Used 2022 Lexus ES for Sale near Des Moines, IA
53 results
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Chateau
- Transmission:
- 8-Speed Automatic
- Mileage:
- 14,007
- Stock #:
- KB7266
- VIN:
- 58AD11D13MU007647


Sponsored by Shottenkirk Chevrolet Waukee
2021 Lexus ES
250 AWD
14,007 mi
$36,816
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Acorn
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,033
- Stock #:
- TJ285862I
- VIN:
- 58AEZ1B15PU147719

Sponsored Listing
2023 Lexus ES
350 Luxury FWD
25,033 mi
$43,475
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Chateau
- Transmission:
- 8-Speed Automatic
- Mileage:
- 54,275
- Stock #:
- L26RX687D
- VIN:
- 58AD11D15MU006788

2021 Lexus ES
250 AWD
54,275 mi
$31,900
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- CREAM
- Transmission:
- Automatic
- Mileage:
- 49,026
- Stock #:
- 70010207
- VIN:
- 58AJZ1B1XNU127669

2022 Lexus ES
350 F Sport FWD
49,026 mi
$37,747
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- CREAM
- Transmission:
- Automatic
- Mileage:
- 33,416
- Stock #:
- 70069803
- VIN:
- 58AJZ1B1XPU159069

2023 Lexus ES
350 F Sport Handling FWD
33,416 mi
$40,497
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 16,215
- Stock #:
- 28727500
- VIN:
- 58AD11D15PU011090

2023 Lexus ES
250 AWD
16,215 mi
$37,697
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Acorn
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,033
- Stock #:
- TJ285862I
- VIN:
- 58AEZ1B15PU147719

2023 Lexus ES
350 Luxury FWD
25,033 mi
$43,475
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Flaxen w/Linear Espresso Wood Trim)
- Transmission:
- Automatic
- Mileage:
- 86,906
- Stock #:
- DV13620
- VIN:
- 58ADZ1B11MU092564

-$811
2021 Lexus ES
350 FWD
86,906 mi
$28,968
$28,157
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Chateau
- Transmission:
- 8-Speed Automatic
- Mileage:
- 14,007
- Stock #:
- KB7266
- VIN:
- 58AD11D13MU007647

2021 Lexus ES
250 AWD
14,007 mi
$36,816
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 76,466
- Stock #:
- 70047846
- VIN:
- 58ADZ1B15PU144878

2023 Lexus ES
350 FWD
76,466 mi
$35,397
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 18,316
- Stock #:
- 70063802
- VIN:
- 58ADZ1B16PU142007

2023 Lexus ES
350 FWD
18,316 mi
$41,597
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 22,074
- Stock #:
- 70069940
- VIN:
- 58ACZ1B12PU152450

2023 Lexus ES
350 FWD
22,074 mi
$38,497
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rich Creme
- Transmission:
- 8-Speed Automatic
- Mileage:
- 41,968
- Stock #:
- NU135876
- VIN:
- 58ADZ1B14NU135876

2022 Lexus ES
350 FWD
41,968 mi
$34,920
CarGurus Analysis:
2022 Lexus ES
With 757 currently listed for sale and an average price of $35,792.00, 32.6% of 2022 Lexus ES models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus ES 5 / 5 stars.
80.2% of 2022 Lexus ES models on CarGurus are accident free.
The 2022 Lexus ES offers multiple powertrain options, including a fuel-efficient hybrid variant, a quiet cabin, and numerous innovative features, making it an ideal choice for luxury sedan buyers.
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Hadori Aluminum
- Transmission:
- 8-Speed Automatic
- Mileage:
- 59,278
- Stock #:
- R5444XR
- VIN:
- 58AGZ1B14NU125099

2022 Lexus ES
350 F Sport FWD
59,278 mi
$39,024
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 69,890
- Stock #:
- 70043926
- VIN:
- 58AJZ1B16NU132772

2022 Lexus ES
350 F Sport FWD
69,890 mi
$35,747
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 16,853
- Stock #:
- TSK1382
- VIN:
- 58ACZ1B11NU129917

2022 Lexus ES
350 FWD
16,853 mi
$39,303
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 37,757
- Stock #:
- 144880
- VIN:
- 58AJZ1B1XPU144880

2023 Lexus ES
350 F Sport Handling FWD
37,757 mi
$42,072
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- 8-Speed Automatic
- Mileage:
- 14,094
- Stock #:
- 116994
- VIN:
- 58ADZ1B13NU116994

2022 Lexus ES
350 FWD
14,094 mi
$39,438
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rich Creme
- Transmission:
- 8-Speed Automatic
- Mileage:
- 82,751
- Stock #:
- 1047987
- VIN:
- 58ADZ1B1XMU110866

