Used 2022 Mercedes-Benz GLS for Sale nearPittsburgh, PA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 50,600
- Stock #:
- X11237A
- VIN:
- 4JGFF5KE7NA747610

Sponsored Listing
2022 Mercedes-Benz GLS
450 4MATIC
50,600 mi
$44,478
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,597
- Stock #:
- LP2836A
- VIN:
- 4JGFF5KE0MA489803

Sponsored Listing
2021 Mercedes-Benz GLS
450 4MATIC
36,597 mi
$36,478
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,597
- Stock #:
- LP2836A
- VIN:
- 4JGFF5KE0MA489803

2021 Mercedes-Benz GLS
450 4MATIC
36,597 mi
$36,478
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 93,744
- Stock #:
- AW260157A
- VIN:
- 4JGFF5KEXMA442083

2021 Mercedes-Benz GLS
450 4MATIC
93,744 mi
$28,628
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 87,802
- Stock #:
- HP1291
- VIN:
- 4JGFF5KE5NA648574

2022 Mercedes-Benz GLS
450 4MATIC
87,802 mi
$35,987
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 50,600
- Stock #:
- X11237A
- VIN:
- 4JGFF5KE7NA747610

2022 Mercedes-Benz GLS
450 4MATIC
50,600 mi
$44,478
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Obsidian Black Metallic
- Fuel type:
- Gasoline
- Interior color:
- Black w/Diamond Stitching
- Transmission:
- 9-Speed Automatic
- Mileage:
- 35,662
- Stock #:
- AP260051A
- VIN:
- 4JGFF8KE2NA800991

2022 Mercedes-Benz GLS
AMG GLS 63 4MATIC
35,662 mi
$75,971
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 86,623
- Stock #:
- 10804
- VIN:
- 4JGFF5KE2NA585952

2022 Mercedes-Benz GLS
450 4MATIC
86,623 mi
$38,109
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 54,920
- Stock #:
- X902667
- VIN:
- 4JGFF5KE8PA902667

2023 Mercedes-Benz GLS
450 4MATIC
54,920 mi
$50,637
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 51,240
- Stock #:
- W14880
- VIN:
- 4JGFF5KE4MA424923

2021 Mercedes-Benz GLS
450 4MATIC
51,240 mi
$40,952
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Crystal White/Silver Gray Pearl
- Transmission:
- 9-Speed Automatic
- Mileage:
- 25,885
- Stock #:
- 661585
- VIN:
- 4JGFF5KE9NA661585

2022 Mercedes-Benz GLS
450 4MATIC
25,885 mi
$51,252
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,600
- Stock #:
- 428333
- VIN:
- 4JGFF5KE3MA428333

2021 Mercedes-Benz GLS
450 4MATIC
38,600 mi
$42,734
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato
- Transmission:
- 9-Speed Automatic
- Mileage:
- 68,614
- Stock #:
- E58804
- VIN:
- 4JGFF5KE1MA458804

2021 Mercedes-Benz GLS
450 4MATIC
68,614 mi
$36,202
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 175 currently listed for sale and an average price of $56,234, 28.6% of 2022 Mercedes-Benz GLS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
84.6% of 2022 Mercedes-Benz GLS listings on CarGurus are accident free.
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Tartufo Brown/Black
- Transmission:
- Automatic
- Mileage:
- 29,987
- Stock #:
- 005549
- VIN:
- 4JGFF8KE4PB005549

2023 Mercedes-Benz GLS
AMG GLS 63 4MATIC
29,987 mi
$87,763
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,346
- Stock #:
- 314813
- VIN:
- 4JGFF8KE4MA314813

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
30,346 mi
$77,914
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- Automatic
- Mileage:
- 71,000
- Stock #:
- 22684
- VIN:
- 4JGFF5KE1MA429934

2021 Mercedes-Benz GLS
450 4MATIC
71,000 mi
$35,055
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,225
- Stock #:
- D2126A
- VIN:
- 4JGFF5KE4NA664359

2022 Mercedes-Benz GLS
450 4MATIC
64,225 mi
$44,786
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 44,654
- Stock #:
- E2663A
- VIN:
- 4JGFF5KE7NA630724

