Used 2021 Lexus RX Hybrid for Sale nearTupelo, MS
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 49,253
- Stock #:
- G50116
- VIN:
- 2T2HGMDAXMC067902


Sponsored by Jones GMC
2021 Lexus RX Hybrid
450h AWD
49,253 mi
$41,597
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Blue
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 111,602
- Stock #:
- 70242119
- VIN:
- 2T2SGMDA8MC063272

2021 Lexus RX Hybrid
450h F Sport AWD
111,602 mi
$33,997
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 82,135
- Stock #:
- 70238085
- VIN:
- 2T2YGMDA7LC049646

2020 Lexus RX Hybrid
450h F Sport Performance AWD
82,135 mi
$36,697
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 49,253
- Stock #:
- G50116
- VIN:
- 2T2HGMDAXMC067902

2021 Lexus RX Hybrid
450h AWD
49,253 mi
$41,597
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 21,030
- Stock #:
- RJR3387
- VIN:
- 2T2HGMDA3NC085756

2022 Lexus RX Hybrid
450h AWD
21,030 mi
$42,182
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 21,930
- Stock #:
- 052495
- VIN:
- 2T2YGMDA5LC052495

2020 Lexus RX Hybrid
450h F Sport Performance AWD
21,930 mi
$44,891
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 51,552
- Stock #:
- 080563
- VIN:
- 2T2YGMDA0NC080563

2022 Lexus RX Hybrid
450h F Sport Handling AWD
51,552 mi
$42,933
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 42,000
- Stock #:
- N2027940
- VIN:
- JTJJGKFAXN2027940
Photos coming soon
2022 Lexus RX Hybrid
450hL Luxury AWD
42,000 mi
$48,068
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 69,023
- Stock #:
- 26387
- VIN:
- 2T2HGMDA1MC069134

2021 Lexus RX Hybrid
450h AWD
69,023 mi
$39,089
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 85,643
- Stock #:
- 27966516
- VIN:
- 2T2YGMDA4LC049636

2020 Lexus RX Hybrid
450h F Sport Performance AWD
85,643 mi
$35,247
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch w/Matte Walnut Trim
- Transmission:
- Automatic
- Mileage:
- 46,056
- Stock #:
- 12442TIS-LA
- VIN:
- 2T2HGMDA5NC080431

2022 Lexus RX Hybrid
450h AWD
46,056 mi
$44,088
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 39,672
- Stock #:
- 051326
- VIN:
- 2T2HGMDAXLC051326

2020 Lexus RX Hybrid
450h AWD
39,672 mi
$41,933
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 60,558
- Stock #:
- ND4016
- VIN:
- 2T2HGMDA5MC063417

2021 Lexus RX Hybrid
450h AWD
60,558 mi
$41,307
CarGurus Analysis:
2021 Lexus RX Hybrid
With 237 currently listed for sale and an average price of $39,381, 34.6% of 2021 Lexus RX Hybrid listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX Hybrid 4.67 / 5 stars.
79.3% of 2021 Lexus RX Hybrid listings on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 9,499
- Stock #:
- 70194048
- VIN:
- 2T2HGMDA9NC090556

2022 Lexus RX Hybrid
450h AWD
9,499 mi
$51,497
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 54,986
- Stock #:
- 29095825
- VIN:
- 2T2YGMDA4NC075978

2022 Lexus RX Hybrid
450h F Sport Handling AWD
54,986 mi
$45,197
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 41,511
- Stock #:
- 70218475
- VIN:
- 2T2JGMDA9MC069318

2021 Lexus RX Hybrid
450h AWD
41,511 mi
$44,197
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- CHAMPAGNE
- Transmission:
- Automatic
- Mileage:
- 33,605
- Stock #:
- 70026835
- VIN:
- 2T2HGMDA7MC069851

2021 Lexus RX Hybrid
450h AWD
33,605 mi
$42,247
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 81,929
- Stock #:
- L26084G
- VIN:
- 2T2AGMDA0LC054463

