Used 2021 Mercedes-Benz E-Class for Sale near Milwaukee, WI
120 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 901 currently listed for sale and an average price of $39,193.00, 32.5% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.9% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class introduced a mid-cycle update, featuring improved infotainment, engine efficiency with hybrid powertrains, and elegant exterior styling.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 901 currently listed for sale and an average price of $39,193.00, 32.5% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.9% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class introduced a mid-cycle update, featuring improved infotainment, engine efficiency with hybrid powertrains, and elegant exterior styling.
Why it stands out
The 2021 Mercedes-Benz E-Class is distinguished by its luxurious blend of performance, advanced technology, and sophisticated design. It features multiple powertrain options, including new hybrid systems that enhance fuel efficiency without sacrificing performance. The contemporary aesthetics are complemented by a high-tech interior, highlighted by dual 12-inch screens, and premium materials that create an inviting atmosphere. While many owners appreciate the E-Class's ride quality and tech features, a few have expressed concerns about its high price point and the absence of certain advanced safety features as standard. Overall, it remains a top choice for those seeking a midsize luxury sedan that offers a mix of comfort, style, and capability.
Other model years to consider
- Average price: $30,396.00
- Good/great deal percentage: 33.1%
- User rating: 5 / 5
- Total listings: 1,016
- Average price: $41,560.00
- Good/great deal percentage: 32.3%
- User rating: 5 / 5
- Total listings: 1,082
- Average price: $23,345.00
- Good/great deal percentage: 32.3%
- User rating: 4.76 / 5
- Total listings: 1,430
This analysis is based on CarGurus' proprietary market data from May 4, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 Cabriolet RWD | $71,950 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| E 350 RWD | $54,250 |
| E 350 4MATIC | $56,750 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
See more price trends