-$1,335
2022 Mercedes-Benz GLS
450 4MATIC
44,654 mi
$42,333
$40,998
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 60,434
- Stock #:
- 1MT4940
- VIN:
- 4JGFF5KE7NA804940

2022 Mercedes-Benz GLS
450 4MATIC
60,434 mi
$42,122
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 57,148
- Stock #:
- PA911931
- VIN:
- 4JGFF5KE0PA911931

2023 Mercedes-Benz GLS
450 4MATIC
57,148 mi
$50,096
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 15,328
- Stock #:
- PNA727950
- VIN:
- 4JGFF5KE8NA727950

2022 Mercedes-Benz GLS
450 4MATIC
15,328 mi
$53,614
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 50,971
- Stock #:
- NA700459
- VIN:
- 4JGFF5KE3NA700459

2022 Mercedes-Benz GLS
450 4MATIC
50,971 mi
$45,612
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 76,976
- Stock #:
- 461154
- VIN:
- 4JGFF5KE3MA461154

2021 Mercedes-Benz GLS
450 4MATIC
76,976 mi
$32,127
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 175 currently listed for sale and an average price of $56,234, 28.6% of 2022 Mercedes-Benz GLS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
84.6% of 2022 Mercedes-Benz GLS listings on CarGurus are accident free.
Why it stands out
The 2022 Mercedes-Benz GLS sits at the top of Mercedes’ luxury SUV range and is the brand’s biggest SUV. As the SUV equivalent of the S-Class sedan, it is positioned as Mercedes’ flagship utility vehicle, and that role comes through in its emphasis on size, luxury, and practicality. It is also a three-row SUV, which helps make it appealing to buyers who want a full-size luxury model with real passenger and cargo utility.
For 2022, Mercedes withdrew most of its V8 models from the United States, leaving only the base six-cylinder GLS 450 4Matic model. That makes this model year notable for being simpler than the broader GLS lineup, while still offering the upscale presence and spaciousness expected from the nameplate. The available test-drive feedback points to stylish design, a powerful engine, and a roomy cabin as key strengths.
There are tradeoffs, though. The same test-drive data calls out poor ride quality, notes that advanced safety features are not standard, and flags poor ergonomic design. Even so, the 2022 Mercedes-Benz GLS remains distinctive as a large, luxurious, three-row SUV that combines flagship status with everyday usefulness.
Other model years to consider
- 2024 Mercedes-Benz GLS
- Average price: $81,134
- Good/great deal percentage: 38.4%
- User rating: 5 / 5
- Total listings: 219
- 2025 Mercedes-Benz GLS
- Average price: $64,626
- Good/great deal percentage: 37.6%
- Total listings: 218
- 2020 Mercedes-Benz GLS
- Average price: $29,663
- Good/great deal percentage: 33.9%
- User rating: 5 / 5
- Total listings: 180
Similar models to consider
- 2022 BMW X7
- Average price: $51,528
- Good/great deal percentage: 43.2%
- User rating: 5 / 5
- Total listings: 192
- 2022 Audi Q7
- Average price: $29,700
- Good/great deal percentage: 50.2%
- User rating: 5 / 5
- Total listings: 203
- 2022 Land Rover Range Rover
- Average price: $47,741
- Good/great deal percentage: 29.5%
- User rating: 5 / 5
- Total listings: 258
This analysis is based on CarGurus' proprietary market data from October 5, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
See more price trends2022 Mercedes-Benz GLS Pricing Analysis: Pittsburgh, PA Market Report
Pricing in Nearby Cities
Market Area: Pittsburgh, PA
Key Insights
- Highest-Price Market: The Youngstown, OH market leads with an average price of $112,995, indicating a premium demand in this area.
- Best Value: The Greensburg, PA market offers the lowest average price at $56,234, presenting a significant opportunity for budget-conscious shoppers.
- Inventory Drives Stability: With 182 total listings, Youngstown, OH not only has the highest prices but also the most robust inventory, suggesting a stable market presence.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Youngstown, OH | 182 | $112,995 |
| Greensburg, PA | 179 | $56,234 |
| Akron, OH | 179 | $112,995 |
| Boyers, PA | 172 | $56,234 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 450 4MATIC trim dominates with 406 listings, reflecting its popularity among consumers.
- Premium Spread: The AMG GLS 63 4MATIC trim has the highest MSRP at $135,400, showcasing a significant price range within the model.
- Drivetrain Effect: All trims feature AWD, indicating a consistent drivetrain preference among buyers, which may enhance resale value.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 406 | $77,850 | AWD | 3.0L 362 hp I6 |
| 580 4MATIC | 60 | $101,250 | AWD | 4.0L 483 hp V8 |
