Used 2022 Mercedes-Benz GLS for Sale nearChicago, IL

How much does the 2022 Mercedes-Benz GLS cost?

Prices have softened 14.84% compared to this time last year, making it a favorable time to shop this model year.

There are 861 listings available, which suggests you should have a workable range of choices.

Is the 2022 Mercedes-Benz GLS a good car?

Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.33/10 expert rating. The standout strength is Look and feel at 9/10.

The GLS is positioned as Mercedes’ flagship SUV, so you’re shopping for a full-size luxury statement rather than a simple family hauler. The overview and test-drive notes both point to a stylish design, a powerful engine, and a spacious cabin, which fit that role well.

The trade-offs are worth weighing: poor ride quality and poor ergonomic design show up in the expert notes, and advanced safety features are not standard. If you want a large, upscale SUV with a strong presence and room to spare, the GLS fits that use case well.

37.2% of listings are priced as good or great deals, so there is some room to shop selectively.

Is the 2022 Mercedes-Benz GLS reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The GLS is described as a luxury SUV with a strong emphasis on comfort, utility, and upscale presentation, and the expert notes also highlight a smooth inline-six layout that suits a luxury vehicle. The mild-hybrid setup is presented as helping with start/stop behavior and reducing engine workload, which supports everyday drivability.

Mercedes also notes that the electric motor powers most accessories, which can help ease the engine’s burden in normal use. For used buyers, the main long-term ownership risk is that a large, complex luxury SUV can become expensive if prior maintenance or repairs were neglected.

What should I look for when buying a used 2022 Mercedes-Benz GLS?

Accident-free inventory is solid at 86.9% — always verify the vehicle history report.

You should still check the vehicle history report carefully, even when the market looks clean overall. A pre-purchase inspection should focus on ride quality, interior ergonomics, and any signs that the vehicle has been used hard or maintained inconsistently. It also makes sense to confirm which convenience and driver-assistance features are actually installed, since some important items were optional.

Key things to evaluate:

• Trim level: The base GLS 450 form is described as more subtle and less flashy than some rivals, and the test car’s fairly basic interior lacked reclining seats. That means you should pay close attention to whether the example you’re considering has the comfort and luxury equipment you want.
• Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline six-cylinder engine with a nine-speed automatic transmission and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft available in short bursts.
• Safety package: Standard equipment includes forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features are extra.
• Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM satellite radio, and natural-language voice recognition. A head-up display is optional.
• Fuel efficiency: EPA fuel economy is 20 mpg combined (18 mpg city, 24 mpg highway).

Which 2022 Mercedes-Benz GLS trim should I buy?

The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.

Here's the short version:

The GLS 450 4Matic is the only version available for this model year in the provided data, so your decision is really about finding the right example rather than choosing between trims. It brings the core GLS strengths: a powerful inline-six, standard AWD, standard air suspension, and a well-equipped MBUX cabin.

The best-value path is to focus on a clean, well-optioned GLS 450 4Matic with the comfort and safety features you care about most, since some key items remain optional. Safety-package gaps are important here: adaptive cruise control, lane-keep assist, second-row side airbags, and other advanced driver-assistance features are not standard.

Is now a good time to buy a used 2022 Mercedes-Benz GLS?

This looks like a moderate, selective buyer’s market, so you can shop with some leverage if you stay patient.

• Deal availability: 37.2% of listings are priced as good or great deals.
• Inventory: There are 861 listings available.
• Price trend: Prices have softened 14.84% compared with last year.
• Clean inventory: 86.9% of listings are accident-free.

If you find a listing below $47,558, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz GLS's resale value?

The current average of $47,558 sits slightly below last year's $55,844.

That decline suggests the market has already adjusted downward, which can help you buy at a more favorable entry point. For a future seller, it also means you should expect resale value to depend heavily on condition, mileage, and equipment rather than on broad market momentum alone.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz GLS safe?

It earns a 6/10 safety score from our experts.

Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also includes a system that can warn if it’s unsafe to open a door when parked.

You should note that adaptive cruise control, lane-keep assist, second-row side airbags, and several more advanced driver-assistance features are optional rather than standard. That means you’ll want to verify the exact equipment on any used example you’re considering.

Should I buy a 2022 Mercedes-Benz GLS or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 37.2% of listings are priced as good or great deals.
• Accident-free inventory is solid at 86.9% — always verify the vehicle history report.
• Price trend: Prices have softened 14.84% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• Mercedes withdrew most V8 models for this year, leaving the GLS 450 as the only version available at the time of testing.

Consider the 2021 if:

• At $47,795, the 2021 costs more than the current year's $47,558 average.
• It emphasizes comfort above all else.

The bottom line: If you want the better current-market value, the 2022 is the cleaner buy because prices have eased and inventory is available. If you’re mainly comparing on price, the 2021 does not offer a lower average entry point here, so the 2022 is the more compelling starting point unless you find a particularly strong 2021 example.

These recommendations are based on CarGurus' proprietary market data from September 15, 2026, CarGurus experts' opinions, and generative AI.