Used 2022 Mercedes-Benz S-Class for Sale near Portland, OR
164 results
![[799] MANUFAKTUR Diamond White Metallic 2022 Mercedes-Benz S-Class S 580 4MATIC AWD Sedan All-Wheel Drive Automatic](https://static.cargurus.com/images/forsale/2026/04/18/14/01/2022_mercedes-benz_s-class-pic-974518954080127668-1024x768.jpeg?io=true&width=640&height=480&fit=bounds&format=jpg&auto=webp)
CarGurus Analysis:
2022 Mercedes-Benz S-Class
- With 171 currently listed for sale near Portland, OR and an average price of $69,579.00, 19.3% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
- Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
93.0% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class sedan is the very model of modern executive transportation, boasting a sophisticated design, advanced hybrid powertrain options, and a wealth of cutting-edge technology.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall
Summary
- With 171 currently listed for sale near Portland, OR and an average price of $69,579.00, 19.3% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
- Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
93.0% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class sedan is the very model of modern executive transportation, boasting a sophisticated design, advanced hybrid powertrain options, and a wealth of cutting-edge technology.
Why it stands out
The 2022 Mercedes-Benz S-Class continues to solidify its status as an option for buyers seeking unparalleled luxury and performance in a full-size sedan. This model is equipped with a 48-volt mild hybrid gasoline-electric powertrain that enhances both efficiency and power, making it a leader in its class. The standard turbocharged 3.0-liter inline-six engine in the S500 generates 429 horsepower, while the S580's twin-turbocharged 4.0-liter V8 ups the ante even further. Drivers can expect quick acceleration and a thrilling driving experience, seamlessly complemented by a plush interior featuring high-quality materials and an impressive technology suite, including the intuitive MBUX infotainment system with a stunning 12.8-inch OLED display. Furthermore, the S-Class is renowned for its advanced safety features and driver assistance technologies, ensuring a safe and self-assured ride. While the price may seem daunting, the luxurious amenities and performance capabilities justify the investment for discerning buyers.
Other model years to consider
- Average price: $97,663.00
- Good/great deal percentage: 15.2%
- User rating: Not available
- Total listings: 184
- Average price: $31,077.00
- Good/great deal percentage: 13.8%
- User rating: 5 / 5
- Total listings: 123
- Average price: $45,743.00
- Good/great deal percentage: 21.7%
- User rating: 4.89 / 5
- Total listings: 92
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
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4.5 Overall rating
Filter by rating
Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
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