2021 Nissan Murano vs 2022 Toyota Sienna
Overview | |
MSRP$32,810 | MSRP$35,285 |
Listings553 | Listings585 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews7.8 out of 10 | Expert reviews8.7 out of 10 |
Pros
Cons
| Pros
Cons
|
2021 Nissan Murano Reviews SummaryWhile most midsize SUVs offer three rows, the 2021 Nissan Murano focuses on two rows of comfortable seating. Rivals like the Honda Passport have come on the scene in recent years, but Nissan’s comfortable crossover never left. The Murano was introduced in 2002 as a 2003 model, and the third generation arrived for the 2015 model year. Last refreshed for 2019, the Murano carries over into the 2021 model year largely unchanged, although it does get some additional standard safety features. | |
2022 Toyota Sienna Reviews SummaryThe 2022 Toyota Sienna hybrid minivan rolls into the second model year following a redesign for 2021. Last year’s successful makeover with a standard hybrid powertrain returns unchanged, but a new Woodland trim level is available to attract adventurous families (or those who want to look that way). | |
No video found | No video found |
Popular Features & Specs | |
Engine3.5L 260 hp V6 | Engine2.5L 245 hp I4 Hybrid |
Drive TrainFWD | Drive TrainFWD |
Seating Capacity5 | Seating Capacity8 |
Horsepower260 hp @ 6000 rpm | Horsepower |
EV Battery Capacity | EV Battery Capacity1.9 kWh |
MPG City20 | MPG City36 |
MPG Highway28 | MPG Highway36 |
Engine | |
Engine Name3.5L 260 hp V6 | Engine Name2.5L 245 hp I4 Hybrid |
Torque240 lb-ft @ 4400 rpm | Torque |
Horsepower260 hp @ 6000 rpm | Horsepower |
DrivetrainFWD | DrivetrainFWD |
Fuel Economy | |
EV Battery Capacity | EV Battery Capacity1.9 kWh |
MPG City20 | MPG City36 |
MPG Highway28 | MPG Highway36 |
Interior | |
Seating Capacity5 | Seating Capacity8 |
Safety | |
Front Crash Overall5 | Front Crash Overall4 |
Side Crash Overall5 | Side Crash Overall5 |
Dimensions & Capacity | |
Cargo Space32.1 cu ft | Cargo Space33.5 cu ft |
Curb Weight3833 lbs | Curb Weight4610 lbs |
Height67.8 in | Height68.5 in |
Length192.8 in | Length203.7 in |
Width75.4 in | Width78.5 in |
Wheelbase111.2 in | Wheelbase120.5 in |
Maximum Payload1277 lbs | Maximum Payload1560 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity | Maximum Towing Capacity3500 lbs |
Overview | ||
MSRP | $32,810 | $35,285 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 7.8 out of 10Read full review | 8.7 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | While most midsize SUVs offer three rows, the 2021 Nissan Murano focuses on two rows of comfortable seating. Rivals like the Honda Passport have come on the scene in recent years, but Nissan’s comfortable crossover never left. The Murano was introduced in 2002 as a 2003 model, and the third generation arrived for the 2015 model year. Last refreshed for 2019, the Murano carries over into the 2021 model year largely unchanged, although it does get some additional standard safety features. | The 2022 Toyota Sienna hybrid minivan rolls into the second model year following a redesign for 2021. Last year’s successful makeover with a standard hybrid powertrain returns unchanged, but a new Woodland trim level is available to attract adventurous families (or those who want to look that way). |
Video | No video found | No video found |
Popular Features & Specs | ||
Engine | 3.5L 260 hp V6 | 2.5L 245 hp I4 Hybrid |
Drive Train | FWD | FWD |
Seating Capacity | 5 | 8 |
Horsepower | 260 hp @ 6000 rpm | |
EV Battery Capacity | 1.9 kWh | |
MPG City | 20 | 36 |
MPG Highway | 28 | 36 |
Engine | ||
Engine Name | 3.5L 260 hp V6 | 2.5L 245 hp I4 Hybrid |
Torque | 240 lb-ft @ 4400 rpm | |
Horsepower | 260 hp @ 6000 rpm | |
Drivetrain | FWD | FWD |
Fuel Economy | ||
EV Battery Capacity | 1.9 kWh | |
MPG City | 20 | 36 |
MPG Highway | 28 | 36 |
Interior | ||
Seating Capacity | 5 | 8 |
Safety | ||
Front Crash Overall | 5 | 4 |
Side Crash Overall | 5 | 5 |
Dimensions & Capacity | ||
Cargo Space | 32.1 cu ft | 33.5 cu ft |
Curb Weight | 3833 lbs | 4610 lbs |
Height | 67.8 in | 68.5 in |
Length | 192.8 in | 203.7 in |
Width | 75.4 in | 78.5 in |
Wheelbase | 111.2 in | 120.5 in |
Maximum Payload | 1277 lbs | 1560 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 3500 lbs | |
The 2021 Nissan Murano had a design that was once ahead of its time, but by 2021, its L-shaped LED headlights and contoured front end had become standard in car design. Its interior was more conservative, focusing on comfort and ease of use, making it an ideal SUV for commutes and road trips. The cabin's restrained styling ensured that all controls were intuitively placed, minimizing any learning curve for new drivers.
