Used 2022 Mercedes-Benz GLS for Sale nearTampa, FL
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 79,580
- Stock #:
- D036586A
- VIN:
- 4JGFF5KE1NA588552


Sponsored by Audi Tampa
2022 Mercedes-Benz GLS
450 4MATIC
79,580 mi
$36,267
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 82,501
- Stock #:
- I655836
- VIN:
- 4JGFF5KE0NA655836

Sponsored Listing
2022 Mercedes-Benz GLS
450 4MATIC
82,501 mi
$35,667
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Gray
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 53,552
- Stock #:
- A812280
- VIN:
- 4JGFF8KE7NA812280

Sponsored Listing
2022 Mercedes-Benz GLS
AMG GLS 63 4MATIC
53,552 mi
$75,468
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 77,240
- Stock #:
- I451532
- VIN:
- 4JGFF8GE0MA451532

-$3,109
2021 Mercedes-Benz GLS
580 4MATIC
77,240 mi
$38,636
$37,612
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 58,887
- Stock #:
- CITTNA626087
- VIN:
- 4JGFF5KE5NA626087

2022 Mercedes-Benz GLS
450 4MATIC
58,887 mi
$42,190
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,476
- Stock #:
- LTEL09115A
- VIN:
- 4JGFF5KE2NA811469

2022 Mercedes-Benz GLS
450 4MATIC
48,476 mi
$44,328
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- MANUFAKTUR Cardinal Red Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 24,317
- Stock #:
- PH23177A
- VIN:
- 4JGFF8GE0PB005055

2023 Mercedes-Benz GLS
580 4MATIC
24,317 mi
$69,823
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 86,787
- Stock #:
- S022289A
- VIN:
- 4JGFF5KE4MA404090

2021 Mercedes-Benz GLS
450 4MATIC
86,787 mi
$30,989
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 84,002
- Stock #:
- T781022
- VIN:
- 4JGFF5KE6NA781022

2022 Mercedes-Benz GLS
450 4MATIC
84,002 mi
$30,894
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,043
- Stock #:
- 944834
- VIN:
- 4JGFF5KE2PA944834

-$1,400
2023 Mercedes-Benz GLS
450 4MATIC
30,043 mi
$54,880
$53,480
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 82,501
- Stock #:
- I655836
- VIN:
- 4JGFF5KE0NA655836

2022 Mercedes-Benz GLS
450 4MATIC
82,501 mi
$35,667
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 48,808
- Stock #:
- TNA649592
- VIN:
- 4JGFF5KE1NA649592

-$1,990
2022 Mercedes-Benz GLS
450 4MATIC
48,808 mi
$38,986
$37,986
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 79,580
- Stock #:
- D036586A
- VIN:
- 4JGFF5KE1NA588552

2022 Mercedes-Benz GLS
450 4MATIC
79,580 mi
$36,267
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 165 currently listed for sale near Tampa, FL and an average price of $48,385, 26.7% of 2022 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
92.7% of 2022 GLS models on CarGurus are accident free.
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 62,061
- Stock #:
- 7538
- VIN:
- 4JGFF5KE8PA900613

2023 Mercedes-Benz GLS
450 4MATIC
62,061 mi
$46,128
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 75,255
- Stock #:
- S017757M
- VIN:
- 4JGFF5KE8NA641537

2022 Mercedes-Benz GLS
450 4MATIC
75,255 mi
$37,843
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Manufaktur Diamond White Metallic
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- Automatic
- Mileage:
- 34,380
- Stock #:
- PA887643
- VIN:
- 4JGFF5KE5PA887643

2023 Mercedes-Benz GLS
450 4MATIC
34,380 mi
$52,218
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,859
- Stock #:
- TNT12611A
- VIN:
- 4JGFF5KE7NA804596

2022 Mercedes-Benz GLS
450 4MATIC
21,859 mi
$52,395
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 24,471
- Stock #:
- 5105
- VIN:
- 4JGFF8GE0MA566356

2021 Mercedes-Benz GLS
580 4MATIC
24,471 mi
$54,473
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 68,719
- Stock #:
- MA419540
- VIN:
- 4JGFF5KE7MA419540

2021 Mercedes-Benz GLS
450 4MATIC
68,719 mi
$33,637
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,655
- Stock #:
- CA985658
- VIN:
- 4JGFF8GE1PA985658