2020 Lexus RX Hybrid
450h AWD
81,929 mi
$36,186
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 34,013
- Stock #:
- 28957392
- VIN:
- JTJJGKFA0L2014823

2020 Lexus RX Hybrid
450hL Luxury AWD
34,013 mi
$47,197
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 42,524
- Stock #:
- 28763516
- VIN:
- JTJJGKFA9N2022793

-$1,000
2022 Lexus RX Hybrid
450hL Luxury AWD
42,524 mi
$49,147
$48,147
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (Beige)
- Transmission:
- Automatic
- Mileage:
- 61,752
- Stock #:
- 081790
- VIN:
- 2T2HGMDA5NC081790

2022 Lexus RX Hybrid
450h AWD
61,752 mi
$42,045
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 40,579
- Stock #:
- 70230634
- VIN:
- JTJHGKFA7N2028266

2022 Lexus RX Hybrid
450hL AWD
40,579 mi
$48,397
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Palamino
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 119,047
- Stock #:
- 29025
- VIN:
- 2T2JGMDA7MC062562

2021 Lexus RX Hybrid
450hL Luxury AWD
119,047 mi
$32,232
CarGurus Analysis: 2021 Lexus RX Hybrid

Summary
With 237 currently listed for sale and an average price of $39,381, 34.6% of 2021 Lexus RX Hybrid listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX Hybrid 4.67 / 5 stars.
79.3% of 2021 Lexus RX Hybrid listings on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX Hybrid stands out as a luxury crossover that blends comfort, efficiency, and a strong reputation for reliability. Lexus has long been associated with hybrid technology in the premium segment, and the RX Hybrid’s appeal is rooted in that combination of fuel-saving engineering and a refined driving experience. Owners also tend to praise its smooth and powerful performance, luxurious features, and comfortable ride, which fit the RX’s upscale character well.
For this generation, the RX Hybrid lineup offered a range of powertrains and trims, including the RX 350h, RX 500h, and RX 450h+ Plug-In Hybrid. The RX 350h came standard with all-wheel drive, a 9.8-inch touchscreen with wireless Apple CarPlay and Android Auto, three-zone automatic climate control, heated and power-operated front seats, and faux leather upholstery. Higher trims added features such as a sunroof, roof rails, ventilated front seats with memory positioning, a wireless smartphone charger, upgraded interior lighting, a larger 14-inch infotainment system, and a head-up display. The RX 500h brought more performance, along with standard four-wheel steering, while the RX 450h+ added plug-in capability and an electric-only driving range of up to 37 miles per charge.
The main tradeoff is that the RX Hybrid can be expensive on the used market, and it is not as fast or fun to drive as some rivals. Even so, it remains appealing for buyers who want a premium hybrid SUV with a quiet, comfortable ride, strong efficiency, and a well-finished interior.
Other model years to consider
- 2024 Lexus RX Hybrid
- Average price: $56,035
- Good/great deal percentage: 37.3%
- User rating: 5 / 5
- Total listings: 722
- 2018 Lexus RX Hybrid
- Average price: $28,186
- Good/great deal percentage: 44.8%
- User rating: 5 / 5
- Total listings: 174
- 2017 Lexus RX Hybrid
- Average price: $26,096
- Good/great deal percentage: 42.8%
- User rating: 5 / 5
- Total listings: 138
Similar models to consider
- 2021 Toyota RAV4 Hybrid
- Average price: $28,477
- Good/great deal percentage: 36.2%
- User rating: 4.82 / 5
- Total listings: 2,268
- 2021 Honda CR-V Hybrid
- Average price: $26,035
- Good/great deal percentage: 35.8%
- User rating: 4.89 / 5
- Total listings: 737
- 2021 Ford Escape Hybrid
- Average price: $18,091
- Good/great deal percentage: 33.9%
- User rating: 4 / 5
- Total listings: 566
This analysis is based on CarGurus' proprietary market data from October 12, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
David D
Reviewed a 2021 Lexus 450h AWD on Aug 25, 2025
I think it’s the most enjoyable car I’ve ever driven in my 66 years of driving
Anonymous
Reviewed a 2021 Lexus RX Hybrid on Mar 11, 2021
Smooth, comfortable, reliable, full of amenities, beautiful! Puts a smile on my face every morning!
