Used 2021 Lexus IS for Sale near Escondido, CA
51 results
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 30,781
- Stock #:
- P04137LC
- VIN:
- JTHSZ1B29N5050861
Sponsored by Temecula Valley Lexus
2022 Lexus IS
350 F Sport RWD
30,781 mi
$43,244
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 28,930
- Stock #:
- N5056133
- VIN:
- JTHGZ1B29N5056133
Sponsored Listing
2022 Lexus IS
350 F Sport RWD
28,930 mi
$42,985
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Ash
- Transmission:
- Automatic
- Mileage:
- 33,479
- Stock #:
- 10698
- VIN:
- JTHSZ1B23N5053092
Sponsored Listing
2022 Lexus IS
350 F Sport RWD
33,479 mi
$45,084
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 30,781
- Stock #:
- P04137LC
- VIN:
- JTHSZ1B29N5050861
2022 Lexus IS
350 F Sport RWD
30,781 mi
$43,244
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,841
- Stock #:
- 61982
- VIN:
- JTHGZ1B25N5053178
2022 Lexus IS
350 F Sport RWD
58,841 mi
$37,204
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 41,386
- Stock #:
- 62178
- VIN:
- JTHGZ1B2XM5037900
2021 Lexus IS
350 F Sport RWD
41,386 mi
$38,204
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 49,471
- Stock #:
- M5040807
- VIN:
- JTHGZ1B22M5040807
2021 Lexus IS
350 F Sport RWD
49,471 mi
$36,804
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 58,051
- Stock #:
- 70041385
- VIN:
- JTHAA1D21L5108801
2020 Lexus IS
300 RWD
58,051 mi
$25,998
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 46,637
- Stock #:
- N5049370
- VIN:
- JTHGZ1B2XN5049370
2022 Lexus IS
350 F Sport RWD
46,637 mi
$38,712
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 67,696
- Stock #:
- ZC1719
- VIN:
- JTHGZ1E21M5021967
2021 Lexus IS
350 F Sport AWD
67,696 mi
$36,591
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 41,181
- Stock #:
- 29252
- VIN:
- JTHGZ1B26N5056932
2022 Lexus IS
350 F Sport RWD
41,181 mi
$40,432
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel w/Black Metallic Trim
- Transmission:
- Automatic
- Mileage:
- 38,035
- Stock #:
- M5046798
- VIN:
- JTHC81F28M5046798
2021 Lexus IS
300 AWD
38,035 mi
$34,892
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- Automatic
- Mileage:
- 78,340
- Stock #:
- M5117726
- VIN:
- JTHCA1D20M5117726
2021 Lexus IS
300 RWD
78,340 mi
$29,904
CarGurus Analysis:
2021 Lexus IS
With 485 currently listed for sale and an average price of $35,491.00, 33.4% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars.
72.4% of 2021 IS models on CarGurus are accident free.
The 2021 Lexus IS stands out with its sporty design, multiple powertrain options, and impressive handling, making it a favorite among luxury buyers.
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 28,930
- Stock #:
- N5056133
- VIN:
- JTHGZ1B29N5056133
2022 Lexus IS
350 F Sport RWD
28,930 mi
$42,985
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 72,640
- Stock #:
- 774
- VIN:
- JTHAA1D27L5104235
2020 Lexus IS
300 RWD
72,640 mi
$26,394
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 64,886
- Stock #:
- N5056859
- VIN:
- JTHGZ1B20N5056859
2022 Lexus IS
350 F Sport RWD
64,886 mi
$38,592
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Ash
- Transmission:
- Automatic
- Mileage:
- 33,479
- Stock #:
- 10698
- VIN:
- JTHSZ1B23N5053092
2022 Lexus IS
350 F Sport RWD
33,479 mi
$45,084
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black Metallic Trim
- Transmission:
- Automatic
- Mileage:
- 53,908
- Stock #:
- M5112892
- VIN:
- JTHCA1D23M5112892
2021 Lexus IS
300 RWD
53,908 mi
$32,888
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- CREAM
- Transmission:
- Automatic
- Mileage:
- 46,440
- Stock #:
- 28764905
- VIN:
- JTHGZ1B28M5046529
2021 Lexus IS
350 F Sport RWD
46,440 mi
$40,597
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 59,457
- Stock #:
- 27928530
- VIN:
- JTHGZ1B26L5036189
2020 Lexus IS
350 RWD
59,457 mi
$32,998
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- Automatic
- Mileage:
- 111,887
- Stock #:
- 106410
- VIN:
- JTHAA1D29L5106410
2020 Lexus IS
300 RWD
111,887 mi
$23,524
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- Automatic
- Mileage:
- 38,659
- Stock #:
- 107953
- VIN:
- JTHAA1D28L5107953
2020 Lexus IS
300 RWD
38,659 mi
$29,619
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 78,223
- Stock #:
- 019136
- VIN:
- JTHGZ1E23M5019136
2021 Lexus IS
350 F Sport AWD
78,223 mi
$36,468
CarGurus Analysis: 2021 Lexus IS
overall
Summary
With 485 currently listed for sale and an average price of $35,491.00, 33.4% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars.
72.4% of 2021 IS models on CarGurus are accident free.
The 2021 Lexus IS stands out with its sporty design, multiple powertrain options, and impressive handling, making it a favorite among luxury buyers.
Why it stands out
The 2021 Lexus IS embodies a refined balance of luxury and performance, designed to cater to both enthusiast drivers and those seeking a prestigious ride. Its sleek, athletic silhouette not only captures attention but also signals the car's sporty aspirations. Under the hood, the IS offers diverse engine choices; from the 241-horsepower base engine to a robust 311-horsepower option, ensuring a satisfying driving experience tailored to different preferences. Furthermore, the integration of cutting-edge safety features through the Lexus Safety System+ 2.5 enhances appeal, placing safety on par with performance. While some users have expressed dissatisfaction regarding outdated technology and fuel efficiency, the overall feedback remains positive, underscoring the car's luxurious feel, driving dynamics, and value for money.
Other model years to consider
- Average price: $38,352.00
- Good/great deal percentage: 33.9%
- User rating: 5 / 5
- Total listings: 983
- Average price: $42,156.00
- Good/great deal percentage: 34.7%
- User rating: 4.8 / 5
- Total listings: 1,219
- Average price: $44,144.00
- Good/great deal percentage: 36.3%
- Total listings: 1,337
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
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4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
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