2021 Nissan Murano vs 2022 Honda Odyssey
Overview | |
MSRP$32,810 | MSRP$33,040 |
Listings548 | Listings526 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews7.8 out of 10 | Expert reviews7.0 out of 10 |
Pros
Cons
| Pros
Cons
|
2021 Nissan Murano Reviews SummaryWhile most midsize SUVs offer three rows, the 2021 Nissan Murano focuses on two rows of comfortable seating. Rivals like the Honda Passport have come on the scene in recent years, but Nissan’s comfortable crossover never left. The Murano was introduced in 2002 as a 2003 model, and the third generation arrived for the 2015 model year. Last refreshed for 2019, the Murano carries over into the 2021 model year largely unchanged, although it does get some additional standard safety features. | |
2022 Honda Odyssey Reviews SummaryIf you are a minivan aficionado like we are, then you know that the 2022 Honda Odyssey is the most enjoyable one to drive. It has that light, effortless, responsive driving character that Honda bakes into every one of its cars, trucks, SUVs, and minivans. But you also know that the Odyssey’s rivals are successfully outflanking it in terms of stylish design, all-weather capability, electrified efficiency, infotainment technology, and outright luxury. In response to these new threats, Honda makes no changes to the 2022 Odyssey. Good thing its “original recipe” approach remains pretty tasty. | |
No video found | No video found |
Popular Features & Specs | |
Engine3.5L 260 hp V6 | Engine3.5L 280 hp V6 |
Drive TrainFWD | Drive TrainFWD |
Seating Capacity5 | Seating Capacity7 |
Horsepower260 hp @ 6000 rpm | Horsepower280 hp @ 6000 rpm |
MPG City20 | MPG City19 |
MPG Highway28 | MPG Highway28 |
Engine | |
Engine Name3.5L 260 hp V6 | Engine Name3.5L 280 hp V6 |
Torque240 lb-ft @ 4400 rpm | Torque262 lb-ft @ 4700 rpm |
Horsepower260 hp @ 6000 rpm | Horsepower280 hp @ 6000 rpm |
DrivetrainFWD | DrivetrainFWD |
Fuel Economy | |
MPG City20 | MPG City19 |
MPG Highway28 | MPG Highway28 |
Interior | |
Seating Capacity5 | Seating Capacity7 |
Safety | |
Front Crash Overall5 | Front Crash Overall5 |
Side Crash Overall5 | Side Crash Overall5 |
Dimensions & Capacity | |
Cargo Space32.1 cu ft | Cargo Space32.8 cu ft |
Curb Weight3833 lbs | Curb Weight4398 lbs |
Height67.8 in | Height68.3 in |
Length192.8 in | Length205.2 in |
Width75.4 in | Width78.5 in |
Wheelbase111.2 in | Wheelbase118.1 in |
Maximum Payload1277 lbs | Maximum Payload1621 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity | Maximum Towing Capacity3500 lbs |
Overview | ||
MSRP | $32,810 | $33,040 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 7.8 out of 10Read full review | 7.0 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | While most midsize SUVs offer three rows, the 2021 Nissan Murano focuses on two rows of comfortable seating. Rivals like the Honda Passport have come on the scene in recent years, but Nissan’s comfortable crossover never left. The Murano was introduced in 2002 as a 2003 model, and the third generation arrived for the 2015 model year. Last refreshed for 2019, the Murano carries over into the 2021 model year largely unchanged, although it does get some additional standard safety features. | If you are a minivan aficionado like we are, then you know that the 2022 Honda Odyssey is the most enjoyable one to drive. It has that light, effortless, responsive driving character that Honda bakes into every one of its cars, trucks, SUVs, and minivans. But you also know that the Odyssey’s rivals are successfully outflanking it in terms of stylish design, all-weather capability, electrified efficiency, infotainment technology, and outright luxury. In response to these new threats, Honda makes no changes to the 2022 Odyssey. Good thing its “original recipe” approach remains pretty tasty. |
Video | No video found | No video found |
Popular Features & Specs | ||
Engine | 3.5L 260 hp V6 | 3.5L 280 hp V6 |
Drive Train | FWD | FWD |
Seating Capacity | 5 | 7 |
Horsepower | 260 hp @ 6000 rpm | 280 hp @ 6000 rpm |
MPG City | 20 | 19 |
MPG Highway | 28 | 28 |
Engine | ||
Engine Name | 3.5L 260 hp V6 | 3.5L 280 hp V6 |
Torque | 240 lb-ft @ 4400 rpm | 262 lb-ft @ 4700 rpm |
Horsepower | 260 hp @ 6000 rpm | 280 hp @ 6000 rpm |
Drivetrain | FWD | FWD |
Fuel Economy | ||
MPG City | 20 | 19 |
MPG Highway | 28 | 28 |
Interior | ||
Seating Capacity | 5 | 7 |
Safety | ||
Front Crash Overall | 5 | 5 |
Side Crash Overall | 5 | 5 |
Dimensions & Capacity | ||
Cargo Space | 32.1 cu ft | 32.8 cu ft |
Curb Weight | 3833 lbs | 4398 lbs |
Height | 67.8 in | 68.3 in |
Length | 192.8 in | 205.2 in |
Width | 75.4 in | 78.5 in |
Wheelbase | 111.2 in | 118.1 in |
Maximum Payload | 1277 lbs | 1621 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 3500 lbs | |
The 2021 Nissan Murano, once a pioneer in design, had settled into a more conventional aesthetic by 2021. Its L-shaped LED headlights and contoured front end were no longer groundbreaking but remained stylish. Inside, the Murano maintained a conservative yet functional design, prioritizing comfort and ease of use. The cabin's restrained styling ensured that controls were intuitive and accessible, making it an ideal choice for those seeking a comfortable SUV for daily commutes and long road trips. The Murano offered four trims: S, SV, SL, and Platinum, each adding progressively more features, from basic amenities like dual-zone climate control and an 8-inch touchscreen to luxury touches like a panoramic moonroof and premium leather in the Platinum trim.
