2021 Lexus IS vs 2021 Mercedes-Benz E-Class
Overview | |
MSRP$54,250 | MSRP$39,050 |
Listings285 | Listings171 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews8.3 out of 10 | Expert reviews7.3 out of 10 |
Pros
Cons
| Pros
Cons
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2021 Mercedes-Benz E-Class Reviews SummaryWhen money is but a mild concern, a brand-new Mercedes-Benz is a reasonable purchase. The E-Class is the company's most practical and versatile car, as high-quality and necessary in a nice garage as a Kitchen-Aid mixer is in a baker's kitchen. It offers four body styles, four engines, and dozens of color schemes. Fast or efficient? Loud or library quiet? Modest or rich as hell? The E-Class is all of those things, depending on which of the 13 models you order and how deep into the options list you dive. For 2021, the E-Class receives a mid-cycle update for the infotainment system, engines, and exterior styling. We tested the AMG E53 that features a mild-hybrid inline-six powertrain. | |
2021 Lexus IS Reviews SummaryThe Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be. | |
Popular Features & Specs | |
Engine2.0L 255 hp I4 | Engine2.0L 241 hp I4 |
Drive TrainRWD | Drive TrainRWD |
Seating Capacity5 | Seating Capacity5 |
Horsepower255 hp @ 5800 rpm | Horsepower241 hp @ 5800 rpm |
MPG City22 | MPG City21 |
MPG Highway31 | MPG Highway31 |
Engine | |
Engine Name2.0L 255 hp I4 | Engine Name2.0L 241 hp I4 |
Torque273 lb-ft @ 1800 rpm | Torque258 lb-ft @ 1650 rpm |
Horsepower255 hp @ 5800 rpm | Horsepower241 hp @ 5800 rpm |
DrivetrainRWD | DrivetrainRWD |
Fuel Economy | |
MPG City22 | MPG City21 |
MPG Highway31 | MPG Highway31 |
Interior | |
Seating Capacity5 | Seating Capacity5 |
Key Features | |
Navigation SystemStandard | Navigation System |
Sunroof/MoonroofStandard | Sunroof/Moonroof |
Safety | |
Front Crash Overall5 | Front Crash Overall4 |
Side Crash Overall5 | Side Crash Overall5 |
Dimensions & Capacity | |
Cargo Space13.1 cu ft | Cargo Space10.8 cu ft |
Curb Weight3781 lbs | Curb Weight3715 lbs |
Height57.8 in | Height56.5 in |
Length194.3 in | Length185.4 in |
Width81.3 in | Width72.4 in |
Wheelbase115.7 in | Wheelbase110.2 in |
Number of doors4 | Number of doors4 |
Overview | ||
MSRP | $54,250 | $39,050 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 8.3 out of 10Read full review | 7.3 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | When money is but a mild concern, a brand-new Mercedes-Benz is a reasonable purchase. The E-Class is the company's most practical and versatile car, as high-quality and necessary in a nice garage as a Kitchen-Aid mixer is in a baker's kitchen. It offers four body styles, four engines, and dozens of color schemes. Fast or efficient? Loud or library quiet? Modest or rich as hell? The E-Class is all of those things, depending on which of the 13 models you order and how deep into the options list you dive. For 2021, the E-Class receives a mid-cycle update for the infotainment system, engines, and exterior styling. We tested the AMG E53 that features a mild-hybrid inline-six powertrain. | The Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be. |
Video | ||
Popular Features & Specs | ||
Engine | 2.0L 255 hp I4 | 2.0L 241 hp I4 |
Drive Train | RWD | RWD |
Seating Capacity | 5 | 5 |
Horsepower | 255 hp @ 5800 rpm | 241 hp @ 5800 rpm |
MPG City | 22 | 21 |
MPG Highway | 31 | 31 |
Engine | ||
Engine Name | 2.0L 255 hp I4 | 2.0L 241 hp I4 |
Torque | 273 lb-ft @ 1800 rpm | 258 lb-ft @ 1650 rpm |
Horsepower | 255 hp @ 5800 rpm | 241 hp @ 5800 rpm |
Drivetrain | RWD | RWD |
Fuel Economy | ||
MPG City | 22 | 21 |
MPG Highway | 31 | 31 |
Interior | ||
Seating Capacity | 5 | 5 |
Key Features | ||
Navigation System | Standard | |
Sunroof/Moonroof | Standard | |
Safety | ||
Front Crash Overall | 5 | 4 |
Side Crash Overall | 5 | 5 |
Dimensions & Capacity | ||
Cargo Space | 13.1 cu ft | 10.8 cu ft |
Curb Weight | 3781 lbs | 3715 lbs |