Antonio B
Reviewed a 2021 Lexus RX Hybrid on Jun 9, 2021
Overall The RX 450 h is very powerful ,smooth driving, excellent control, Very stylish and offers you the luxury of the Lexus brand.
B M
Reviewed a 2021 Lexus 450h F Sport Handling AWD on Mar 10, 2024
Great mileage with pretty good size SUV. 3 years of use and close to 100,000 miles with no issues whatsoever . This is a keeper
2021 Lexus RX Hybrid Trims
| Trim type | MSRP |
|---|---|
| 450hL AWD | $51,310 |
| 450h F Sport Handling AWD | $53,720 |
| 450hL Luxury AWD | $57,310 |
| 450h F Sport AWD | $51,400 |
| 450h AWD | $47,920 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus RX Hybrid Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX Hybrid prices has changed over time.
See more price trends2021 Lexus RX Hybrid Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest-Price Market: Atlanta, GA leads with an average price of $45,749, indicating a premium demand in this region.
- Best Value: New York, NY offers the lowest average price at $35,675, suggesting a more competitive market for buyers.
- Inventory Drives Stability: Los Angeles, CA has the most listings at 46, which may contribute to more stable pricing dynamics in that market.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Los Angeles, CA | 46 | $38,152 |
| Philadelphia, PA | 32 | $39,992 |
| New York, NY | 31 | $35,675 |
| Atlanta, GA | 29 | $45,749 |
| Boston, MA | 29 | $37,034 |
| Dallas, TX | 28 | $35,751 |
| Washington, DC | 27 | $40,166 |
| Chicago, IL | 22 | $40,495 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 450h AWD trim has the highest inventory with 443 listings, indicating strong consumer interest.
- Premium Spread: The 450hL Luxury AWD trim, priced at $57,310, represents the highest MSRP, reflecting a premium offering in the lineup.
- Drivetrain Effect: All trims feature an AWD drivetrain, which may enhance their appeal in markets with varying weather conditions.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450h AWD | 443 | $47,920 | AWD | 3.5L 308 hp V6 Hybrid |
| 450h F Sport AWD | 73 | $51,400 | AWD | 3.5L 308 hp V6 Hybrid |
| 450hL AWD | 45 | $51,310 | AWD | 3.5L 308 hp V6 Hybrid |
| 450hL Luxury AWD | 30 | $57,310 | AWD | 3.5L 308 hp V6 Hybrid |
| 450h F Sport Handling AWD | 8 | $53,720 | AWD | 3.5L 308 hp V6 Hybrid |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2026 model year shows a significant average price of $70,673, reflecting a 32.0% premium over its starting MSRP.
- Depreciation Curve: The 2015 model year exhibits the steepest depreciation at -61.9%, indicating a rapid decline in value for older models.
- Best Value Sweet Spot: The 2022 model year is priced below its starting MSRP at $42,718, suggesting it may offer the best value for budget-conscious buyers.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2026 | $53,525 | $70,673 | +32.0% |
| 2025 | $51,125 | $60,145 | +17.6% |
| 2024 | $50,750 | $55,828 | +10.0% |
| 2023 | $49,400 | $50,915 | +3.1% |
| 2022 | $48,720 | $42,718 | -12.3% |
| 2021 | $47,920 | $39,123 | -18.4% |
| 2020 | $46,800 | $35,753 | -23.6% |
| 2019 | $46,245 | $31,896 | -31.0% |
| 2018 | $45,895 | $29,128 | -36.5% |
| 2017 | $53,035 | $26,864 | -49.3% |
| 2016 | $52,235 | $24,069 | -53.9% |
| 2015 | $47,620 | $18,146 | -61.9% |
These recommendations are based on CarGurus' proprietary market data from October 7, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus RX Hybrid cost?
| Metric | Value |
|---|---|
| Current Average Price | $39,352 |
| Year-Round Low | $38,493 |
| Year-Round High | $40,587 |
| Average Price a Year Ago | $39,862 |
| Change vs. Last Year | −1.28% |
Prices have softened 1.28% compared to this time last year, making it a favorable time to shop this model year.
There are 240 listings available, which gives you a modest amount of inventory to compare before you buy.
Is the 2021 Lexus RX Hybrid a good car?
