Used Mercedes-Benz S-Class for Sale near Kansas City, MO
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2022 Mercedes-Benz S-Class
Shop 2022 Mercedes-Benz S-Class »With 223 currently listed for sale near Kansas City, MO and an average price of $66,522.00, 45.7% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
91.0% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class is equipped with a modern executive transportation design, featuring a 48-volt mild hybrid gasoline-electric powertrain, providing a seamless blend of performance and efficiency with its turbocharged engine options.
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4.7 Overall rating
Customers say
The Mercedes-Benz S-Class has consistently impressed drivers with its luxurious feel, outstanding performance, and advanced technology across all model years. Owners particularly appreciate the comfortable and spacious interiors, the smooth ride, and the powerful engines. Many have praised features such as safety innovations and craftsmanship that highlight the brand's commitment to luxury. However, some common concerns among owners include high maintenance costs, issues with technology reliability, and a steep price tag compared to other models. Overall, the S-Class remains a top choice for those seeking a high-end driving experience.
AI generated from the text of customer reviews.
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What people say
Moises S
Reviewed a 2020 Mercedes-Benz S-Class on Jun 20, 2024
the features of an S class are the very reasons that this car is of good value. this is the flagship of Mercedes Benz so there is no comparison.
Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Amy K
Reviewed a 2016 Mercedes-Benz S 550 4MATIC on Aug 27, 2025
Beautiful car lots of luxury features great handling and power!
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 500 4MATIC | $119,550 |
| S 580 4MATIC | $130,700 |
| Maybach S 680 4MATIC | $244,400 |
| AMG S 63 E Performance 4MATIC | $189,800 |
| S 580e 4MATIC | $130,400 |
| Maybach S 580 4MATIC | $207,150 |
Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of Mercedes-Benz S-Class prices has changed over time.
See more price trendsCarGurus recommends the 2022 Mercedes-Benz S-Class

Summary
With 223 currently listed for sale near Kansas City, MO and an average price of $66,522.00, 45.7% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
91.0% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class is equipped with a modern executive transportation design, featuring a 48-volt mild hybrid gasoline-electric powertrain, providing a seamless blend of performance and efficiency with its turbocharged engine options.
Why it stands out
The 2022 Mercedes-Benz S-Class continues its reputation as the flagship sedan for luxury and performance. Known for its unmatched comfort and sophisticated technology, it offers an exceptional driving experience. The design is sleek and modern, maintaining an impressive silhouette that stands out in any setting. With advanced features like the 12.8-inch OLED touchscreen, a high-quality Burmester sound system, and state-of-the-art driver assistance technologies, the S-Class caters not just to the driver but to all passengers. Its impressive powertrain options, including mild hybrid technology, enable smooth acceleration and impressive fuel efficiency, making it an appealing choice for those seeking a high-end driving experience without compromise.
Other model years to consider
- Average price: $19,995.00
- Good/great deal percentage: 35.2%
- User rating: 4.9 / 5
- Total listings: 165
- Average price: $17,590.00
- Good/great deal percentage: 34.9%
- User rating: 5 / 5
- Total listings: 152
- Average price: $36,495.00
- Good/great deal percentage: 37.1%
- User rating: 4.79 / 5
- Total listings: 167
These recommendations are based on CarGurus' proprietary market data from May 26, 2026, CarGurus experts' opinions, and generative AI.
Recent expert test drives

2025 Mercedes-Benz S-Class
- Expert review7/10
- MSRP$117,750-$240,500
- Avg. price$147,032
- User rating5
2023 Mercedes-Benz S-Class
- Expert review9/10
- MSRP$114,500-$229,000
- Avg. price$79,938
- User rating0

2021 Mercedes-Benz S-Class
- Expert review8/10
- MSRP$109,800-$185,400
- Avg. price$66,510
- User rating4
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