Used 2022 Mercedes-Benz GLS for Sale Nationwide
1,053 results
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 40,337
- Stock #:
- 57152W
- VIN:
- 4JGFF5KE9MA434606

2021 Mercedes-Benz GLS
450 4MATIC
40,337 mi
$38,670
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,900
- Stock #:
- MA575387
- VIN:
- 4JGFF8KE2MA575387

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
43,900 mi
$68,020
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 42,201
- Stock #:
- M3805B
- VIN:
- 4JGFF5KE9NA589433

2022 Mercedes-Benz GLS
450 4MATIC
42,201 mi
$48,094
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 26,550
- Stock #:
- CMTP230324
- VIN:
- 4JGFF5KE3PA973582

-$5,253
2023 Mercedes-Benz GLS
450 4MATIC
26,550 mi
$62,252
$56,999
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 80,263
- Stock #:
- M18387A
- VIN:
- 4JGFF8KE4MA461651

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
80,263 mi
$50,953
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,848
- Stock #:
- 9432HU
- VIN:
- 4JGFF5KE2NA755842

2022 Mercedes-Benz GLS
450 4MATIC
23,848 mi
$51,292
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,627
- Stock #:
- APA978637
- VIN:
- 4JGFF5KE5PA978637

2023 Mercedes-Benz GLS
450 4MATIC
23,627 mi
$60,702
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 82,501
- Stock #:
- A655836
- VIN:
- 4JGFF5KE0NA655836

2022 Mercedes-Benz GLS
450 4MATIC
82,501 mi
$35,067
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 68,075
- Stock #:
- VD4393A
- VIN:
- 4JGFF5KE9NA680914

2022 Mercedes-Benz GLS
450 4MATIC
68,075 mi
$42,900
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- Automatic
- Mileage:
- 37,445
- Stock #:
- TH35292A
- VIN:
- 4JGFF5KE0PA957663

2023 Mercedes-Benz GLS
450 4MATIC
37,445 mi
$57,789
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Manufaktur Diamond White Bright
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige Black)
- Transmission:
- 9-Speed Automatic Overdrive
- Mileage:
- 81,950
- Stock #:
- LS068622A
- VIN:
- 4JGFF8GE1NA767765

-$7,500
2022 Mercedes-Benz GLS
580 4MATIC
81,950 mi
$51,085
$43,585
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,929
- Stock #:
- JP74044
- VIN:
- 4JGFF5KE0PA969554

-$2,400
2023 Mercedes-Benz GLS
450 4MATIC
36,929 mi
$56,100
$53,700
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,443
- Stock #:
- 5449295
- VIN:
- 4JGFF5KE2NA738006

2022 Mercedes-Benz GLS
450 4MATIC
43,443 mi
$48,716
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 1,045 currently listed for sale and an average price of $49,893.00, 34.3% of 2022 Mercedes-Benz GLS for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars.
86.3% of 2022 GLS models on CarGurus are accident free.
The 2022 Mercedes-Benz GLS features a luxurious interior with ample space, a powerful turbocharged inline-six engine, and advanced tech including a dual-screen setup for the infotainment system.
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 51,152
- Stock #:
- NA710428
- VIN:
- 4JGFF5KE9NA710428

2022 Mercedes-Benz GLS
450 4MATIC
51,152 mi
$47,750
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 80,363
- Stock #:
- CC260152A
- VIN:
- 4JGFF5KE3MA442104

2021 Mercedes-Benz GLS
450 4MATIC
80,363 mi
$34,098
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 74,161
- Stock #:
- 2000879
- VIN:
- 4JGFF5KEXMA402750

-$1,000
2021 Mercedes-Benz GLS
450 4MATIC
74,161 mi
$35,500
$34,500
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Polar White
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 66,119
- Stock #:
- 260133A
- VIN:
- 4JGFF8KE2MA433444

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
66,119 mi
$62,636
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige / Black MB-Tex)
- Transmission:
- Automatic
- Mileage:
- 33,552
- Stock #:
- U1973T
- VIN:
- 4JGFF5KE4NA779219

2022 Mercedes-Benz GLS
450 4MATIC
33,552 mi
$49,249
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 72,815
- Stock #:
- PF8419A
- VIN:
- 4JGFF5KEXNA635030

-$2,000
2022 Mercedes-Benz GLS
450 4MATIC
72,815 mi
$40,399
$38,399
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,052
- Stock #:
- P3173
- VIN:
- 4JGFF5KE6NA774345
2022 Mercedes-Benz GLS
450 4MATIC
55,052 mi
$47,194
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 41,285
- Stock #:
- CPA928347
- VIN:
- 4JGFF5KEXPA928347

2023 Mercedes-Benz GLS
450 4MATIC
41,285 mi
$58,925
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 26,750
- Stock #:
- NA690694
- VIN:
- 4JGFF5KE5NA690694

-$1,989
2022 Mercedes-Benz GLS
450 4MATIC
26,750 mi
$51,982
$49,993
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 61,789
- Stock #:
- MA369497
- VIN:
- 4JGFF5KE0MA369497

2021 Mercedes-Benz GLS
450 4MATIC
61,789 mi
$38,294
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 1,045 currently listed for sale and an average price of $49,893.00, 34.3% of 2022 Mercedes-Benz GLS for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars.
86.3% of 2022 GLS models on CarGurus are accident free.
The 2022 Mercedes-Benz GLS features a luxurious interior with ample space, a powerful turbocharged inline-six engine, and advanced tech including a dual-screen setup for the infotainment system.
Why it stands out
The 2022 Mercedes-Benz GLS distinguishes itself as a premier luxury SUV that combines expansive space with high-end amenities. This model serves as the flagship of the Mercedes SUV lineup, noted for its spacious three-row configuration that comfortably seats seven. With its robust 3.0-liter turbocharged inline-six engine delivering 362 horsepower, the GLS provides ample performance while maintaining a smooth ride. The luxury interior is laden with high-quality materials and cutting-edge technology, including the standard MBUX infotainment system featuring a 12.3-inch touchscreen. Despite its grandeur, some users have noted ergonomic shortcomings and a less-than-ideal ride quality compared to competitors. Nevertheless, the GLS remains a compelling choice for those seeking a blend of luxury, versatility, and technology in their full-size SUV.
Other model years to consider
- Average price: $75,988.00
- Good/great deal percentage: 34.2%
- User rating: 5 / 5
- Total listings: 1,445
- Average price: $69,671.00
- Good/great deal percentage: 34.6%
- Accident-free percentage: 90.0%
- Total listings: 1,322
- Average price: $34,925.00
- Good/great deal percentage: 35.5%
- User rating: 5 / 5
- Total listings: 801
This analysis is based on CarGurus' proprietary market data from June 15, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

The Best Large SUVs for Gas Mileage in 2026
Large SUVs and great gas mileage don't tend to go hand-in-hand. That said, some models are more impressive than others. Here are our favourites, including the BMW X7 and Chevrolet Tahoe.

The Best New Cars for Old Money Style in 2026
Whether you’re looking for something classic and timeless or you just want a nice vehicle that doesn’t project extreme affluence, there are a lot of new vehicles on the market today that feel luxurious, look elegant, yet don’t attract much attention.

Mercedes-Benz GLS Buying Guide: Cost, Reliability, and the Best Years to Buy
Discover the ultimate buying guide for purchasing a used Mercedes-Benz GLS covering each generation since 2017. Whether you're a first-time buyer or a Mercedes enthusiast, this comprehensive overview will help you research your next pre-owned Mercedes-Benz GLS.
5.0 Overall rating
Filter by rating
rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
See more price trends