Used 2021 Mercedes-Benz E-Class for Sale near Vienna, IL
125 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 905 currently listed for sale and an average price of $39,487.00, 24.6% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
76.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class received a mid-cycle update with enhancements to the infotainment system, engines, and exterior styling, providing an impressively luxurious driving experience.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 905 currently listed for sale and an average price of $39,487.00, 24.6% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
76.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class received a mid-cycle update with enhancements to the infotainment system, engines, and exterior styling, providing an impressively luxurious driving experience.
Why it stands out
The 2021 Mercedes-Benz E-Class distinguishes itself in the luxury midsize sedan segment through an exceptional blend of performance, comfort, and cutting-edge technology. With multiple powertrain options, including an electrified inline-six for the E450, the E-Class caters to a variety of driving preferences—delivering both power and efficiency. The refined interior, adorned with high-quality materials and state-of-the-art MBUX infotainment, creates an inviting atmosphere. Expert reviews highlight its superior ride quality and advanced technology, with an impressive score of 8.33 out of 10 in expert assessments. While it excels in many areas, potential buyers should be mindful that advanced safety features are not standard, which slightly hinders its overall appeal. Nevertheless, the E-Class remains a practical choice for buyers seeking luxury without compromising performance.
Other model years to consider
- Average price: $41,903.00
- Good/great deal percentage: 25.6%
- User rating: 5 / 5
- Total listings: 1,078
- Average price: $18,833.00
- Good/great deal percentage: 28.2%
- User rating: 4.78 / 5
- Total listings: 1,367
- Average price: $23,614.00
- Good/great deal percentage: 26.5%
- User rating: 4.76 / 5
- Total listings: 1,401
This analysis is based on CarGurus' proprietary market data from April 20, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles
The Best Family Sedans of 2026
Advanced safety features that were once exclusive to luxury cars are now standard on many family sedans. And while sedans might not have the space of an SUV or a minivan, they do have efficiency on their side. Here are our top 10.
2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
See more price trends
