Used 2021 Lexus RX for Sale nearJohnson City, TN
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,798
- Stock #:
- 26046P
- VIN:
- 2T2HZMAA3MC185272


Sponsored by Wallace Kia of Bristol
2021 Lexus RX
350 FWD
49,798 mi
$37,689
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 117,172
- Stock #:
- ALC257931
- VIN:
- 2T2HZMDA2LC257931

Sponsored Listing
2020 Lexus RX
350 AWD
117,172 mi
$28,674
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 73,871
- Stock #:
- 19218000
- VIN:
- 2T2HZMAA3MC197535

Sponsored Listing
2021 Lexus RX
350 FWD
73,871 mi
$34,999
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 29,726
- Stock #:
- 29142435
- VIN:
- 2T2AZMDA9NC315991

2022 Lexus RX
350 AWD
29,726 mi
$40,147
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,901
- Stock #:
- U4007
- VIN:
- 2T2HZMAA5NC256067

2022 Lexus RX
350 FWD
61,901 mi
$36,800
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,610
- Stock #:
- 26CL46010B
- VIN:
- 2T2YZMDA0LC243316

2020 Lexus RX
350 F Sport Performance AWD
49,610 mi
$35,354
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 73,871
- Stock #:
- 19218000
- VIN:
- 2T2HZMAA3MC197535

2021 Lexus RX
350 FWD
73,871 mi
$34,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch w/Matte Walnut Trim
- Transmission:
- Automatic
- Mileage:
- 54,790
- Stock #:
- B26263A
- VIN:
- 2T2HZMAA8MC210764

2021 Lexus RX
350 FWD
54,790 mi
$36,314
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 42,869
- Stock #:
- M19300
- VIN:
- 2T2HZMDAXLC226491

2020 Lexus RX
350 AWD
42,869 mi
$34,991
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Brown (Moonbeam Beige Metallic)
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,748
- Stock #:
- T61025
- VIN:
- 2T2HZMAA0LC161025

2020 Lexus RX
350 FWD
61,748 mi
$34,762
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,798
- Stock #:
- 26046P
- VIN:
- 2T2HZMAA3MC185272

2021 Lexus RX
350 FWD
49,798 mi
$37,689
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 68,020
- Stock #:
- P26909
- VIN:
- 2T2HZMAA5LC158959

2020 Lexus RX
350 FWD
68,020 mi
$33,599
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- Automatic
- Mileage:
- 89,454
- Stock #:
- 153757
- VIN:
- 2T2HZMAA1LC153757

2020 Lexus RX
350 FWD
89,454 mi
$29,889
CarGurus Analysis:
2021 Lexus RX
With 1,498 currently listed for sale and an average price of $35,381, 36.2% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
74.2% of 2021 RX models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 44,649
- Stock #:
- YK6147B
- VIN:
- 2T2HZMAA5NC225059

2022 Lexus RX
350 FWD
44,649 mi
$41,352
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,852
- Stock #:
- PNC337161
- VIN:
- 2T2SZMDA6NC337161

2022 Lexus RX
350 F Sport AWD
46,852 mi
$39,576
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,677
- Stock #:
- 161094
- VIN:
- 2T2HZMAA8LC161094

2020 Lexus RX
350 FWD
49,677 mi
$34,528
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,447
- Stock #:
- R156
- VIN:
- 2T2HZMDA7LC256984

2020 Lexus RX
350 AWD
59,447 mi
$33,187
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,335
- Stock #:
- 66683
- VIN:
- 2T2HZMAA1MC189658

2021 Lexus RX
350 FWD
65,335 mi
$33,535
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,939
- Stock #:
- MC260028A
- VIN:
- 2T2YZMDA1MC260028

2021 Lexus RX
350 F Sport Handling AWD
49,939 mi
$40,154
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,997
- Stock #:
- 207994
- VIN:
- 2T2HZMAAXMC207994

2021 Lexus RX
350 FWD
48,997 mi
$32,762
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 92,571
- Stock #:
- 052771
- VIN:
- JTJHZMDA9M2052771

2021 Lexus RX
350 AWD
92,571 mi
$31,399
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- CREAM
- Transmission:
- Automatic
- Mileage:
- 26,664
- Stock #:
- 28925798
- VIN:
- 2T2HZMAA6NC255493

