Mitsubishi

2022 Lexus IS

300 RWD

33,113 miles

$31,995

Fair Deal
Costa Mesa, CA
8 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Silver
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
N/A
Transmission:
Automatic
Mileage:
33,113
Stock number:
K122498
VIN:
JTHDA1D28N5122498

Sponsored

2022 Lexus IS 350 F Sport RWD

2022 Lexus IS

350 F Sport RWD

25,747 miles

$40,000

Good Deal
Certified Pre-Owned
North Hollywood, CA
47 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Cloudburst Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
25,747
Stock number:
B50243
VIN:
JTHGZ1B28N5053630

Sponsored

2022 Lexus IS 350 F Sport RWD

2022 Lexus IS

350 F Sport RWD

50,637 miles

$37,800

Good Deal
Certified Pre-Owned
Torrance, CA
32 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
50,637
Stock number:
U30803T
VIN:
JTHGZ1B23N5049002

Sponsored

2022 Lexus IS 350 F Sport RWD

2022 Lexus IS

350 F Sport RWD

49,052 miles

$37,500

Good Deal
Hemet, CA
44 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
49,052
Stock number:
T29545
VIN:
JTHGZ1B22N5049444

2022 Lexus IS 350 F Sport RWD

2022 Lexus IS

350 F Sport RWD

25,747 miles

$40,000

Good Deal
Certified Pre-Owned
North Hollywood, CA
47 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Cloudburst Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
25,747
Stock number:
B50243
VIN:
JTHGZ1B28N5053630

2021 Lexus IS 300 RWD

2021 Lexus IS

300 RWD

47,386 miles

$30,999

Fair Deal
Montclair, CA
27 mi away
Year:
2021
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel w/Black Metallic Trim
Transmission:
Automatic
Mileage:
47,386
Stock number:
M5116164
VIN:
JTHCA1D21M5116164

Preparing for a close up...

Photos coming soon

2022 Lexus IS

300 RWD

50,649 miles

$29,499

Good Deal
Santa Ana, CA
6 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Black w/Open-Pore Black Wood Trim
Transmission:
Automatic
Mileage:
50,649
Stock number:
N5120422
VIN:
JTHDA1D29N5120422

Preparing for a close up...

Photos coming soon

2020 Lexus IS

300 RWD

97,127 miles

$19,885

Great Deal
North Hollywood, CA
49 mi away
Year:
2020
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
97,127
Stock number:
L5107903Y
VIN:
JTHDA1D28L5107903

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

27,792 miles

$41,724

Fair Deal
Certified Pre-Owned
Riverside, CA
27 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Iridium
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
Automatic
Mileage:
27,792
Stock number:
00CP7940
VIN:
JTHGZ1B21N5054621

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

19,772 miles

$40,841

Fair Deal
Santa Monica, CA
46 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
19,772
Stock number:
L052021
VIN:
JTHGZ1B20N5052021

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

45,130 miles

$38,881

Fair Deal
Fontana, CA
37 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black w/Black
Transmission:
8-Speed Automatic
Mileage:
45,130
Stock number:
N5049487P
VIN:
JTHGZ1B29N5049487

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

40,304 miles

$40,837

Fair Deal
Certified Pre-Owned
Riverside, CA
27 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
40,304
Stock number:
00CP7965
VIN:
JTHGZ1B25N5050149

Preparing for a close up...

Photos coming soon

2022 Lexus IS

300 RWD

60,801 miles

$29,837

Fair Deal
Certified Pre-Owned
Riverside, CA
27 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel
Transmission:
Automatic
Mileage:
60,801
Stock number:
00CP7942
VIN:
JTHAA1D29N5119676

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

8,139 miles

$41,985

Fair Deal
San Juan Capistrano, CA
16 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red w/Ash Trim
Transmission:
Automatic
Mileage:
8,139
Stock number:
AV16406
VIN:
JTHGZ1B24N5055777

Preparing for a close up...

Photos coming soon

2020 Lexus IS

300 RWD

94,000 miles

$23,090

Great Deal
La Habra, CA
20 mi away
Year:
2020
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Atomic Silver
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
94,000
Stock number:
2695N34
VIN:
JTHAA1D21L5106871

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

42,464 miles

$38,859

Fair Deal
Cerritos, CA
21 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black w/Black
Transmission:
Automatic
Mileage:
42,464
Stock number:
N5052725
VIN:
JTHGZ1B23N5052725

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

46,627 miles

$38,997

Good Deal
Store transfer to Irvine, CA
2,091 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Red
Transmission:
Automatic
Mileage:
46,627
Stock number:
27688558
VIN:
JTHGZ1B25N5049034

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

36,904 miles

$40,998

Fair Deal
Ontario, CA
28 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Red
Transmission:
Automatic
Mileage:
36,904
Stock number:
28234641
VIN:
JTHGZ1B21N5053968

Preparing for a close up...

Photos coming soon

2021 Lexus IS

350 F Sport RWD

22,881 miles

$39,800

Good Deal
Certified Pre-Owned
Chino, CA
21 mi away
Year:
2021
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black W/Black
Transmission:
8-Speed Automatic
Mileage:
22,881
Stock number:
TF9344
VIN:
JTHGZ1B29M5047205

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

50,637 miles

$37,800

Good Deal
Certified Pre-Owned
Torrance, CA
32 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
50,637
Stock number:
U30803T
VIN:
JTHGZ1B23N5049002

Preparing for a close up...