Height | 57.8 in | 56.5 in |
Length | 194.3 in | 185.4 in |
Width | 81.3 in | 72.4 in |
Wheelbase | 115.7 in | 110.2 in |
Number of doors | 4 | 4 |
The 2021 Mercedes-Benz E-Class, part of the W213 generation, showcased a design evolution that embraced the "sensual purity" theme, moving away from the sharper angles of its predecessor. This model featured a more fluid and curvier form, reminiscent of the S-Class and C-Class models from earlier years. The E-Class received updates that included squinted headlights and an inverted trapezoid grille, giving it a slightly edgier appearance. Despite these changes, it maintained its reputation as a handsome and elegant vehicle, available in sedan, wagon, coupe, and convertible forms. Inside, the E-Class boasted a luxurious cabin filled with rich materials like polished woods, aluminum, and carbon fiber, creating an inviting and opulent atmosphere. The interior was equipped with advanced technology, including two 12-inch screens and a digital display, making it a modern and lavish space.
In contrast, the 2021 Lexus IS presented a sporty and athletic design, with a stance that conveyed motion even when stationary. Its elegant proportions were highlighted by a fast roofline and a distinctive kick-up of the window base, giving it a compact and sporty look. The IS featured a new version of the Lexus signature "spindle" grille with diamond mesh and narrow headlights, adding to its assertive appearance. The interior of the IS was tastefully simple, with a center stack resembling a retro hi-fi setup. While the analog clock felt outdated, the overall design was bold and modern, matching the exterior's assertive choices. The IS aimed to reflect the driver's personality, offering a balance of elegance and sportiness.
















The 2021 Mercedes-Benz E-Class introduced significant changes to its powertrain lineup, with the E450 model transitioning to a hybrid system featuring a 48-volt electrical system. This setup provided additional power and torque, enhancing fuel efficiency and reducing emissions. The E450's inline-six engine delivered 362 horsepower and 369 lb-ft of torque, with overboost capabilities. The AMG E53 model added a second turbo, resulting in 429 horsepower and 384 lb-ft of torque, offering brisk acceleration and a refined driving experience. The AMG E63 S, with its hand-built 4.0-liter V8 engine, produced an impressive 603 horsepower and 627 lb-ft of torque, making it a high-performance option. Despite its power, the E-Class maintained a comfortable ride, with fuel economy ratings ranging from 18 to 26 mpg combined, depending on the model.
The 2021 Lexus IS offered a range of powertrains, starting with the IS 300 RWD, which featured a 2.0-liter turbocharged inline-four engine producing 241 horsepower and 258 lb-ft of torque. The IS 300 AWD came with a naturally aspirated 3.5-liter V6 engine, delivering 260 horsepower and 236 lb-ft of torque. The IS 350 models, both AWD and RWD, used the same V6 engine but tuned to produce 311 horsepower and 280 lb-ft of torque. The IS provided a balanced and precise driving experience, with a 54/46 front/rear weight distribution and a well-tuned suspension system. Fuel efficiency varied, with the IS 300 RWD achieving 25 mpg combined, while the IS 350 AWD managed 22 mpg combined.
The 2021 Mercedes-Benz E-Class offered a spacious and comfortable cabin, accommodating four adults with ample headroom and legroom. The interior featured supportive cushions and various convenience features, such as separate climate controls and seat adjustments on the doors. The E-Class provided different body styles, including a coupe with usable rear seats and a wagon with a stowable rear-facing jump seat, offering up to 64 cubic feet of cargo space. The sedan's trunk measured 13 cubic feet, while the two-door models had slightly less space. The E-Class All-Terrain wagon added ground clearance and body cladding for a more rugged appearance.