2022 Lexus RX
350 FWD
26,664 mi
$44,097
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 68,020
- Stock #:
- P26909
- VIN:
- 2T2HZMAA5LC158959

Sponsored Listing
2020 Lexus RX
350 FWD
68,020 mi
$33,599
CarGurus Analysis: 2021 Lexus RX
overall

Summary
With 1,498 currently listed for sale and an average price of $35,381, 36.2% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
74.2% of 2021 RX models on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX continues to stand out as a midsize luxury SUV that makes a strong case for itself with a comfortable cabin, plenty of creature comforts, and Lexus’ long-running reputation for reliability. Its body and mechanics are mostly unchanged for the 2021 model year, which helps reinforce the RX’s familiar formula rather than reinventing it. For buyers who value a relaxed, upscale driving experience, it remains an appealing choice.
What makes the 2021 Lexus RX especially attractive is its balance of comfort and value. The ride quality is a clear strength, and the SUV is described as comfortable and excellent value for money. It also brings a few tech upgrades for 2021, including new standard safety systems. The tradeoffs are worth noting, though: performance is fairly pedestrian, and the technology can be unintuitive.
Other model years to consider
- Average price: $45,746
- Good/great deal percentage: 35.9%
- User rating: 5 / 5
- Total listings: 2,931
- Average price: $49,201
- Good/great deal percentage: 36.5%
- User rating: 5 / 5
- Total listings: 2,929
- Average price: $32,951
- Good/great deal percentage: 36.3%
- User rating: 4.88 / 5
- Total listings: 1,380
This analysis is based on CarGurus' proprietary market data from September 28, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury FWD | $54,050 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport Handling AWD | $52,500 |
| 350 F Sport AWD | $50,100 |
| 350 AWD | $46,620 |
| 350 FWD | $45,220 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
See more price trends2021 Lexus RX Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Chicago: The city of Chicago, IL ($37,510) has the highest average price, likely reflecting a combination of demand and limited inventory.
- Lowest Prices in Miami: Miami, FL ($32,261) offers the lowest average price, indicating a more price-sensitive market or higher inventory turnover.
- Inventory Variation: Cities like Atlanta (164 listings) and New York (164 listings) show strong inventory levels, which may help stabilize prices around the national average.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Chicago, IL | 108 | $37,510 |
| New York, NY | 164 | $34,617 |
| Los Angeles, CA | 129 | $33,968 |
| Dallas, TX | 132 | $33,935 |
| Houston, TX | 147 | $34,307 |
| Philadelphia, PA | 115 | $33,407 |
| Washington, DC | 142 | $34,673 |
| Atlanta, GA | 164 | $35,060 |
| Boston, MA | 104 | $34,956 |
| Miami, FL | 102 | $32,261 |
Pricing by Trim Packages
Key Insights
- FWD vs. AWD Demand: The 350 FWD trim leads in inventory with 2,321 listings, indicating a strong preference for front-wheel drive in the market.
- Premium Pricing for AWD Trims: The 350L Luxury FWD ($54,050 MSRP) is the highest priced trim, reflecting the added features and luxury appeal.
- Competitive Pricing Across Trims: The 350 AWD trim, with 2,008 listings, offers a balance of features and pricing, making it a popular choice among buyers.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 350 FWD | 2,321 | $45,220 | FWD | 3.5L 295 hp V6 |
| 350 AWD | 2,008 | $46,620 | AWD | 3.5L 295 hp V6 |
| 350 F Sport AWD | 416 | $50,100 | AWD | 3.5L 295 hp V6 |
| 350 F Sport Handling AWD | 406 | $52,500 | AWD | 3.5L 295 hp V6 |
| 350L AWD | 155 | $49,450 | AWD | 3.5L 290 hp V6 |
| 350L FWD | 130 | $48,050 | FWD | 3.5L 290 hp V6 |
| 350 F Sport FWD | 98 | $48,700 | FWD | 3.5L 295 hp V6 |
| 350L Luxury FWD | 21 | $54,050 | FWD | 3.5L 290 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models Command Premium: The 2026 Lexus RX is priced at $61,620, reflecting a 20.4% increase over its original MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2014 Lexus RX shows the steepest depreciation at -60.5%, highlighting the rapid value loss typical of older vehicles.
- Best Value in Recent Models: The 2022 Lexus RX is priced at $38,777, representing a -15.0% depreciation, making it a compelling option for buyers seeking a balance of price and modern features.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $51,225 | $61,620 | +20.4% |
