CarGurus Header

2022 Mercedes-Benz GLS vs 2022 Lexus RX

2022 Lexus RX
2022 Lexus RX
$45,920MSRP
Overview
Overview
OverviewShop Now
2022 Mercedes-Benz GLS
2022 Mercedes-Benz GLS
$77,850MSRP
Overview
Overview
OverviewShop Now
2022 Lexus RX
$45,920MSRP
Overview
Overview
OverviewShop Now
2022 Mercedes-Benz GLS
$77,850MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP

$45,920

MSRP

$77,850

Listings

8

Listings

8

Ratings & Reviews

User Reviews
User Reviews

Expert reviews

7.3 out of 10

Expert reviews

7.3 out of 10

Pros

  • Great ride quality

  • Standard advanced safety features

Cons

  • Potentially polarizing design

  • Poor ergonomic design

Pros

  • Stylish design

  • Powerful engine

  • Spacious

Cons

  • Poor ride quality

  • Advanced safety features are not standard

  • Poor ergonomic design

2022 Lexus RX Reviews Summary

Likely on the tail end of this fourth generation, the Lexus RX was last redesigned in 2015 with a mild mid-cycle refresh for the 2020 model year. But to consider the RX long in the tooth would be a mistake. Not only is it the automaker’s best-selling model, but the RX also enjoyed its best-ever sales year in 2021. A carryover for 2022, the Lexus RX sees minimal changes which include new colors and a standalone fog lamps option.

2022 Mercedes-Benz GLS Reviews Summary

The 2022 Mercedes-Benz GLS-Class sits at the top of the automaker’s luxury SUV range. The three-row GLS is the biggest SUV Mercedes offers, and the “S” in its names signifies its status as the SUV equivalent of Mercedes’ flagship S-Class sedan.

The SUV that’s now known as the GLS was launched for the 2007 model year as the GL-Class, when Mercedes decided it needed a bigger, more luxurious SUV to sit above the M-Class in its lineup. The GL-Class and M-Class were rebadged GLS-Class and GLE-Class, respectively, in 2014 when Mercedes introduced a new naming scheme across its lineup.

The current version of the GLS was introduced for the 2020 model year, and represents the model’s third generation. It’s aimed at other full-size luxury SUVs, including the BMW X7, Cadillac Escalade, Infiniti QX80, Land Rover Range Rover, Lincoln Navigator, and Lexus LX.

Mercedes withdrew most of its V8 models from the United States for the 2022 model year, leaving only the base six-cylinder GLS 450 4Matic model. The automaker is expected to begin resuming dealer orders for V8 models as you read this, though, so the GLS 580 4Matic, AMG GLS 63, and Maybach GLS 600 4Matic models should return to showrooms soon. Because it was the only version available at the time, we tested a GLS 450 for this review.

No video found

Popular Features & Specs

Engine

3.5L 295 hp V6

Engine

3.0L 362 hp I6

Drive Train

FWD

Drive Train

AWD

Seating Capacity

5

Seating Capacity

7

Horsepower

295 hp @ 6300 rpm

Horsepower

362 hp @ 5500 rpm

MPG City

20

MPG City

18

MPG Highway

27

MPG Highway

24
2022 Lexus RX
2022 Lexus RX
$45,920MSRP
Overview
Overview
OverviewShop Now
2022 Mercedes-Benz GLS
2022 Mercedes-Benz GLS
$77,850MSRP
Overview
Overview
OverviewShop Now
2022 Lexus RX
$45,920MSRP
Overview
Overview
OverviewShop Now
2022 Mercedes-Benz GLS
$77,850MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP
$45,920
$77,850
Listings

Ratings & Reviews

User reviews

4.6

5.0

Expert reviews

7.3 out of 10

Read full review

7.3 out of 10

Read full review
Pros & cons

Pros

  • Great ride quality

  • Standard advanced safety features

Cons

  • Potentially polarizing design

  • Poor ergonomic design

Pros

  • Stylish design

  • Powerful engine

  • Spacious

Cons

  • Poor ride quality

  • Advanced safety features are not standard

  • Poor ergonomic design

Summary
Likely on the tail end of this fourth generation, the Lexus RX was last redesigned in 2015 with a mild mid-cycle refresh for the 2020 model year. But to consider the RX long in the tooth would be a mistake. Not only is it the automaker’s best-selling model, but the RX also enjoyed its best-ever sales year in 2021. A carryover for 2022, the Lexus RX sees minimal changes which include new colors and a standalone fog lamps option.

