2021 Mercedes-Benz S-Class vs 2021 Lexus IS

2021 Lexus IS
2021 Lexus IS
$39,050MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz S-Class
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now
2021 Lexus IS
$39,050MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP

$39,050

MSRP

$109,800

Listings

171

Listings

196

Ratings & Reviews

User Reviews
User Reviews

Expert reviews

7.3 out of 10

Expert reviews

7.5 out of 10

Pros

  • Stylish design

  • Multiple powertrain options

  • Great handling

Cons

  • Underwhelming base engine

  • Irritating transmission

  • Outdated technology

Pros

  • Powerful engine

  • Comfortable

  • Impressive technology

Cons

  • High price

2021 Lexus IS Reviews Summary

The Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be.

2021 Mercedes-Benz S-Class Reviews Summary

The S-Class not only sits at the top of the Mercedes hierarchy in price and prestige, but it has also long served as a technological showcase. In the press release for the redesigned 2021 S-Class, Mercedes repeatedly noted the innovations—from anti-lock brakes to airbags—that were introduced on the big sedan and eventually trickled down to mainstream vehicles.

With the previous generation dating back to the 2014 model year (with a significant update for 2018), the Mercedes-Benz S-Class was in need of an update to maintain that status, and to keep pace with other full-size luxury sedans like the Audi A8, BMW 7 Series, and Lexus LS. To do that, the new S-Class gets a more sophisticated infotainment system, new powertrains, and more aerodynamic bodywork, among other features.

The 2021 S-Class launches in two configurations, both with 4Matic all-wheel drive (AWD) and EQ Boost mild-hybrid systems. The S500 4Matic has a six-cylinder engine, while the S580 4Matic has a V8. We spent a few days with the Mercedes-Benz S580 for this review. A Mercedes-Maybach S680 4Matic version will follow in the first half of 2022, and you can expect a new AMG performance version sometime in the future as well.

Popular Features & Specs

Engine

2.0L 241 hp I4

Engine

3.0L 429 hp I6

Drive Train

RWD

Drive Train

AWD

Seating Capacity

5

Seating Capacity

5

Horsepower

241 hp @ 5800 rpm

Horsepower

429 hp @ 6100 rpm

MPG City

21

MPG City

20

MPG Highway

31

MPG Highway

29
2021 Lexus IS
2021 Lexus IS
$39,050MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz S-Class
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now
2021 Lexus IS
$39,050MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP
$39,050
$109,800
Listings

Ratings & Reviews

User reviews

4.6

5.0

Expert reviews

7.3 out of 10

Read full review

7.5 out of 10

Read full review
Pros & cons

Pros

  • Stylish design

  • Multiple powertrain options

  • Great handling

Cons

  • Underwhelming base engine

  • Irritating transmission

  • Outdated technology

Pros

  • Powerful engine

  • Comfortable

  • Impressive technology

Cons

  • High price

Summary
The Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be.

The S-Class not only sits at the top of the Mercedes hierarchy in price and prestige, but it has also long served as a technological showcase. In the press release for the redesigned 2021 S-Class, Mercedes repeatedly noted the innovations—from anti-lock brakes to airbags—that were introduced on the big sedan and eventually trickled down to mainstream vehicles.

With the previous generation dating back to the 2014 model year (with a significant update for 2018), the Mercedes-Benz S-Class was in need of an update to maintain that status, and to keep pace with other full-size luxury sedans like the Audi A8, BMW 7 Series, and Lexus LS. To do that, the new S-Class gets a more sophisticated infotainment system, new powertrains, and more aerodynamic bodywork, among other features.

The 2021 S-Class launches in two configurations, both with 4Matic all-wheel drive (AWD) and EQ Boost mild-hybrid systems. The S500 4Matic has a six-cylinder engine, while the S580 4Matic has a V8. We spent a few days with the Mercedes-Benz S580 for this review. A Mercedes-Maybach S680 4Matic version will follow in the first half of 2022, and you can expect a new AMG performance version sometime in the future as well.