| AMG GLS 63 4MATIC | 70 | $135,400 | AWD | 4.0L 603 hp V8 |
| 600 Mercedes-Maybach 4MATIC | 62 | $165,100 | AWD | 4.0L 550 hp V8 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2026 model year shows a starting MSRP of $90,250, with an average price of $89,958, indicating minimal depreciation for new models.
- Depreciation Curve: The 2017 model year experiences the steepest depreciation at -73.9%, highlighting the rapid value loss typical for older luxury vehicles.
- Best Value Sweet Spot: The 2025 model year offers a significant average price drop of -19.1% from its MSRP, making it an attractive option for buyers seeking value.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2026 | $90,250 | $89,958 | -0.3% |
| 2025 | $89,200 | $72,140 | -19.1% |
| 2024 | $87,000 | $78,506 | -9.8% |
| 2023 | $81,800 | $53,880 | -34.1% |
| 2022 | $77,850 | $56,234 | -27.8% |
| 2021 | $76,000 | $32,509 | -57.2% |
| 2020 | $75,200 | $29,663 | -60.6% |
| 2019 | $70,150 | $19,951 | -71.6% |
| 2017 | $67,050 | $17,473 | -73.9% |
These recommendations are based on CarGurus' proprietary market data from October 7, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2022 Mercedes-Benz GLS cost?
| Metric | Value |
|---|---|
| Current Average Price | $46,509 |
| Year-Round Low | $46,509 |
| Year-Round High | $54,846 |
| Average Price a Year Ago | $54,850 |
| Change vs. Last Year | −15.21% |
Prices have softened 15.21% compared to this time last year, making it a favorable time to shop this model year.
There are 867 listings available, which gives you a decent amount of inventory to compare.
Is the 2022 Mercedes-Benz GLS a good car?
Yes — with a 5/5 user rating and a 7.33/10 expert rating, you’re looking at a model year that lands well with shoppers and our test-drive team alike. The 2022 GLS is positioned as Mercedes’ flagship SUV, and the overview emphasizes its size, luxury, and practicality as a three-row utility vehicle. The standout strength is Look and feel at 9/10.
The test-drive feedback backs that up with praise for its stylish design, powerful engine, and spacious cabin. The trade-offs are real, though: poor ride quality and poor ergonomic design are both called out, and advanced safety features are not standard.
For a buyer who wants a full-size luxury SUV with real passenger and cargo utility, the 2022 GLS fits the brief well. The market also shows 39.4% of listings are priced as good or great deals, which suggests there are opportunities if you shop carefully.
Is the 2022 Mercedes-Benz GLS reliable?
Owners rate it 5/5, a strong signal of long-term satisfaction.
The overview describes the 2022 GLS as a flagship utility vehicle with everyday usefulness, and the expert feedback supports that with a strong, smooth inline-six powertrain and standard air suspension. The performance notes also say the six-cylinder engine provides more than enough muscle for this big SUV, while the mild-hybrid assist is blended in nicely.
Mercedes’ cost-effectiveness notes add that the GLS comes with a four-year, 50,000-mile basic warranty and a four-year, 50,000-mile powertrain warranty. That helps reduce early ownership risk, but the model’s size, complexity, and optional equipment can still make used ownership more expensive if you need repairs or maintenance outside warranty coverage.
What should I look for when buying a used 2022 Mercedes-Benz GLS?
Accident-free inventory is solid at 87.3% — always verify the vehicle history report.
You should still run a history report on any candidate, even if it looks clean on paper. A pre-purchase inspection is especially important on a large luxury SUV like this, where suspension, electronics, and interior wear can matter a lot. Focus on overall condition, because the GLS is meant to deliver flagship comfort and utility, and neglected examples can be costly to bring back up to standard.
Key things to evaluate:
- Trim level: In base GLS 450 form, the cabin is described as fairly basic by GLS standards, and the test car lacked reclining seats. Even so, it still felt properly luxurious thanks to leather upholstery, a panoramic roof, ambient lighting, and a high-quality interior presentation.
- Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline six-cylinder engine with a nine-speed automatic and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft available in short bursts.
- Safety package: Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features cost extra.
- Infotainment: The standard MBUX setup includes a 12.3-inch touchscreen, 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM satellite radio, and natural-language voice recognition.