The 2022 Mercedes-Benz GLS-Class sits at the top of the automaker’s luxury SUV range. The three-row GLS is the biggest SUV Mercedes offers, and the “S” in its names signifies its status as the SUV equivalent of Mercedes’ flagship S-Class sedan.

The SUV that’s now known as the GLS was launched for the 2007 model year as the GL-Class, when Mercedes decided it needed a bigger, more luxurious SUV to sit above the M-Class in its lineup. The GL-Class and M-Class were rebadged GLS-Class and GLE-Class, respectively, in 2014 when Mercedes introduced a new naming scheme across its lineup.

The current version of the GLS was introduced for the 2020 model year, and represents the model’s third generation. It’s aimed at other full-size luxury SUVs, including the BMW X7, Cadillac Escalade, Infiniti QX80, Land Rover Range Rover, Lincoln Navigator, and Lexus LX.

Mercedes withdrew most of its V8 models from the United States for the 2022 model year, leaving only the base six-cylinder GLS 450 4Matic model. The automaker is expected to begin resuming dealer orders for V8 models as you read this, though, so the GLS 580 4Matic, AMG GLS 63, and Maybach GLS 600 4Matic models should return to showrooms soon. Because it was the only version available at the time, we tested a GLS 450 for this review.

Video
No video found

Popular Features & Specs

Engine
3.5L 295 hp V6
3.0L 362 hp I6
Drive Train
FWD
AWD
Seating Capacity
5
7
Horsepower
295 hp @ 6300 rpm
362 hp @ 5500 rpm
MPG City
20
18
MPG Highway
27
24
Look and feel

2022 Lexus RX

7/10

2022 Mercedes-Benz GLS

9/10

The 2022 Lexus RX presented a modern and sporty design, available in base 350, F Sport, and L trim levels, with a hybrid RX 450h model. The RX 350 and F Sport offered seating for five, while the L trim provided a three-row, 7-passenger option. The RX's design, with its sharp character lines and angular features, was aggressive yet restrained, making it stand out among competitors like the Audi Q5 and BMW X5. The F Sport trim, in particular, added a performance-oriented appearance with 20-inch wheels and unique front fascia, enhancing its sporty appeal. Inside, the RX maintained a luxury feel, with F Sport models adding sporty elements like Scored Aluminum trim and NuLuxe synthetic leather. However, the center stack felt dated, and the seats, especially in the F Sport, lacked comfort and adjustability.

The 2022 Mercedes-Benz GLS, in its base GLS 450 form, offered a more subtle and less flashy look compared to rivals like the Cadillac Escalade and BMW X7. The AMG GLS 63 and Maybach versions added visual drama with features like flared wheel arches and chrome accents. Inside, the GLS provided a luxurious feel with leather upholstery, a panoramic roof, and ambient lighting. The digital instrument cluster and infotainment touchscreen were well-integrated, enhancing the interior's modern appeal. However, the GLS 450's suspension lacked refinement, leading to excessive motion over bumps. Despite this, the GLS 450's inline-six engine, assisted by the EQ Boost mild-hybrid system, delivered smooth and sufficient power, making it a strong contender in the luxury SUV segment.

Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Picture of 2022 Lexus RX
Performance

2022 Lexus RX

7/10

2022 Mercedes-Benz GLS

7/10

The 2022 Lexus RX 350 was powered by a 3.5-liter V6 engine producing 295 horsepower and 267 pound-feet of torque, while the hybrid RX 450h combined the V6 with electric motors for a total of 308 hp. All RX models featured an eight-speed automatic transmission, with FWD standard on the RX 350 and AWD available. Despite the F Sport designation, the RX lacked true sporty performance, with an engine note more akin to a turbocharged four-cylinder and unimpressive acceleration. The F Sport Handling package added features like adaptive variable suspension and a Sport+ drive mode, but changes in driving dynamics were minimal. The RX excelled in comfort and cabin quietness, offering a serene ride. Fuel efficiency for the RX 350 was 20 mpg city and 27 mpg highway, while the RX 450h hybrid achieved 30 mpg combined.

The 2022 Mercedes-Benz GLS 450 featured a 3.0-liter turbocharged inline-six engine with 362 horsepower and 369 pound-feet of torque, assisted by the EQ Boost mild-hybrid system. The electric motor added 21 hp and 184 lb-ft of torque in short bursts, enhancing performance. The GLS 450's engine provided ample power, and the inline-six's smoothness suited the luxury SUV. However, the air suspension lacked refinement, leading to excessive body motion. The GLS 450 had a towing capacity of 7,700 pounds, slightly less than some competitors. Overall, the GLS 450 offered a balanced performance with a focus on luxury and comfort.