| 2025 | $48,975 | $53,487 | +9.3% |
| 2024 | $48,600 | $49,037 | +0.9% |
| 2023 | $47,800 | $45,546 | -4.7% |
| 2022 | $45,920 | $38,777 | -15.0% |
| 2020 | $44,150 | $33,264 | -24.7% |
| 2019 | $43,820 | $29,094 | -33.7% |
| 2018 | $43,470 | $27,288 | -37.2% |
| 2017 | $43,220 | $24,462 | -43.2% |
| 2016 | $41,900 | $22,313 | -46.9% |
| 2015 | $40,970 | $17,701 | -56.8% |
| 2014 | $39,760 | $15,737 | -60.5% |
These recommendations are based on CarGurus' proprietary market data from September 23, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus RX cost?
| Metric | Value |
|---|---|
| Current Average Price | $35,429 |
| Year-Round Low | $35,277 |
| Year-Round High | $36,732 |
| Average Price a Year Ago | $36,510 |
| Change vs. Last Year | −2.96% |
Prices have softened 2.96% compared to this time last year, making it a favorable time to shop this model year.
There are 1,485 listings available, which gives you a solid pool of options to compare.
Is the 2021 Lexus RX a good car?
Yes — the 2021 Lexus RX earns a 4.92/5 user rating, and its expert rating is 7.83/10. The standout strength is Cost effectiveness at 9/10.
Owners consistently praise its reliability, luxurious features, and smooth driving experience. Comfort and handling also come through as recurring positives, which fits the RX’s relaxed, upscale mission. The main trade-offs are that some owners want more storage space and better brake response, while the expert review also notes fairly pedestrian performance and unintuitive technology.
For you, that means the RX makes the most sense if you want a comfortable, well-equipped luxury SUV rather than a sporty one. It’s especially appealing if you value a calm daily driver with a strong reputation for long-term satisfaction.
36.5% of listings are priced as good or great deals, which suggests there are still worthwhile opportunities in the market.
Is the 2021 Lexus RX reliable?
Owners rate it 4.92/5, a strong signal of long-term satisfaction.
The owner feedback repeatedly points to reliability, and it also describes the RX as dependable and smooth to live with over time. The expert review reinforces that theme by noting Lexus’ tradition of reliability and describing the RX as a comfortable cruiser that feels easy to guide in everyday driving.
The cost-effectiveness review also highlights the RX’s value positioning, which matters if you plan to keep the vehicle for years. For used buyers, the main long-term ownership risk is less about durability and more about whether the technology and driving feel still match your expectations.
What should I look for when buying a used 2021 Lexus RX?
At 74.3% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a careful inspection of body panels, paint consistency, and signs of prior repair. Because the RX is often bought for comfort and family use, it also makes sense to check interior wear, seat condition, and how well the electronics and infotainment functions operate. If you’re comparing multiple listings, focus on maintenance records and overall condition rather than mileage alone.
Key things to evaluate:
- Trim level: The base RX comes with standard 18-inch aluminum wheels, LED lighting, rear privacy glass, integrated turn-signal mirrors, NuLuxe-trimmed seats, power-adjustable front seats, a reclining second row, and a power tilt/telescoping steering wheel. The F Sport adds a more aggressive appearance with unique fascia, F Sport badging, F Sport wheels, and performance-oriented trim details, while the extended-body RXL variants add a third row.
- Powertrain: The standard RX uses a 3.5-liter V6 with 295 horsepower and 267 pound-feet of torque paired with an eight-speed automatic transmission. Hybrid versions use a 3.5-liter V6 with three electric motors and an e-CVT, and they come standard with AWD.
- Safety package: Lexus Safety System+ 2.0 is standard and includes pre-collision warning with automatic emergency braking, pedestrian detection, cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. Every RX also includes a rearview camera, 10 airbags, enhanced vehicle stability control, and blind-spot monitoring with rear cross-traffic alert.
- Infotainment: Standard tech includes an 8-inch infotainment touchscreen, voice recognition, Bluetooth, Apple CarPlay, Android Auto, Amazon Alexa, satellite radio, HD Radio, a WiFi hot spot, six USB ports, and a nine-speaker sound system. A 12.3-inch screen is available, but wireless Apple CarPlay and Android Auto are not offered.
