Used 2022 Toyota Sequoia for Sale near Iowa

Is the 2022 Toyota Sequoia a good car?

Yes — the 2022 Toyota Sequoia earns a 5/5 user rating and a 7.33/10 expert rating. The model scores 8/10 across Performance, Form and function, and Cost effectiveness.

It fits you best if you want a classic body-on-frame, three-row, full-size SUV with truck-based strength, plenty of cargo space, and standard advanced safety features. The trade-offs are clear: the fuel economy is poor, the technology is outdated, and the interior styling feels dated. If you value durability, space, and a traditional SUV layout over modern polish, that balance can still work well for you.

Good and great deals make up 35.2% of listings, which gives you some room to shop selectively.

Is the 2022 Toyota Sequoia reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The 2022 Sequoia leans on a proven truck-based platform, a single 5.7-liter V8, and a six-speed automatic, and the expert review says that combination has an excellent reputation for durability and reliability. It also emphasizes that the SUV is made to last, with tight assembly and high-quality materials inside. Toyota’s own wording points to a vehicle built for longevity rather than flash.

For used buyers, the main long-term ownership risk is that age-related wear and dated technology can matter more than the underlying mechanical reputation.

What should I look for when buying a used 2022 Toyota Sequoia?

Accident-free inventory is solid at 87.1% — always verify the vehicle history report.

You should still check the history report carefully, because a clean listing percentage does not replace a vehicle-by-vehicle inspection. Prioritize the condition of the interior, the operation of the infotainment system, and the overall wear on a truck-based SUV that may have seen family duty or towing use. It also makes sense to confirm that the safety and convenience features you want are present on the trim you’re considering.

Key things to evaluate:

• Trim level: The Sequoia’s trim spread includes SR5, TRD Sport, TRD Pro, Limited, Platinum, and Nightshade Special Edition. The base SR5 is the starting point, while the Limited adds more convenience and the Nightshade Special Edition layers on darkened exterior trim and black-painted wheels. If you want the most rugged character, the TRD Pro stands apart with its off-road focus.
• Powertrain: You get one engine choice: a 5.7-liter V8 with 381 horsepower and 401 pound-feet of torque, paired with a six-speed automatic. Rear-wheel drive is standard, four-wheel drive is available, and TRD Pro models come with standard 4WD. Fuel economy is 13 mpg city/17 mpg highway/15 mpg combined with RWD and 13 mpg city/17 mpg highway/14 mpg combined with 4WD.
• Safety package: Toyota Safety Sense P is standard and includes pre-collision system with pedestrian detection, adaptive cruise control, lane-departure alert, and automatic high beams. Standard blind-spot monitor with rear cross-traffic alert is also included, along with Toyota’s STAR safety system. Base trims still get the full safety suite.
• Infotainment: The standard setup uses a 7-inch touchscreen with Apple CarPlay and Android Auto, plus WiFi connectivity and SiriusXM satellite radio. The Limited adds navigation and a 12-speaker audio system, and a premium package brings native navigation, 14 JBL speakers, a subwoofer, and an amplifier.
• Fuel efficiency: The Sequoia returns 13 mpg city/17 mpg highway/15 mpg combined with rear-wheel drive and 13 mpg city/17 mpg highway/14 mpg combined with four-wheel drive.

Which 2022 Toyota Sequoia trim should I buy?

The 2022 Toyota Sequoia is offered in 6 trim levels: SR5, TRD Sport, TRD Pro, Limited, Platinum, and Nightshade Special Edition.

Here's the short version:

• SR5: This is the entry point, and it gives you the Sequoia’s core strengths without extra frills. It’s the trim to consider if you want the lowest starting price and are mainly focused on space, V8 power, and standard safety equipment.
• TRD Sport: This trim adds a more styled, sportier presentation while staying close to the Sequoia’s basic formula. It makes sense if you want a little more visual presence without moving too far up the price ladder.
• TRD Pro: This is the one to choose if you want the most off-road-oriented version. The content specifically notes special suspension tuning for the TRD Pro, so it’s the best fit if trail capability matters to you.
• Limited: This is the best-value trim for many shoppers because it adds navigation and a 12-speaker audio system while staying below the top-end luxury trims. It also serves as the basis for the Nightshade Special Edition.
• Nightshade Special Edition: This is the style-focused choice, with darkened chrome or black exterior trim and black-painted 20-inch wheels. Pick it if you want the Limited’s foundation with a more distinctive look.
• Platinum: This is the top trim and the right choice if you want the most upscale Sequoia experience. It sits at the top of the range and is the trim to consider if you want maximum equipment.

Toyota Safety Sense P and blind-spot monitoring are standard across the lineup, so you do not need to move up a trim just to get the core safety package.

Is now a good time to buy a used 2022 Toyota Sequoia?

This looks like a moderate, selective-buyer market, so you should shop carefully and compare listings before moving quickly.

• Deal availability: 35.2% of listings are priced as good or great deals.
• Inventory: There are 403 listings available.
• Clean inventory: 87.1% of listings are accident-free.

Is the 2022 Toyota Sequoia safe?

The 2022 Toyota Sequoia does not have crash-test ratings from NHTSA or IIHS.

It earns a 7/10 safety score from our experts.

Toyota Safety Sense P is standard and includes pre-collision system with pedestrian detection, adaptive cruise control, lane-departure alert, and automatic high beams. You also get standard blind-spot monitoring with rear cross-traffic alert, plus Toyota’s STAR safety system with stability control, traction control, anti-lock brakes, electronic brake-force distribution, brake assist, and smart-stop technology. A full complement of airbags, LATCH connectors, trailer sway-control, parking-assist sonar, child-protector rear door locks, and power window lockouts are also included.

The main caveat is that there are no published crash-test results, so you’re relying on the standard safety equipment and the Sequoia’s size rather than formal ratings.

Should I buy a 2022 Toyota Sequoia or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 35.2% of listings are priced as good or great deals.
• Accident-free inventory is solid at 87.1% — always verify the vehicle history report.
• Owners rate it 5/5 — a strong satisfaction signal.
• It keeps the traditional V8, truck-based layout, and standard advanced safety features.

Consider the 2021 if:

• It offers similar space and capability with an older, familiar full-size SUV formula.

Consider the 2023 if:

• It brings a redesigned cabin and a standard hybrid powertrain.

The bottom line: The 2022 is the right pick if you want the last version of the Sequoia’s old-school, V8-powered formula with strong safety equipment and a proven truck-based character. If you’re price-sensitive and mainly want the same basic space and capability, the 2021 can make sense; if you want a more modern Sequoia, the 2023 is the better direction.

These recommendations are based on CarGurus' proprietary market data from September 11, 2026, CarGurus experts' opinions, and generative AI.