Form and function

2022 Lexus RX

7/10

2022 Mercedes-Benz GLS

8/10

The 2022 Lexus RX offered 99.8 cubic feet of passenger volume in its two-row configuration, comfortably seating four adults. The three-row L models shared the same wheelbase, resulting in limited space for the third row. Cargo space in the standard RX was 16.0 cubic feet behind the second row, expanding to 32.6 cubic feet with the seats folded. The three-row version offered 7.45 cubic feet with all seats up, increasing to 58.48 cubic feet with both back rows down. The RX featured thoughtful interior elements like a smartphone slot and adjustable-height cup holder, but the rear seats didn't fold completely flat, and the cargo area's load-in height was high.

The 2022 Mercedes-Benz GLS came standard with a seven-seat configuration, with an optional six-seat version featuring captain's chairs. The second-row seats could slide and fold for third-row access, offering excellent legroom. Cargo space was 17.4 cubic feet with all seats in place, expanding to 84.7 cubic feet with the second and third rows folded. The GLS provided easy loading with power-folding seats and a power tailgate, and the air suspension could lower for easier access. However, the touchscreen was difficult to reach, and some ergonomic issues were noted, such as the center console's grab handles.

Technology

2022 Lexus RX

7/10

2022 Mercedes-Benz GLS

7/10

The 2022 Lexus RX featured an 8-inch touchscreen as standard, with a 12.3-inch version available. Despite being moved closer to the driver, the screen's positioning was ergonomically unfriendly, with a lip obstructing access. The infotainment system was responsive, but the touchpad controller was frustrating to use. The RX offered a range of tech features, including six USB ports, Android Auto and Apple CarPlay, wireless charging, and a WiFi hotspot. The Lexus App provided remote engine start and vehicle settings.

The 2022 Mercedes-Benz GLS came with the MBUX infotainment system, featuring a 12.3-inch touchscreen and digital instrument cluster. The system included Bluetooth, Apple CarPlay/Android Auto, navigation, and a Burmester audio system. Users had multiple control options, with voice recognition being the most effective. The touchpad controller was overly sensitive, and the navigation system occasionally suggested inefficient routes. Despite these issues, the GLS offered a comprehensive tech package with high-quality graphics.

Safety

2022 Lexus RX

8/10

2022 Mercedes-Benz GLS

6/10

The 2022 Lexus RX came standard with the Lexus Safety System 2.0+, which included adaptive cruise control, lane-departure warning, road-sign recognition, and a pre-collision system. Additional features included blind-spot monitoring, rear cross-traffic alert, and a head-up display. The RX was named a Top Safety Pick by the IIHS with optional headlights but received four stars overall from the NHTSA.

The 2022 Mercedes-Benz GLS included forward collision warning, automatic emergency braking, blind-spot monitoring, and a surround-view camera system. Optional features included adaptive cruise control and lane-keep assist. The GLS had not been rated by the IIHS or NHTSA at the time of publication.

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for the 2022 Lexus RX is 7.3 out of 10, while the 2022 Mercedes-Benz GLS scores 7.3 out of 10. Both vehicles offer unique strengths, but the GLS stands out with its luxurious interior, advanced technology, and spaciousness, making it the recommended choice for those seeking a premium SUV experience.

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for the 2022 Lexus RX is 7.3 out of 10, while the 2022 Mercedes-Benz GLS scores 7.3 out of 10. Both vehicles offer unique strengths, but the GLS stands out with its luxurious interior, advanced technology, and spaciousness, making it the recommended choice for those seeking a premium SUV experience.

CarGurus logo

By: CarGurus + AI

At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.