The 2021 Lexus IS focused on driver-centered design, with a comfortable and adjustable driver position. The F Sport trim's bolstered seats, standard in IS 350 models, offered heating and ventilation. The IS featured NuLuxe synthetic upholstery, providing a leather-like feel without the added cost and maintenance. Storage options included an open cubby, twin cupholders, and spacious door pockets. The second row was comfortable for two passengers, though legroom required negotiation with front-seat occupants. The trunk offered 10.8 cubic feet of space, with a deep configuration and a temporary spare tire stored beneath the load floor.
The 2021 Mercedes-Benz E-Class featured the MBUX infotainment system, offering a touchscreen interface with improved organization and shortcut buttons for major functions. Gesture controls and natural voice processing enhanced user interaction, while features like live camera feeds and massaging seats added convenience and luxury. The system lacked over-the-air updates, and Apple CarPlay and Android Auto were not wireless. Optional driving assists provided advanced safety features, and the instrument cluster offered customizable displays with various graphics and colors.
The 2021 Lexus IS introduced a touchscreen infotainment system compatible with Android Auto and Apple CarPlay. The IS included Lexus Enform connected services, offering free trial periods for features like Safety Connect, Service Connect, and WiFi. The Navigation Package, available as an option, included Dynamic Navigation and Destination Assist for three years. The Mark Levinson premium audio system, with 17 speakers and 1,800 watts, provided an exceptional listening experience. The IS's technology offerings aimed to enhance convenience and entertainment for drivers and passengers.
The 2021 Mercedes-Benz E-Class received high safety ratings, with a five-star overall rating from the NHTSA and a "Top Safety Pick+" designation from the IIHS for the sedan. The E-Class featured innovative safety technologies, such as Pre-Safe Sound and side bolster inflation during side collisions. Standard safety features included forward automatic emergency braking, a driver-attention monitor, and blind-spot monitoring, with additional driver-assist features available as options.
The 2021 Lexus IS had not yet been rated by the IIHS or NHTSA, but it was expected to perform well based on its platform. The IS came equipped with the Lexus Safety System+ 2.5, offering a comprehensive suite of safety features, including a pre-collision system with pedestrian detection, lane-departure warning, and adaptive cruise control. Additional safety features included blind-spot monitoring, a backup camera, and LED lighting. The IS aimed to provide a safe and secure driving experience for its occupants.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz E-Class is 8.3 out of 10, while the 2021 Lexus IS scores 7.3 out of 10. Based on these ratings, the 2021 Mercedes-Benz E-Class is the recommended choice, offering a superior combination of luxury, performance, and safety features.
Choose the 2021 Lexus IS if:
- You prefer a sporty and athletic design with a focus on driver-centered features.
- You want a vehicle with a balanced and precise driving experience.
- You appreciate a comprehensive suite of standard safety features and connected services.
Choose the 2021 Mercedes-Benz E-Class if:
- You prioritize a luxurious and spacious interior with advanced technology features.
- You seek a range of powerful engine options, including high-performance AMG models.
- You value a vehicle with top safety ratings and innovative safety technologies.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz E-Class is 8.3 out of 10, while the 2021 Lexus IS scores 7.3 out of 10. Based on these ratings, the 2021 Mercedes-Benz E-Class is the recommended choice, offering a superior combination of luxury, performance, and safety features.
Choose the 2021 Lexus IS if:
Shop Now- You prefer a sporty and athletic design with a focus on driver-centered features.
- You want a vehicle with a balanced and precise driving experience.
- You appreciate a comprehensive suite of standard safety features and connected services.
Choose the 2021 Mercedes-Benz E-Class if:
Shop Now- You prioritize a luxurious and spacious interior with advanced technology features.
- You seek a range of powerful engine options, including high-performance AMG models.
- You value a vehicle with top safety ratings and innovative safety technologies.

By: CarGurus + AI
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