Used 2021 Lexus IS for Sale nearSan Diego, CA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- Automatic
- Mileage:
- 67,849
- Stock #:
- 10824
- VIN:
- JTHGA1D25L5103160

Sponsored Listing
2020 Lexus IS
300 RWD
67,849 mi
$28,582
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel w/Black Metallic Trim
- Transmission:
- Automatic
- Mileage:
- 39,306
- Stock #:
- 12419TIS-LA
- VIN:
- JTHDA1D2XN5118730

2022 Lexus IS
300 RWD
39,306 mi
$34,119
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 47,000
- Stock #:
- WEB547841
- VIN:
- JTHGZ1E26L5017976

2020 Lexus IS
350 AWD
47,000 mi
$36,975
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 71,178
- Stock #:
- 70199552
- VIN:
- JTHGZ1B27M5048532

2021 Lexus IS
350 F Sport RWD
71,178 mi
$35,998
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White Pearl
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 93,062
- Stock #:
- L5107472
- VIN:
- JTHDA1D27L5107472

-$501
2020 Lexus IS
300 RWD
93,062 mi
$24,285
$23,784
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- Automatic
- Mileage:
- 67,849
- Stock #:
- 10824
- VIN:
- JTHGA1D25L5103160

2020 Lexus IS
300 RWD
67,849 mi
$28,582
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 113,736
- Stock #:
- 056676
- VIN:
- JTHGZ1B23N5056676

2022 Lexus IS
350 F Sport RWD
113,736 mi
$31,798
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 41,181
- Stock #:
- 29252
- VIN:
- JTHGZ1B26N5056932

2022 Lexus IS
350 F Sport RWD
41,181 mi
$39,083
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 50,492
- Stock #:
- 70036354
- VIN:
- JTHAA1D20L5102584

2020 Lexus IS
300 RWD
50,492 mi
$27,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gold
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 122,272
- Stock #:
- 040470
- VIN:
- JTHGZ1B24M5040470

2021 Lexus IS
350 F Sport RWD
122,272 mi
$30,598
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 72,640
- Stock #:
- 774
- VIN:
- JTHAA1D27L5104235

2020 Lexus IS
300 RWD
72,640 mi
$26,497
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- NEBULA GRAY PEARL
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 89,047
- Stock #:
- 6104237
- VIN:
- JTHAA1D2XL5102138

2020 Lexus IS
300 RWD
89,047 mi
$26,891
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,695
- Stock #:
- 44431
- VIN:
- JTHGZ1B27N5049374

2022 Lexus IS
350 F Sport RWD
65,695 mi
$37,184
CarGurus Analysis:
2021 Lexus IS
With 58 currently listed for sale near San Diego, CA and an average price of $39,955.00, 17.2% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
94.8% of 2021 Lexus IS models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 57,862
- Stock #:
- H5486
- VIN:
- JTHGZ1B22N5051288

2022 Lexus IS
350 F Sport RWD
57,862 mi
$38,720
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 55,697
- Stock #:
- 29681
- VIN:
- JTHAA1D2XL5105556

2020 Lexus IS
300 RWD
55,697 mi
$27,441
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 44,345
- Stock #:
- 038020
- VIN:
- JTHGZ1B27M5038020

2021 Lexus IS
350 F Sport RWD
44,345 mi
$39,510
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 132,540
- Stock #:
- 2026-389
- VIN:
- JTHGZ1B20N5049068

2022 Lexus IS
350 F Sport RWD
132,540 mi
$29,894
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red w/Dark Gray Streamline Trim
- Transmission:
- Automatic
- Mileage:
- 68,606
- Stock #:
- 101898
- VIN:
- JTHGA1D24L5101898

2020 Lexus IS
300 RWD
68,606 mi
$28,381
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 48,677
- Stock #:
- 28725537
- VIN:
- JTHGZ1B26M5046609