- Fuel efficiency: The front-wheel-drive RX 350 returns 20 mpg city, 27 mpg highway, and 23 mpg combined. AWD and RXL versions reduce combined efficiency by 1 mpg, while the RXL with AWD gets 21 mpg combined. Hybrid models return 29 or 31 mpg city and 28 mpg highway, depending on configuration.
Which 2021 Lexus RX trim should I buy?
The 2021 Lexus RX is offered in 5 trim levels: RX, RX F Sport, RXL, RX Hybrid, and RXL Hybrid.
Here's the short version:
- RX: This is the best-value starting point if you want the core RX experience: comfort, strong standard equipment, and the familiar luxury-SUV formula without paying for extra styling or size.
- RX F Sport: Choose this if you want the most driver-focused version, since it adds a sportier look and available handling upgrades, but it’s still more about feel than outright performance.
- RXL: Pick this if you need the extended body and third row, since it adds practicality for families who want more seating flexibility.
- RX Hybrid: This is the efficiency-minded choice, pairing the RX’s comfort with stronger fuel economy and standard AWD.
- RXL Hybrid: Go here if you want the third row and the hybrid powertrain together, though it’s the most specialized option in the lineup.
Lexus Safety System+ 2.0 is standard across the lineup, so you get the same core driver-assistance coverage regardless of trim.
Is now a good time to buy a used 2021 Lexus RX?
This is a moderate market for selective buyers, with enough inventory to shop carefully and enough deal activity to find value.
- Deal availability: 36.5% of listings are priced as good or great deals.
- Inventory: There are 1,485 listings available.
- Price trend: Prices have softened 2.96% compared with last year.
- Clean inventory: 74.3% of listings are accident-free.
If you find a listing below $35,277, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus RX's resale value?
The current average of $35,429 sits slightly below last year's $36,510.
That softer pricing suggests the RX is in a buyer-friendly phase right now, which can help you negotiate if you’re shopping today. For a future seller, it also means resale value may depend more on condition, mileage, and equipment than on market momentum alone. Well-kept examples with strong service history should stand out more clearly when it’s time to sell.
Vehicles with strong owner satisfaction ratings, like this model year's 4.92/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus RX safe?
The 2021 Lexus RX earns a Top Safety Pick designation from IIHS and four-star ratings overall from NHTSA, with five-star side-impact crashworthiness.
It earns an 8/10 safety score from our experts.
Every RX comes with Lexus Safety System+ 2.0, which includes pre-collision warning with automatic emergency braking, pedestrian detection, cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. It also includes a rearview camera, 10 airbags, enhanced vehicle stability control, and blind-spot monitoring with rear cross-traffic alert.
One caveat is that the longer RXL and RXL Hybrid versions were not tested by IIHS, so their crashworthiness is less directly verified than the standard RX.
Should I buy a 2021 Lexus RX or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 36.5% of listings are priced as good or great deals.
- At 74.3% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices have softened 2.96% compared with last year.
- Owners rate it 4.92/5 — a strong satisfaction signal.
- It adds new standard safety systems while keeping the RX’s familiar comfort-focused formula.
Consider the 2020 if:
- At $33,162, the 2020 costs less than the current year's $35,429 average.
- It offers comfort, refinement, and a two-row or three-row layout.
Consider the 2022 if:
- At $39,160, the 2022 costs more than the current year's $35,429 average.
- It brings minimal changes, including new colors and a standalone fog lamps option.
The bottom line: If you want the best balance of price, comfort, and standard safety, the 2021 is the sweet spot. If you’re especially price-sensitive, the 2020 can save you money while keeping much of the same core appeal. If you want a newer model-year example and don’t mind paying more, the 2022 is a reasonable step up, but it doesn’t change the formula much.
These recommendations are based on CarGurus' proprietary market data from September 22, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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