Video

Popular Features & Specs

Engine
2.0L 241 hp I4
3.0L 429 hp I6
Drive Train
RWD
AWD
Seating Capacity
5
5
Horsepower
241 hp @ 5800 rpm
429 hp @ 6100 rpm
MPG City
21
20
MPG Highway
31
29
Look and feel

2021 Lexus IS

8/10

2021 Mercedes-Benz S-Class

7/10

According to CarGurus experts, the 2021 Lexus IS is rated 8 out of 10, while the 2021 Mercedes-Benz S-Class is rated 7 out of 10.

The 2021 Lexus IS presents an athletically proportioned and elegantly designed sedan that captures motion even when standing still. Its interior boasts a tastefully simple dash and bold, assertive choices, reflecting a modern aesthetic. The IS also offers a new touchscreen infotainment system that supports Android Auto and Apple CarPlay.

On the other hand, the 2021 Mercedes-Benz S-Class features a classic exterior design with a drag coefficient of 0.22, indicating exceptional aerodynamics. Its interior is equipped with advanced technology, including a 12.3-inch digital instrument cluster and a 12.8-inch OLED central touchscreen, along with a 30-speaker Burmester audio system and rear-seat infotainment setup.

Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Picture of 2021 Lexus IS
Performance

2021 Lexus IS

7/10

2021 Mercedes-Benz S-Class

9/10

CarGurus experts rate the 2021 Lexus IS 7 out of 10 and the 2021 Mercedes-Benz S-Class 9 out of 10.

The 2021 Lexus IS offers a range of powertrains, including a 2.0-liter turbocharged engine and a 3.5-liter V6, delivering a balance of performance and efficiency. On the other hand, the 2021 Mercedes-Benz S-Class is powered by a 3.0-liter turbocharged inline-six engine in the S500 4Matic and a 4.0-liter twin-turbo V8 in the S580 4Matic, providing impressive horsepower and torque figures.

Form and function

2021 Lexus IS

7/10

2021 Mercedes-Benz S-Class

8/10

CarGurus experts rate the 2021 Lexus IS 7 out of 10 and the 2021 Mercedes-Benz S-Class 8 out of 10.

The 2021 Lexus IS offers a driver-centered focus on form and function, providing a comfortable and supportive seat, ample storage space, and adequate trunk space. In contrast, the 2021 Mercedes-Benz S-Class boasts increased front and rear headroom, more rear legroom, and a segment-leading shoulder room, along with luxurious power-adjustable front seats and a spacious center console.

Technology

2021 Lexus IS

7/10

2021 Mercedes-Benz S-Class

9/10

CarGurus experts rate the 2021 Lexus IS 7 out of 10 and the 2021 Mercedes-Benz S-Class 9 out of 10.

The 2021 Lexus IS now features a touchscreen infotainment system that supports Android Auto and Apple CarPlay, along with various connected services and a Mark Levinson premium surround-sound audio system. Meanwhile, the 2021 Mercedes-Benz S-Class offers an advanced MBUX infotainment system, augmented-reality head-up display, and personal profile setup with biometric or facial recognition.

Safety

2021 Lexus IS

7/10

2021 Mercedes-Benz S-Class

7/10

CarGurus experts rate the 2021 Lexus IS 7 out of 10 and the 2021 Mercedes-Benz S-Class 7 out of 10.

The 2021 Lexus IS comes equipped with Lexus Safety System+ 2.5, offering a comprehensive suite of driver-assist features, while the 2021 Mercedes-Benz S-Class features an industry-first rear-passenger airbag and a wide array of standard driver-assist features.

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for 2021 Lexus IS is 7.3 out of 10, while the 2021 Mercedes-Benz S-Class scores 7.5 out of 10. Based on these ratings, the 2021 Mercedes-Benz S-Class emerges as the slightly more favorable choice, offering advanced technology, luxurious interior features, and a focus on spaciousness and comfort.

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for 2021 Lexus IS is 7.3 out of 10, while the 2021 Mercedes-Benz S-Class scores 7.5 out of 10. Based on these ratings, the 2021 Mercedes-Benz S-Class emerges as the slightly more favorable choice, offering advanced technology, luxurious interior features, and a focus on spaciousness and comfort.

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By: CarGurus + AI

At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.

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