2021 Lexus IS
350 F Sport RWD
48,677 mi
$39,397
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 48,080
- Stock #:
- R037399
- VIN:
- JTHGZ1B29M5037399

2021 Lexus IS
350 F Sport RWD
48,080 mi
$39,367
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 59,056
- Stock #:
- N5054202
- VIN:
- JTHGZ1B23N5054202

2022 Lexus IS
350 F Sport RWD
59,056 mi
$40,474
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 68,843
- Stock #:
- M5037337
- VIN:
- JTHGZ1B29M5037337

2021 Lexus IS
350 F Sport RWD
68,843 mi
$36,129
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,094
- Stock #:
- 050864
- VIN:
- JTHGZ1B27N5050864

2022 Lexus IS
350 F Sport RWD
96,094 mi
$34,767
CarGurus Analysis: 2021 Lexus IS
overall

Summary
With 58 currently listed for sale near San Diego, CA and an average price of $39,955.00, 17.2% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
94.8% of 2021 Lexus IS models on CarGurus are accident free.
Why it stands out
The 2021 Lexus IS stands out as a compact luxury sports sedan that leans hard into style and driving enjoyment. Lexus describes it as entering its fourth generation and drawing lessons from the LC and RC, while also aiming at enthusiast drivers and luxury buyers who might otherwise think German first. That positioning gives the car a clear identity: it is meant to feel more expressive and more driver-focused than a typical small luxury sedan.
Its strongest appeal comes from the combination of stylish design, multiple powertrain options, and great handling. Those traits make it attractive to buyers who want a premium sedan with a sporty edge rather than a purely comfort-oriented commute car. At the same time, the 2021 Lexus IS is not without compromises, and the reported drawbacks include an underwhelming base engine, an irritating transmission, and outdated technology. Owner feedback generally reinforces the car’s style, sporty feel, and luxurious character, while also pointing to missing modern tech features and concerns about fuel efficiency with the smaller engine option.
Other model years to consider
- Average price: $45,781.00
- Good/great deal percentage: 47.4%
- User rating: 4.8 / 5
- Total listings: 95
- Average price: $19,427.00
- Good/great deal percentage: 21.6%
- User rating: 4.6 / 5
- Total listings: 74
- Average price: $42,341.00
- Good/great deal percentage: 55.4%
- Total listings: 92
This analysis is based on CarGurus' proprietary market data from August 25, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis: San Diego, CA Market Report
Pricing by Nearby Locations
Market Area: San Diego, CA
Key Insights
- Highest Prices in Escondido: The city of Escondido has the highest average price at $36,925, likely reflecting a demand for luxury vehicles in the area.
- Lowest Prices in Palm Desert: Palm Desert offers the lowest average price at $32,500, indicating a more price-sensitive market or higher inventory turnover.
- Inventory Variation: Cities like Irvine (91 listings) and Pomona (93 listings) have substantial inventory, which may contribute to more stable pricing around the regional average.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Escondido, CA | 60 | $36,925 |
| Temecula, CA | 66 | $35,917 |
| Irvine, CA | 91 | $35,901 |
| Palm Desert, CA | 58 | $32,500 |
| San Bernardino, CA | 86 | $35,676 |
| Pomona, CA | 93 | $35,364 |
| Los Angeles, CA | 86 | $35,551 |
| Victorville, CA | 68 | $35,828 |
| Malibu, CA | 68 | $34,698 |
| Santa Clarita, CA | 65 | $35,160 |
Pricing by Trim Packages
Key Insights
- RWD Trims Lead Inventory: The 300 RWD trim is the most common with 48 listings, indicating strong demand for rear-wheel drive configurations.
- Price Range Across Trims: The 350 F Sport AWD trim, priced at $44,950 MSRP, is the highest, reflecting a premium for sport features and AWD capability.
- Feature-Rich Base Trim: The 300 RWD trim offers a competitive price at $39,050 MSRP, with a robust set of features appealing to a broad audience.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 48 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 45 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 26 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 6 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models at a Premium: The 2025 Lexus IS is priced at $47,411, which is 16.5% above MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2017 Lexus IS shows a steep decline, priced at $17,153, reflecting a depreciation of 54.7% from its original MSRP.