The Murano was available in four trims: S, SV, SL, and Platinum. The base S trim came with 18-inch alloy wheels, manual front seats, dual-zone climate control, four USB ports, push-button start, remote keyless entry, satellite radio, Bluetooth connectivity, and an 8-inch touchscreen with Apple CarPlay and Android Auto. Higher trims added features like power-adjustable front seats, adaptive cruise control, leather upholstery, heated seats, a Bose premium stereo system, and a dual-panel panoramic moonroof.
Toyota's Sienna minivan had a long history, dating back to its debut in 1998. By 2022, the Sienna had evolved to present an SUV-like style while retaining its minivan functionality. The latest model featured a macho front end, re-engineered door hinges, and a sleek profile with integrated styling details. The base models came with 17-inch wheels, while upper trims offered 18-inch and 20-inch wheels.
Inside, the Sienna avoided the typical minivan feel with an uncluttered design and ample storage. It offered comfortable seating for second- and third-row passengers, with available second-row captain’s chairs and a spacious third-row bench. The third row was a 60/40-split bench that easily stored away into the floor, and the second-row seats slid up to 25 inches for easy access to the third row.














The 2021 Nissan Murano was powered by a 3.5-liter V6 engine, producing 260 horsepower and 240 pound-feet of torque. This engine was paired with a continuously variable transmission (CVT) and came with standard front-wheel drive (FWD) or optional all-wheel drive (AWD). The V6 provided strong low-speed acceleration, making it great for city driving, though the CVT dulled its power at higher speeds. The Murano had a comfort-first ride, with refined driving characteristics that allowed it to handle corners well and absorb road bumps. However, its towing capacity was limited to 1,500 pounds, which was lower than many other midsize SUVs.
The 2022 Toyota Sienna carried over its hybrid powertrain from the previous year, combining a 2.5-liter four-cylinder engine with two electric motors to produce 243 horsepower. FWD was standard, with AWD available on all trims. The AWD system used a separate electric motor for the rear wheels, simplifying the mechanical setup. The Sienna used an electronically controlled CVT, offering four selectable drive modes: Normal, EV, Eco, and Sport. The Sienna's handling was impressive for a minivan, thanks to its TNGA platform, which provided minimal body roll and a comfortable ride. The big news was its fuel economy, with FWD models achieving 36 mpg city/highway/combined and AWD models getting 35 mpg city/highway/combined. The Sienna's 288-volt nickel metal-hydride battery pack was tucked under the front seats and came with a 10-year/150,000-mile warranty.
The 2021 Nissan Murano offered up to 67 cubic feet of cargo space with the rear seats folded and 32.1 cubic feet with the rear seats in use. While this was less than some competitors, the Murano made up for it with ease of use, featuring a traditional shifter design and a center console loaded with trays and cubbies. The Murano excelled in providing ample headroom and legroom for both front and second-row passengers, with the second-row seats offering partial reclining functionality.