- Fuel efficiency: EPA ratings are 20 mpg combined (18 mpg city, 24 mpg highway).
Which 2022 Mercedes-Benz GLS trim should I buy?
The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.
Here's the short version:
The GLS 450 4Matic is the only standard gas-model choice for this year, so your decision is less about trim shopping and more about finding the right example. It brings the core GLS experience: a strong inline-six, standard AWD, air suspension, a surround-view camera system, and a well-appointed luxury cabin. It’s the best-value choice by default because there isn’t a broader trim ladder to climb for the 2022 model year.
Mercedes says some advanced safety features remain optional, so check carefully for adaptive cruise control, lane-keep assist, and second-row side airbags if those matter to you.
Is now a good time to buy a used 2022 Mercedes-Benz GLS?
This is a moderate market for selective buyers, with enough inventory to shop around but still enough demand to reward quick action on the right listing.
- Deal availability: 39.4% of listings are priced as good or great deals.
- Inventory: There are 867 listings available.
- Price trend: Prices have softened 15.21% compared with last year.
- Clean inventory: 87.3% of listings are accident-free.
If you find a listing below $46,509, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2022 Mercedes-Benz GLS's resale value?
The current average of $46,509 sits slightly below last year's $54,850.
That price movement suggests the market has already adjusted downward, which can help you buy at a more favorable point in the cycle. For a future seller, that also means resale value may depend heavily on condition, mileage, and equipment rather than model-year timing alone.
Because the GLS is a flagship luxury SUV with strong utility and broad appeal, well-kept examples should remain attractive to shoppers who want space and prestige in one package. Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.
Is the 2022 Mercedes-Benz GLS safe?
The 2022 Mercedes-Benz GLS does not have published IIHS or NHTSA crash-test ratings in the available data.
It earns a 6/10 safety score from our experts.
Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also includes a feature that can warn if it’s unsafe to open a door when parked.
The main caveat is that several advanced driver-assistance features are not standard, including adaptive cruise control, lane-keep assist, and second-row side airbags. That means you should check the equipment list carefully if safety tech is a priority for you.
Should I buy a 2022 Mercedes-Benz GLS or consider a different year?
If you're weighing the 2022 against nearby model years, here's how to think about it:
Choose the 2022 if:
- 39.4% of listings are priced as good or great deals.
- Accident-free inventory is solid at 87.3% — always verify the vehicle history report.
- Price trend: Prices have softened 15.21% compared with last year.
- Owners rate it 5/5 — a strong satisfaction signal.
- The year stands out for being simplified to the base six-cylinder GLS 450 4Matic, while still delivering flagship-size luxury and practicality.
Consider the 2021 if:
- At $45,941, the 2021 costs less than the current year's $46,509 average.
- The 2021 emphasizes S-Class-style refinement in a spacious three-row package.
The bottom line: If you want the simplest path into a 2022 GLS, this year makes sense because it still delivers the flagship SUV experience with strong satisfaction and a softer price trend. If you’re focused mainly on saving money, the 2021 is the better value play, especially if you find one in excellent condition.
These recommendations are based on CarGurus' proprietary market data from October 6, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
Relevant articles

The Best Large SUVs for Gas Mileage in 2026
Large SUVs and great gas mileage don't tend to go hand-in-hand. That said, some models are more impressive than others. Here are our favourites, including the BMW X7 and Chevrolet Tahoe.

The Best New Cars for Old Money Style in 2026
Whether you’re looking for something classic and timeless or you just want a nice vehicle that doesn’t project extreme affluence, there are a lot of new vehicles on the market today that feel luxurious, look elegant, yet don’t attract much attention.

The Best Luxury SUVs with 3 Rows in 2026
Luxury three-row SUVs provide extra seating without sacrificing elegance or amenities. These are the CarGurus Editorial team's picks for vehicles that can transport multiple passengers in style.