- Best Value in Recent Models: The 2020 Lexus IS offers a balance of price and features, with an average price of $24,796, down 35.5% from MSRP, making it an attractive option for buyers.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2025 | $40,535 | $47,411 | +16.5% |
| 2024 | $40,085 | $44,311 | +10.5% |
| 2023 | $40,085 | $48,932 | +21.9% |
| 2020 | $38,560 | $24,796 | -35.5% |
| 2019 | $38,560 | $21,085 | -45.3% |
| 2018 | $38,210 | $28,915 | -24.0% |
| 2017 | $37,825 | $17,153 | -54.7% |
| 2016 | $37,325 | $20,109 | -46.1% |
| 2015 | $36,550 | $20,207 | -44.8% |
| 2014 | $36,100 | $16,233 | -55.0% |
These recommendations are based on CarGurus' proprietary market data from August 27, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus IS cost?
| Metric | Value |
|---|---|
| Current Average Price | $35,119 |
| Year-Round Low | $33,155.14 |
| Year-Round High | $35,699.11 |
| Average Price a Year Ago | $34,408 |
| Change vs. Last Year | +2.07% |
Prices are up 2.07% year-over-year — a sign of continued demand for this model year.
There are 521 listings available, which gives you a modest amount of inventory to compare before you buy.
If you find a listing below $33,155.14, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Lexus IS a good car?
Yes — the 2021 Lexus IS earns a 4.62/5 user rating, and our experts rate it 7.33/10. The model scores 8/10 across Look and feel and Cost effectiveness.
Owners consistently praise the stylish design, sporty feel, and luxurious character. They also highlight the handling and value for money, while the overview points to a clear appeal for buyers who want a premium sedan with a sporty edge rather than a comfort-first commuter.
The main trade-offs are the underwhelming base engine, the irritating transmission, and outdated technology. That means you should expect the strongest appeal if you care more about driving feel and design than about the latest cabin tech.
With 27.4% of listings marked as good or great deals, there is still some room to shop selectively.
Is the 2021 Lexus IS reliable?
Owners rate it 4.62/5, a strong signal of long-term satisfaction.
The owner summary points to a car that feels dependable, with buyers repeatedly calling out the stylish design, sporty feel, and luxurious character they can count on. The expert notes also emphasize Lexus’ reputation for quality and reliability, which supports the case for long-term ownership.
The performance write-up adds that the IS feels crisp, precise, and balanced, which reinforces the sense of a well-sorted car rather than one that feels loosely assembled or hard to live with.
If you buy used, the main long-term risk is less about outright durability and more about whether the specific car has been maintained well and equipped to your expectations.
What should I look for when buying a used 2021 Lexus IS?
At 72.4% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if the car has been in any collision. Focus on body condition, panel alignment, tire wear, and signs that the car’s sporty suspension and steering have been used hard or repaired poorly.
Key things to evaluate:
- Trim level: The cabin is described as tastefully simple, but the tech and luxury presentation can feel more basic than some rivals, and the base setup lacks some modern conveniences buyers may expect.
- Powertrain: The IS 300 RWD uses a 2.0-liter turbocharged four-cylinder with 241 horsepower and 258 pound-feet of torque, while the IS 300 AWD uses a 3.5-liter V6 with 260 hp and 236 lb-ft; IS 350 models use the V6 tuned to 311 hp and 280 lb-ft. Fuel economy ranges from 21 mpg city, 31 mpg highway, 25 mpg combined for the IS 300 RWD to 19/26/22 for the IS 300 AWD, and 20/28/23 for the IS 350 RWD to 19/26/22 for the IS 350 AWD.
- Safety package: Lexus Safety System+ 2.5 is standard and includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. It also includes blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
- Infotainment: The 2021 IS finally gets a touchscreen infotainment system with Android Auto and Apple CarPlay. Lexus Enform Service Connect comes with a 10-year complimentary subscription, Lexus Enform Remote is free for three years, and the Navigation Package includes Dynamic Navigation and Destination Assist for the first three years only.
