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Used 2022 Lexus RX for Sale near Durham, NC

163 results
Durham, NC
2023 Lexus RX 350 Luxury FWD Hanna Infiniti of Apex

2023 Lexus RX

350 Luxury FWD

32,330 miles

$47,999

Fair Deal
Apex, NC
17 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red (Copper Crest)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
32,330
Stock number:
6000360
VIN:
2T2BAMBA5PC022364

Sponsored

2023 Lexus RX 350 FWD

2023 Lexus RX

350 FWD

12,614 miles

$46,988

Great Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
12,614
Stock number:
DP11277
VIN:
JTJCHMAA2P2002154

Sponsored

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

37,104 miles

$44,488

Fair Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
37,104
Stock number:
DP11404
VIN:
2T2YZMDA9NC344793

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

19,953 miles

$40,997

Good Deal
Store transfer to Raleigh, NC
2,156 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
19,953
Stock number:
28087598
VIN:
2T2HZMAA2NC250629

2022 Lexus RX 350L FWD

2022 Lexus RX

350L FWD

29,735 miles

$42,218

Fair Deal
Henderson, NC
35 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel
Transmission:
Automatic
Mileage:
29,735
Stock number:
T712A
VIN:
JTJHZKEA2N2024265

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

53,291 miles

$40,378

Great Deal
Certified Pre-Owned
Raleigh, NC
20 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
53,291
Stock number:
P12231
VIN:
2T2YZMDA5NC353782

Preparing for a close up...

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2021 Lexus RX

350 FWD

69,114 miles

$30,997

Great Deal
Store transfer to Raleigh, NC
2,223 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Blue
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
69,114
Stock number:
27676202
VIN:
2T2AZMAA4MC200508

Preparing for a close up...

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2021 Lexus RX

350 FWD

45,561 miles

$32,897

Good Deal
Cary, NC
19 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (Tan)
Transmission:
Automatic
Mileage:
45,561
Stock number:
CMC197109
VIN:
2T2AZMAA6MC197109

Preparing for a close up...

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2023 Lexus RX

350 Luxury FWD

20,911 miles

$48,488

Great Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red (Copper Crest)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
20,911
Stock number:
DP11163
VIN:
2T2BAMBA9PC019614

Preparing for a close up...

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2023 Lexus RX

350 Premium AWD

34,573 miles

$44,997

Good Deal
Cary, NC
19 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
Automatic
Mileage:
34,573
Stock number:
PPC017492
VIN:
2T2BAMCA2PC017492

Preparing for a close up...

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2023 Lexus RX

350 Premium FWD

20,478 miles

$42,700

Great Deal
Raleigh, NC
20 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
20,478
Stock number:
3022951
VIN:
2T2BAMBA6PC011504

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 FWD

12,614 miles

$46,988

Great Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
12,614
Stock number:
DP11277
VIN:
JTJCHMAA2P2002154

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport FWD

41,267 miles

$35,700

Great Deal
Raleigh, NC
20 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
41,267
Stock number:
3023175
VIN:
2T2SZMAA1MC196387

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium FWD

46,414 miles

$41,488

Great Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nightfall Mica
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
46,414
Stock number:
DP11182
VIN:
2T2BAMBA1PC008090

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 F Sport Handling AWD

13,534 miles

$50,988

Good Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nightfall Mica
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
13,534
Stock number:
DP11354
VIN:
2T2BAMCA3PC038514

Preparing for a close up...

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2023 Lexus RX

350 Premium FWD

23,737 miles

$42,400

Great Deal
Raleigh, NC
20 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Macadamia
Transmission:
8-Speed Automatic
Mileage:
23,737
Stock number:
3022956
VIN:
JTJCHMAA6P2008586

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350L Luxury FWD

51,370 miles

$42,988

Fair Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
51,370
Stock number:
D93621A
VIN:
JTJJZKEA1N2028888

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

37,104 miles

$44,488

Fair Deal
Certified Pre-Owned
Durham, NC
7 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
37,104
Stock number:
DP11404
VIN:
2T2YZMDA9NC344793

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

19,752 miles

$42,862

Fair Deal
Apex, NC
17 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
19,752
Stock number:
6000376
VIN:
2T2HZMAA9NC231897

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

42,433 miles

$38,500

Great Deal
Sanford, NC
39 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
42,433
Stock number:
7006126
VIN:
2T2YZMDA2NC349110

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Luxury FWD

27,348 miles

$46,300

Great Deal
Raleigh, NC
20 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red (Copper Crest)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
27,348
Stock number:
3022112
VIN:
2T2BAMBA3PC001626

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / North Carolina
  6. / Durham
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX

Summary

  • With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
  • 84.2% of 2022 RX models on CarGurus are accident free.
  • The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Durham, NC?

The average 2022 Lexus RX costs about $40,378.40. The average price has decreased by -4.7% since last year. The 163 for sale near Durham, NC on CarGurus, range from $26,940 to $56,192 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Durham, NC have no reported accidents or damage?

163 out of 163 for sale near Durham, NC have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or MPGe).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Durham NC

  • 2024 Lexus RX

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  • 2021 Lexus RX

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  • 2019 Lexus RX in Durham NC

  • Lexus RX 350 FWD

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  • Lexus RX 350 F Sport Handling AWD in Durham NC

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  • Johnson Lexus of Durham at Southpoint

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