The 2022 Toyota Sienna was designed to be a family workhorse, capable of carrying a full 4x8 sheet of plywood with the tailgate closed. It offered 33.5 cubic feet of cargo space behind the third row, 75.2 cubic feet behind the second row, and 101 cubic feet behind the first row. The Sienna also had a 3,500-pound towing capacity. The third-row bench easily stored away into the floor, and each row had ample storage cubbies and cupholders. Both side sliding doors and the rear tailgate were power-operated with foot-motion triggers, making it convenient for loading and unloading.
The 2021 Nissan Murano came standard with an 8-inch touchscreen infotainment system, featuring a sensible menu layout and hard buttons and dials for easy navigation. It included Apple CarPlay and Android Auto, with available upgrades like an 11-speaker Bose premium stereo system and navigation.
The 2022 Toyota Sienna was packed with technology features, including a standard 9-inch touchscreen with Apple CarPlay, Android Auto, Amazon Alexa, SiriusXM, one USB media port, and six USB charging ports. However, it lacked wireless Apple CarPlay and Android Auto. The Sienna offered a one-year trial of Safety Connect and Remote Connect, a 10-year trial of Service Connect, and a three-month trial of AT&T WiFi Connect. Higher trims featured a 12-speaker JBL audio system, a rear-seat entertainment system with an 11.6-inch display, and a 10-inch color head-up display. Limited and Platinum models could upgrade to a digital rearview mirror and included Qi wireless phone charging.
The 2021 Nissan Murano came with standard driver assistance features as part of Nissan Safety Shield 360, including reverse automatic emergency braking, blind-spot monitoring, rear cross-traffic alert, lane departure warning, and automatic high beams. Additional features like a surround-view parking monitor, adaptive cruise control, traffic sign recognition, and front-and-rear parking sensors were available.
The 2022 Toyota Sienna received a Top Safety Pick+ rating from the IIHS and a five-star rating from the NHTSA. It came with the Toyota Safety Sense 2.0 suite, which included adaptive cruise control, Lane Tracing Assist, forward collision warning, automatic emergency braking, lane departure warning, automatic high beams, and traffic sign recognition. The Sienna also featured 10 airbags, multiple LATCH connectors, a rear-seat reminder system, tire-pressure monitoring, and an inflator kit. A spare tire was available, mounted in the cargo space wall for convenience.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Nissan Murano is 7.8 out of 10, while the 2022 Toyota Sienna scores 8.7 out of 10. Based on these ratings, the 2022 Toyota Sienna is the clear winner, offering superior technology, safety features, and fuel efficiency, making it the better choice for families and those seeking a versatile and reliable vehicle.
Choose the 2021 Nissan Murano if:
- You prioritize a comfort-first ride with refined driving characteristics.
- You prefer a traditional shifter design and intuitive control layout.
- You want a two-row SUV with ample headroom and legroom for all passengers.
Choose the 2022 Toyota Sienna if:
- You need a versatile family vehicle with ample cargo space and seating flexibility.
- You value advanced technology features and a comprehensive suite of driver aids.
- You want a fuel-efficient hybrid powertrain with impressive fuel economy ratings.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Nissan Murano is 7.8 out of 10, while the 2022 Toyota Sienna scores 8.7 out of 10. Based on these ratings, the 2022 Toyota Sienna is the clear winner, offering superior technology, safety features, and fuel efficiency, making it the better choice for families and those seeking a versatile and reliable vehicle.
Choose the 2021 Nissan Murano if:
Shop Now- You prioritize a comfort-first ride with refined driving characteristics.
- You prefer a traditional shifter design and intuitive control layout.
- You want a two-row SUV with ample headroom and legroom for all passengers.
Choose the 2022 Toyota Sienna if:
Shop Now- You need a versatile family vehicle with ample cargo space and seating flexibility.
- You value advanced technology features and a comprehensive suite of driver aids.
- You want a fuel-efficient hybrid powertrain with impressive fuel economy ratings.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.




