- Fuel efficiency: The EPA estimates 21 mpg city, 31 mpg highway, 25 mpg combined for the IS 300 RWD; 19/26/22 for the IS 300 AWD; 20/28/23 for the IS 350 RWD; and 19/26/22 for the IS 350 AWD.
Which 2021 Lexus IS trim should I buy?
The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.
Here's the short version:
- IS 300 RWD: This is the least expensive way into the lineup, and it gives you the 2.0-liter turbo four-cylinder, rear-wheel drive, and the best fuel economy in the group. It makes the most sense if you want the lowest entry price and still care about the car’s sporty character.
- IS 300 AWD: Choose this if you want the V6 and all-wheel drive without stepping up to the higher-output F Sport models. It adds traction and a smoother-feeling powertrain, but it costs more and returns lower fuel economy.
- IS 350 RWD F Sport: This is the best-value choice if you want the strongest blend of performance and price. You get the more powerful 311-hp V6, rear-wheel drive, and the sharper F Sport setup without paying for AWD.
- IS 350 AWD F Sport: Pick this if you want the top gas-model performance with all-weather traction. It is the priciest version, so it makes the most sense if you specifically want the extra capability and are willing to pay for it.
Lexus Safety System+ 2.5 is standard across the lineup, so you do not need to move up trims for the core safety suite.
Is now a good time to buy a used 2021 Lexus IS?
Act selectively, because this is still a seller’s market and the best cars will move quickly.
- Deal availability: 27.4% of listings are priced as good or great deals.
- Inventory: There are 521 listings available.
- Price trend: Prices are up 2.07% year-over-year.
- Clean inventory: 72.4% of listings are accident-free.
If you find a listing below $33,155.14, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus IS's resale value?
The current average of $35,119 sits slightly above last year's $34,408.
That upward move suggests the market has held up reasonably well for this model year. If you buy carefully and keep the car in good condition, you should have a decent chance of preserving value better than you would with a weaker-demand luxury sedan.
The price range also shows that buyers are still willing to pay for the right example, especially one with the right trim, condition, and history. That matters because a car with steady demand is usually easier to sell later without taking a steep haircut.
Vehicles with strong owner satisfaction ratings, like this model year's 4.62/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus IS safe?
It hasn’t yet been rated for crashworthiness by IIHS or NHTSA.
It earns a 7/10 safety score from our experts.
Lexus Safety System+ 2.5 is standard, and it includes a pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. You also get blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect with SOS emergency assistance, roadside assistance, automatic collision notification, and stolen vehicle notification.
The main caveat is that formal crash-test results were not yet available in the source data, so you should lean more heavily on the standard safety equipment and the condition of any used example you consider.
Should I buy a 2021 Lexus IS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 27.4% of listings are priced as good or great deals.
- At 72.4% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices are up 2.07% year-over-year.
- Owners rate it 4.62/5 — a strong satisfaction signal.
- The 2021 brings a fourth-generation redesign with sharper styling, multiple powertrain choices, and a touchscreen infotainment system.
Consider the 2022 if:
- At $37,875, the 2022 costs more than the current year's $35,119 average.
- It adds the IS 500 F Sport Performance with a 5.0-liter V8 and much stronger performance.
The bottom line: If you want the best balance of price, style, and sporty character, the 2021 is the smarter buy. If your priority is maximum performance and you can spend more, the 2022 is the better path. For most used-car shoppers, the 2021 offers the stronger value proposition, while price-sensitive buyers should focus on well-kept examples near the low end of the market.
These recommendations are based on CarGurus' proprietary market data from August 28, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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