In contrast, the 2022 Honda Odyssey was a minivan designed with family convenience in mind. Its sliding side doors and spacious interior made it a practical choice for families, offering easy access to rear seats and ample cargo space. The Odyssey's design, while adhering to traditional minivan aesthetics, included stylish elements like kinked sliding doors and dark gray aluminum wheels on the Elite trim. The interior was thoughtfully designed with quality materials and numerous storage solutions. The Odyssey's Magic Slide second-row seats and comfortable third-row seating provided flexibility and comfort for passengers. The Elite trim featured premium amenities like leather upholstery, a tri-zone climate control system, and an onboard vacuum cleaner.














The 2021 Nissan Murano was powered by a 3.5-liter V6 engine producing 260 horsepower and 240 pound-feet of torque. This engine, paired with a continuously variable transmission (CVT), offered standard front-wheel drive with an option for all-wheel drive. The Murano excelled in low-speed acceleration, making it ideal for city driving, though the CVT could dampen power at higher speeds. Its comfort-first ride absorbed road imperfections well, making it a suitable choice for long journeys. However, its towing capacity was limited to 1,500 pounds, which was lower than many midsize and even some compact SUVs.
The 2022 Honda Odyssey featured a 3.5-liter V6 engine delivering 280 horsepower and 262 pound-feet of torque, paired with a 10-speed automatic transmission. Unlike some competitors, the Odyssey did not offer all-wheel drive or a hybrid powertrain, resulting in an EPA fuel economy estimate of 22 mpg combined. Despite this, the Odyssey was enjoyable to drive, with responsive handling and quick acceleration. However, its brakes could become overworked on long descents, leading to pedal vibration. Overall, the Odyssey provided a pleasant driving experience, balancing performance with practicality for family use.
The 2021 Nissan Murano offered up to 67 cubic feet of cargo space with the rear seats folded and 32.1 cubic feet with them in use. While this was less than some competitors, the Murano compensated with user-friendly features like a hands-free power liftgate on higher trims. Its focus on two rows of seating provided ample headroom and legroom, ensuring comfort for all passengers.
The 2022 Honda Odyssey excelled in interior space and versatility. With wide-opening doors and a low step-in height, access was easy. The Odyssey offered 32.8 cubic feet of cargo space behind the third row, expanding to 88.8 cubic feet with the third row folded. Removing the second-row seats provided a massive 144.9 cubic feet of cargo space. The Magic Slide second-row seats added flexibility, allowing for various seating configurations. The Odyssey's interior was designed for family convenience, with numerous storage solutions and comfortable seating for all passengers.
The 2021 Nissan Murano came standard with an 8-inch touchscreen infotainment system, featuring Apple CarPlay and Android Auto. The system's intuitive layout and physical controls made it user-friendly. Higher trims offered an 11-speaker Bose premium stereo and navigation.
The 2022 Honda Odyssey Elite was equipped with a range of technology features, though its infotainment system lagged behind competitors. Starting with the EX trim, the Odyssey included an 8-inch touchscreen, satellite radio, and smartphone integration. Touring and Elite trims added navigation, CabinWatch, and CabinTalk technologies. The rear-seat entertainment system, standard on Touring and Elite trims, included a 10.2-inch display and wireless headphones. However, the system felt outdated compared to rivals. The Elite trim also featured an 11-speaker audio system and wireless charging.
The 2021 Nissan Murano was equipped with Nissan Safety Shield 360, offering features like reverse automatic emergency braking, blind-spot monitoring, and lane departure warning. Additional safety features were available on higher trims.
The 2022 Honda Odyssey came standard with Honda Sensing, which included adaptive cruise control, forward-collision warning, and lane-keeping assist. However, the system lacked refinement, occasionally issuing false warnings. The Odyssey received a five-star rating from the NHTSA and a Top Safety Pick+ from the IIHS, highlighting its strong safety credentials.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Nissan Murano was 7.8 out of 10, while the 2022 Honda Odyssey scored 7.0 out of 10. Based on these ratings, the 2021 Nissan Murano is the recommended choice, offering a better balance of comfort, technology, and performance for most consumers.
Choose the 2021 Nissan Murano if:
- You prioritize a comfortable and stylish SUV for commuting and road trips.
- You prefer a user-friendly infotainment system with physical controls.
- You value a conservative yet functional interior design.
Choose the 2022 Honda Odyssey if:
- You need a spacious and versatile vehicle for family use.
- You appreciate innovative seating solutions like Magic Slide second-row seats.
- You prioritize safety features and strong crash-test ratings.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Nissan Murano was 7.8 out of 10, while the 2022 Honda Odyssey scored 7.0 out of 10. Based on these ratings, the 2021 Nissan Murano is the recommended choice, offering a better balance of comfort, technology, and performance for most consumers.
Choose the 2021 Nissan Murano if:
Shop Now- You prioritize a comfortable and stylish SUV for commuting and road trips.
- You prefer a user-friendly infotainment system with physical controls.
- You value a conservative yet functional interior design.
Choose the 2022 Honda Odyssey if:
Shop Now- You need a spacious and versatile vehicle for family use.
- You appreciate innovative seating solutions like Magic Slide second-row seats.
- You prioritize safety features and strong crash-test ratings.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.








































