Used 2021 Lexus RX for Sale near Johnson City, TN
128 results
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 24,897
- Stock #:
- PC7130
- VIN:
- JTJHZKFA8N2040727
Sponsored by McNeill Chevrolet
2022 Lexus RX
350L AWD
24,897 mi
$46,655
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,311
- Stock #:
- ANC221620
- VIN:
- 2T2AZMAA2NC221620
-$746
Sponsored Listing
2022 Lexus RX
350 FWD
62,311 mi
$34,419
$33,673
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,644
- Stock #:
- C356A
- VIN:
- 2T2HZMAA6NC235163
Sponsored Listing
2022 Lexus RX
350 FWD
65,644 mi
$39,689
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 73,167
- Stock #:
- 28843229
- VIN:
- 2T2SZMDAXLC214508
2020 Lexus RX
350 F Sport AWD
73,167 mi
$35,147
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,929
- Stock #:
- 70066824
- VIN:
- 2T2AZMAAXLC159445
2020 Lexus RX
350 FWD
59,929 mi
$32,997
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,901
- Stock #:
- U4007
- VIN:
- 2T2HZMAA5NC256067
2022 Lexus RX
350 FWD
61,901 mi
$39,549
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 53,747
- Stock #:
- TNC354670
- VIN:
- 2T2YZMDAXNC354670
2022 Lexus RX
350 F Sport Handling AWD
53,747 mi
$40,697
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,212
- Stock #:
- P6813
- VIN:
- 2T2YZMDA9NC328335
2022 Lexus RX
350 F Sport Handling AWD
31,212 mi
$48,069
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 81,138
- Stock #:
- 104484A
- VIN:
- 2T2SZMDA9MC270666
2021 Lexus RX
350 F Sport AWD
81,138 mi
$32,701
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 44,920
- Stock #:
- Y6248
- VIN:
- JTJHZKFA0M2028490
2021 Lexus RX
350L AWD
44,920 mi
$39,994
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment w/Matte Bamboo Trim)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,361
- Stock #:
- 181996
- VIN:
- 2T2HZMAA5LC181996
2020 Lexus RX
350 FWD
52,361 mi
$35,324
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,190
- Stock #:
- LC165746A
- VIN:
- 2T2HZMAA1LC165746
2020 Lexus RX
350 FWD
62,190 mi
$35,154
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 43,681
- Stock #:
- P8224
- VIN:
- 2T2AZMAA0NC219297
2022 Lexus RX
350 FWD
43,681 mi
$43,282
CarGurus Analysis:
2021 Lexus RX
With 1,476 currently listed for sale and an average price of $36,336.00, 34.5% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars.
76.6% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX continues to impress with its luxurious features, comfortable driving experience, and notable tech upgrades for this model year, including enhanced standard safety systems.
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 75,513
- Stock #:
- U242309
- VIN:
- 2T2HZMDA9LC242309
2020 Lexus RX
350 AWD
75,513 mi
$34,284
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 62,498
- Stock #:
- U00996A
- VIN:
- 2T2YZMDA9NC348861
2022 Lexus RX
350 F Sport Handling AWD
62,498 mi
$44,679
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 24,829
- Stock #:
- MP11484
- VIN:
- 2T2JZMAA7NC222911
-$2,781
2022 Lexus RX
350 FWD
24,829 mi
$47,330
$44,548
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 92,587
- Stock #:
- MNC311577
- VIN:
- 2T2SZMDA6NC311577
2022 Lexus RX
350 F Sport AWD
92,587 mi
$32,734
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,340
- Stock #:
- LC253331
- VIN:
- 2T2HZMDA2LC253331
2020 Lexus RX
350 AWD
62,340 mi
$34,301
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,644
- Stock #:
- C356A
- VIN:
- 2T2HZMAA6NC235163
2022 Lexus RX
350 FWD
65,644 mi
$39,689
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,507
- Stock #:
- ND3597
- VIN:
- 2T2SZMDA9LC214287
2020 Lexus RX
350 F Sport AWD
62,507 mi
$36,267
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,311
- Stock #:
- ANC221620
- VIN:
- 2T2AZMAA2NC221620
-$746
2022 Lexus RX
350 FWD
62,311 mi
$34,419
$33,673
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 51,144
- Stock #:
- 249714
- VIN:
- 2T2HZMAAXNC249714
2022 Lexus RX
350 FWD
51,144 mi
$40,799
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 67,778
- Stock #:
- 26083A
- VIN:
- JTJHZKEA2N2027117
Sponsored Listing
2022 Lexus RX
350L FWD
67,778 mi
$40,188
CarGurus Analysis: 2021 Lexus RX
overall
Summary
With 1,476 currently listed for sale and an average price of $36,336.00, 34.5% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars.
76.6% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX continues to impress with its luxurious features, comfortable driving experience, and notable tech upgrades for this model year, including enhanced standard safety systems.
Why it stands out
The 2021 Lexus RX remains a formidable contender in the luxury SUV segment, blending comfort with a reputation for reliability. This model features a robust 3.5-liter V6 engine producing 295 horsepower, ensuring a smooth yet powerful driving experience. Enhancements for 2021 include improvements in safety technology, making this model even more appealing to buyers who value security alongside luxury. The intuitive design and high-quality interior materials elevate the driving experience, while its eye-catching exterior styling gives it a distinct presence on the road. Although some users have noted its limited cargo space as a downside, the RX compensates with plush seating and a smooth ride, making it an excellent choice for those prioritizing comfort and amenities over sheer performance.
Other model years to consider
- Average price: $47,487.00
- Good/great deal percentage: 37.5%
- User rating: 5 / 5
- Total listings: 3,359
- Average price: $50,787.00
- Good/great deal percentage: 37.6%
- User rating: 5 / 5
- Total listings: 3,290
- Average price: $41,038.00
- Good/great deal percentage: 37.0%
- User rating: 4.75 / 5
- Total listings: 2,586
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
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5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury FWD | $54,050 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport AWD | $50,100 |
| 350 F Sport Handling AWD | $52,500 |
| 350 AWD | $46,620 |
| 350 FWD | $45,220 |
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
See more price trends