Photos coming soon

2021 Lexus IS

300 RWD

47,386 miles

$30,999

Fair Deal
Montclair, CA
27 mi away
Year:
2021
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel w/Black Metallic Trim
Transmission:
Automatic
Mileage:
47,386
Stock number:
M5116164
VIN:
JTHCA1D21M5116164

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus IS
  4. / 2021
  5. / California
  6. / Irvine
Overview
Reviews
FAQs
Picture of 2021 Lexus IS

Lexus amps up its compact sports sedan for a new generation.

The Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be.

4.6 Overall rating

(16 reviews)
Robert O
5.0
Reviewed a 2021 Lexus IS on Jan 15, 2024

Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!

Amy N
5.0
Reviewed a 2021 Lexus IS on Aug 14, 2021

Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.

Anonymous
5.0
Reviewed a 2021 Lexus IS on Feb 11, 2023

This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.

Jason M
5.0
Reviewed a 2021 Lexus IS on Apr 21, 2023

Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.

Hugo B
5.0
Reviewed a 2021 Lexus IS on Oct 29, 2022

Amazing looking car! The infrared color was a good choice. Handling and drive is good. Just a little upset that there is not wireless apple car play, so you have to use the cord. Other than that, I’m Really enjoying drive !

2021 Lexus IS FAQs

How much does the 2021 Lexus IS cost in Irvine, CA?

The average 2021 Lexus IS costs about $34,198.33. The average price has decreased by -4.4% since last year. The 80 for sale near Irvine, CA on CarGurus, range from $18,997 to $70,488 in price.

Is the 2021 Lexus IS a good car?

CarGurus experts gave the 2021 Lexus IS an overall rating of 7.3/10 and 2021 Lexus IS owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus IS vehicles in Irvine, CA have no reported accidents or damage?

67 out of 80 for sale near Irvine, CA have no reported accidents or damage.

Is the 2021 Lexus IS safe?

CarGurus experts gave the 2021 Lexus IS a safety rating of 7/10.

What is the fuel economy of the 2021 Lexus IS?

Depending on the engine and options, the 2021 Lexus IS gets between 20 and 25 MPG (or MPGe).

What fuel types are available?

Gasoline engines are available.

  • 2024 Lexus IS

  • 2023 Lexus IS

  • 2022 Lexus IS in Irvine CA

  • 2020 Lexus IS

  • 2019 Lexus IS

  • 2018 Lexus IS

  • Lexus IS 300 RWD

  • Lexus IS 350 F Sport RWD

  • Lexus IS 300 AWD

  • Lexus IS 350 F Sport AWD in Irvine CA

  • 2021 Lexus IS in Los Angeles CA

  • 2021 Lexus IS in Temecula CA

  • 2021 Lexus IS in Escondido CA

  • Lexus IS in Irvine CA

  • Lexus SUVs & Crossovers for Sale in Irvine CA

  • Sports Cars for Sale in Irvine CA

  • Sports Cars Under $20,000 for Sale in Irvine CA

  • Reliable Cars For Sale in Irvine CA

  • Lexus Coupes for Sale Near Irvine CA

  • Affordable Luxury Cars For Sale in Irvine CA

  • Used Luxury Cars for Sale in Irvine CA

  • All Used Cars

  • Manual Transmission Cars

  • Luxury Cars

  • Cars with Red Interior

  • Cheap Manual Cars

  • Hybrid Cars

  • Sports Cars

  • Electric SUVs

  • Cheap Trucks

  • Small Cars

  • Third Row SUVs

  • Three Quarter Ton Trucks

  • Lifted Trucks

  • Manual Transmission Trucks

  • Diesel Trucks

  • Hybrid SUVs

  • Dually Trucks

  • One Ton Trucks

  • Cheap SUVs

  • Lifted Ford Trucks

  • 4x4 Trucks

  • Work Trucks

  • AWD SUVs

  • Ford Trucks

  • Chevrolet Trucks

  • Toyota Trucks

  • Trucks Under $10,000

  • Cars Under $15,000

  • Sports Cars Under $20,000

  • Trucks Under $20,000

  • Used Sedans for Sale with Low Mileage

  • Used SUVs / Crossovers for Sale with Low Mileage

  • Used Hatchbacks for Sale with Low Mileage

  • Used Convertibles for Sale with Low Mileage

  • Used Vans for Sale with Low Mileage

  • Used Minivans for Sale with Low Mileage

  • Used Pickup Trucks for Sale with Low Mileage

  • Used Coupes for Sale with Low Mileage

  • Used Wagons for Sale with Low Mileage

  • Lexus of Cerritos

  • Newport Lexus

  • Temecula Valley Lexus

  • Lexus of Westminster

  • Lexus of Glendale

  • South County Lexus

  • Lexus Carlsbad

  • Longo Lexus

  • Tustin Lexus

Connect with us
Download our app
Download on the App Store Get it on Google Play
  • Company
  • About CarGurus
  • Our team
  • Press
  • Investor relations
  • Price trends
  • Careers
  • Advertise with CarGurus
  • For dealers
  • Dealer signup
  • Dealer resources
  • Terms
  • Terms of use
  • Privacy policy
  • Interest-based ads
  • Security
  • Help
  • Help center
  • Contact us
Click for the BBB Business Review of this Auto Listing Service in Cambridge MA
    • United States (EN)
    • Estados Unidos (ES)
    • Canada (EN)
    • Canada (FR)
    • United Kingdom

© 2025 CarGurus, Inc., All Rights Reserved.