Popular vehicle comparisons

2023 Audi Q3 vs 2023 Mercedes-Benz GLS2023 Mercedes-Benz GLS vs 2023 Volvo XC402023 MINI Countryman vs 2024 Mercedes-Benz GLS2023 Jeep Wrangler 4xe vs 2024 Mercedes-Benz GLS2023 Nissan Rogue vs 2024 Mercedes-Benz GLS2023 Mercedes-Benz GLS vs 2023 Mitsubishi Outlander Sport2023 MINI Countryman vs 2023 Mercedes-Benz GLS2023 Honda Odyssey vs 2023 Mercedes-Benz GLS2023 Chrysler Pacifica Hybrid vs 2024 Mercedes-Benz GLS2023 Lexus RX vs 2023 Lexus GX2023 MINI Countryman vs 2023 Lexus RX2023 Toyota Sienna vs 2024 Mercedes-Benz GLS2023 Mercedes-Benz GLS vs 2023 Lincoln Navigator2023 Volkswagen Tiguan vs 2024 Mercedes-Benz GLS2023 Mercedes-Benz GLS vs 2023 Volvo XC902022 Volvo XC40 vs 2023 Mercedes-Benz GLS2022 Volvo XC40 vs 2023 Lexus RX2022 Toyota Sienna vs 2023 Mercedes-Benz GLS2022 Chrysler Pacifica Hybrid vs 2023 Mercedes-Benz GLS2022 Buick Enclave vs 2023 Lexus RX2022 Lexus RX Hybrid vs 2023 Lexus RX2022 Lexus NX vs 2023 Lexus RX2022 Nissan Rogue vs 2023 Mercedes-Benz GLS2022 Chrysler Pacifica vs 2023 Lexus RX2022 Toyota Sienna vs 2023 Lexus RX2022 Mitsubishi Outlander Sport vs 2023 Mercedes-Benz GLS2022 MINI Countryman vs 2023 Lexus RX2022 Jeep Grand Cherokee L vs 2023 Mercedes-Benz GLS2022 Volvo XC90 vs 2023 Mercedes-Benz GLS2022 Lincoln Navigator vs 2023 Lexus RX2021 Mercedes-Benz GLS vs 2022 Jeep Wrangler 4xe2021 Lexus RX vs 2022 Volvo XC402021 Lexus RX vs 2022 Honda Odyssey2021 Lexus RX vs 2022 Lexus GX2021 Lexus RX vs 2022 Lincoln Aviator2021 Mercedes-Benz GLS vs 2022 Mitsubishi Outlander Sport2021 Mercedes-Benz GLS vs 2022 Buick Encore2021 Lexus RX vs 2022 Jeep Wrangler 4xe2021 Mercedes-Benz GLS vs 2022 Toyota Sienna2021 Lexus RX vs 2022 Lincoln Navigator2021 Mercedes-Benz GLS vs 2022 Volkswagen Tiguan2021 Mercedes-Benz GLS vs 2022 Honda Passport2021 Lexus RX vs 2022 Chrysler Pacifica2021 Mercedes-Benz GLS vs 2022 Jeep Grand Cherokee L2020 Lexus RX vs 2020 Lexus RX Hybrid2020 Toyota Sienna vs 2020 Lexus RX2020 Volvo XC90 vs 2020 Lexus RX2020 Mitsubishi Outlander Sport vs 2020 Lexus RX2020 Mercedes-Benz GLS vs 2020 Audi Q32020 Lexus GX vs 2021 Lexus RX2020 Lexus RX vs 2020 Honda CR-V2020 Nissan Rogue vs 2020 Lexus RX2020 Chrysler Pacifica Hybrid vs 2021 Lexus RX2020 Mercedes-Benz GLS vs 2020 Chrysler Pacifica Hybrid2020 Lincoln Aviator vs 2020 Lexus RX2020 Mercedes-Benz GLS vs 2020 Lincoln Navigator2020 Buick Enclave vs 2020 Mercedes-Benz GLS2020 Buick Enclave vs 2021 Lexus RX2019 Honda Passport vs 2020 Mercedes-Benz GLS2019 Chrysler Pacifica Hybrid vs 2020 Mercedes-Benz GLS2019 Chrysler Pacifica vs 2020 Lexus RX2019 Honda CR-V vs 2020 Mercedes-Benz GLS2019 MINI Countryman vs 2020 Mercedes-Benz GLS2019 Volvo XC90 vs 2020 Lexus RX2019 Volvo XC90 vs 2020 Mercedes-Benz GLS2019 Toyota Sienna vs 2020 Lexus RX2019 Lexus GX vs 2020 Lexus RX2019 Chrysler Pacifica Hybrid vs 2020 Lexus RX2019 Buick Enclave vs 2020 Lexus RX2019 MINI Countryman vs 2020 Lexus RX2019 Lexus NX vs 2020 Lexus RX2019 Honda Odyssey vs 2020 Mercedes-Benz GLS
CarGurus Footer