2021 Lexus ES
350 FWD
82,751 mi
$28,186
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Brown (Beige)
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 69,733
- Stock #:
- 6359A
- VIN:
- 58AD11D19MU004669

2021 Lexus ES
250 AWD
69,733 mi
$29,735
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Sunlit Green
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Linear Espresso Wood Trim
- Transmission:
- 8-Speed Automatic
- Mileage:
- 68,691
- Stock #:
- MU002456
- VIN:
- 58AD11D14MU002456

2021 Lexus ES
250 AWD
68,691 mi
$30,611
- Year:
- 2023
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 24,489
- Stock #:
- U143776
- VIN:
- 58ADZ1B13PU143776

2023 Lexus ES
350 FWD
24,489 mi
$37,342
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rich Creme
- Transmission:
- 8-Speed Automatic
- Mileage:
- 98,328
- Stock #:
- X116664
- VIN:
- 58ADZ1B14NU116664

2022 Lexus ES
350 FWD
98,328 mi
$29,981
CarGurus Analysis: 2022 Lexus ES
overall

Summary
With 757 currently listed for sale and an average price of $35,792.00, 32.6% of 2022 Lexus ES models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus ES 5 / 5 stars.
80.2% of 2022 Lexus ES models on CarGurus are accident free.
The 2022 Lexus ES offers multiple powertrain options, including a fuel-efficient hybrid variant, a quiet cabin, and numerous innovative features, making it an ideal choice for luxury sedan buyers.
Why it stands out
The 2022 Lexus ES stands out in the luxury sedan segment due to its blend of comfort, performance, and safety features. With a strong emphasis on a smooth, quiet ride, it caters to buyers looking for a relaxing driving experience. The available four-cylinder, six-cylinder, and hybrid powertrains provide flexibility according to driver preferences, while maintaining excellent fuel efficiency. Although some drivers may find the styling uninspired and performance fairly pedestrian when compared to its rivals, the extensive safety suite, including Lexus Safety System+ 2.5, enhances its appeal for safety-conscious buyers. The ES is particularly well-rated for its well-appointed interior and advanced technology, making it a competitive option against more expensive rivals.
Other model years to consider
- Average price: $29,707.00
- Good/great deal percentage: 33.4%
- User rating: 5 / 5
- Total listings: 664
- Average price: $15,090.00
- Good/great deal percentage: 33.1%
- User rating: 4.78 / 5
- Total listings: 496
- Average price: $19,852.00
- Good/great deal percentage: 34.5%
- User rating: 4.5 / 5
- Total listings: 586
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

Lexus ES Buying Guide: Cost, Reliability, and the Best Years to Buy
Our definitive Lexus ES buying guide has the full lowdown on the eight model generations available, including details of how much you can expect to pay for one, and which are the best and worst versions to buy.

The Best Affordable Luxury Cars in 2026
There are plenty of great options for affordable new luxury cars, if you know where to look. Our expert guide gives you the lowdown on the best cheap luxury cars you can buy.

The Most Reliable Luxury Cars of 2026
Luxury cars give you the best of most things but which are the most reliable luxury cars you can buy? Our guide has all the details.
5.0 Overall rating
Filter by rating
Selena S
Reviewed a 2022 Lexus 350 F Sport FWD on Mar 9, 2025
Great car with the best innovation. Most reliable care with more bang for the buck.
Ashley F
Reviewed a 2022 Lexus 350 F Sport FWD on Oct 31, 2024
IS 350 with the space of an ES 350. CarPlay still needs to be connected to USB for connection (not very 2022 energy). Rides so smoothly!
Mike S
Reviewed a 2022 Lexus 350 Ultra Luxury FWD on Jul 15, 2025
Great ultra luxury car. A bit small but good. Just made a road trip and the car behave very good. Like it too much.
Mark D
Reviewed a 2022 Lexus ES on Jul 27, 2023
The lexus ES 350 rides really nice,7412miles so its practically a new car,really cool features safety is my #1 issue so this the car for me,and reliable is also a major factor thats why I chose this model
2022 Lexus ES Trims
| Trim type | MSRP |
|---|---|
| 250 AWD | $40,950 |
| 250 F Sport AWD | $45,600 |
| 250 Luxury AWD | $46,350 |
| 350 F Sport FWD | $45,600 |
| 350 FWD | $40,950 |
| 350 Luxury FWD | $46,350 |
| 350 Ultra Luxury FWD | $50,130 |
| 250 Ultra Luxury AWD | $50,130 |
2022 Lexus ES Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus ES prices has changed over time.
See more price trends