Yes — 4.67/5 is a strong user rating, and it lines up with the model’s appeal as a comfortable, efficient luxury crossover. Owners consistently praise the smooth and powerful performance, luxurious features, and overall reliability. The RX Hybrid also fits well if you want a premium SUV with a quiet ride and a refined interior. With 35.0% of listings marked as good or great deals, you have some room to shop selectively.
Is the 2021 Lexus RX Hybrid reliable?
Owners rate it 4.67/5, a strong signal of long-term satisfaction.
The review summary points to reliability, dependability, and a trouble-free ownership experience as major strengths, along with the kind of long-term confidence buyers often want in a hybrid SUV. That matters if you plan to keep the vehicle for years, because strong owner confidence usually suggests fewer surprises over time. For used buyers, the main long-term risk is paying too much for a premium hybrid that still needs careful condition checks before purchase.
What should I look for when buying a used 2021 Lexus RX Hybrid?
Accident-free inventory is solid at 79.6% — always verify the vehicle history report.
You should start with a history report to confirm accident status, title history, and service records. After that, prioritize a thorough inspection of the hybrid system, brakes, tires, and interior electronics, since premium features can be costly to sort out later. Focus on overall condition and maintenance consistency, especially if you’re comparing higher-priced listings.
Is now a good time to buy a used 2021 Lexus RX Hybrid?
This is a moderate market, so you can shop selectively without expecting a deep buyer’s market.
- Deal availability: 35.0% of listings are priced as good or great deals.
- Inventory: There are 240 listings available.
- Price trend: Prices have softened 1.28% compared with last year.
- Clean inventory: 79.6% of listings are accident-free.
If you find a listing below $38,493, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus RX Hybrid's resale value?
The current average of $39,352 sits slightly below last year's $39,862.
That tells you the market has eased a bit, which can help you buy more carefully now but may also mean future resale gains are limited if prices stay soft. For a seller, the current trend suggests you should expect a competitive market rather than a rising one. Well-kept examples with strong equipment and clean history should still draw interest, especially because buyers tend to value this model’s comfort and reliability.
Vehicles with strong owner satisfaction ratings, like this model year's 4.67/5, tend to retain buyer demand, which supports resale value over time.
Should I buy a 2021 Lexus RX Hybrid or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 35.0% of listings are priced as good or great deals.
- Accident-free inventory is solid at 79.6% — always verify the vehicle history report.
- Price trend: Prices have softened 1.28% compared with last year.
- Owners rate it 4.67/5 — a strong satisfaction signal.
The bottom line:
The 2021 is a strong choice if you want a well-liked, comfortable, and efficient luxury hybrid SUV at a price that has eased a bit from last year. If you’re focused on value, the 2021 makes sense as long as you find a clean, well-maintained example. If you’re more price-sensitive, you may want to compare nearby years and target the best-maintained listing rather than the newest one.
These recommendations are based on CarGurus' proprietary market data from October 13, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
Relevant articles

The Best Hybrid SUVs of 2026
Hybrid SUVs combine great fuel economy with big trunks and plenty of capability. These are our top 10 picks.

Best Lexus Deals in October 2026
Leasing a Lexus can be a great way to get into a new car from one of the most popular luxury brands at a more affordable monthly rate. Here are the best deals we've found this month on Lexus vehicles.

The Top Used SUVs With the Best Gas Mileage in 2026
If you want a spacious vehicle that delivers good gas mileage, and if you're shopping on a budget, then this list of the top used SUVs with the best gas mileage is for you.