2023 Mercedes-Benz GLS
580 4MATIC
55,655 mi
$56,424
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 45,604
- Stock #:
- NA620836
- VIN:
- 4JGFF5KE1NA620836

2022 Mercedes-Benz GLS
450 4MATIC
45,604 mi
$42,990
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Gray
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 53,552
- Stock #:
- A812280
- VIN:
- 4JGFF8KE7NA812280

2022 Mercedes-Benz GLS
AMG GLS 63 4MATIC
53,552 mi
$75,468
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,043
- Stock #:
- 944834
- VIN:
- 4JGFF5KE2PA944834

-$1,400
Sponsored Listing
2023 Mercedes-Benz GLS
450 4MATIC
30,043 mi
$54,880
$53,480
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 165 currently listed for sale near Tampa, FL and an average price of $48,385, 26.7% of 2022 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
92.7% of 2022 GLS models on CarGurus are accident free.
Why it stands out
The 2022 Mercedes-Benz GLS sits at the top of Mercedes’ luxury SUV range and is the brand’s biggest SUV. Its “S” designation signals that it is meant to be the SUV equivalent of Mercedes’ flagship S-Class sedan, which helps explain why the GLS is positioned as a full-size luxury statement rather than just a practical family hauler. Mercedes also says the flagship SUV is big on both luxury and utility, and that combination is central to its appeal.
For 2022, Mercedes withdrew most of its V8 models from the United States, leaving only the base six-cylinder GLS 450 4Matic model. That makes this version of the GLS notable for being the only one available at the time of testing, and it still brings the strengths highlighted in the test drive data: stylish design, a powerful engine, and a spacious cabin. Those qualities make it easy to see why buyers would be drawn to it if they want a large, upscale SUV with a strong presence and plenty of room.
The tradeoffs are just as important. The test drive data points to poor ride quality, advanced safety features that are not standard, and poor ergonomic design. So while the 2022 Mercedes-Benz GLS stands out for luxury, size, and utility, it also asks buyers to accept some comfort and usability compromises.
Other model years to consider
- Average price: $71,490
- Good/great deal percentage: 25.0%
- User rating: 5 / 5
- Total listings: 216
- Average price: $59,618
- Good/great deal percentage: 26.7%
- Total listings: 180
- Average price: $105,504
- Good/great deal percentage: 25.2%
- Total listings: 206
This analysis is based on CarGurus' proprietary market data from September 28, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
See more price trends2022 Mercedes-Benz GLS Pricing Analysis: Tampa, FL Market Report
Pricing by Nearby Locations
Market Area: Tampa, FL
Key Insights
- Highest Price in Crystal River: The city of Crystal River has the highest average price at $77,000, likely due to limited inventory and higher demand for luxury vehicles.
- Lowest Prices in Fort Myers: Fort Myers offers the lowest average price at $40,773, indicating a more price-sensitive market or higher inventory turnover.
- Inventory Distribution: Cities like Lakeland (165 listings) and Brooksville (163 listings) show a healthy inventory, which correlates with average prices around $47,000, suggesting stable demand.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Crystal River, FL | 163 | $77,000 |
| Brooksville, FL | 163 | $49,160 |
| Lakeland, FL | 165 | $47,413 |
| Sarasota, FL | 151 | $46,493 |
| Leesburg, FL | 160 | $50,186 |
| North Port, FL | 149 | $47,423 |
| Orlando, FL | 156 | $44,776 |
| Ocala, FL | 164 | $42,191 |
| Fort Myers, FL | 140 | $40,773 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 450 4MATIC is the most common trim with 353 listings, indicating strong demand for this model.
- Price Range: The 580 4MATIC trim, priced at $101,250 MSRP, reflects a premium offering, while the 450 4MATIC serves as a more accessible option at $77,850 MSRP.
- High-End Luxury: The 600 Mercedes-Maybach 4MATIC trim, with an MSRP of $165,100, represents the luxury segment, appealing to buyers seeking top-tier features and performance.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 353 | $77,850 | AWD | 3.0L 362 hp I6 |
| 580 4MATIC | 50 | $101,250 | AWD | 4.0L 483 hp V8 |
| AMG GLS 63 4MATIC | 65 | $135,400 | AWD | 4.0L 603 hp V8 |
| 600 Mercedes-Maybach 4MATIC | 59 | $165,100 | AWD | 4.0L 550 hp V8 |
Pricing Analysis by Model Year
Key Insights
- New Models at Premium Prices: The 2025 Mercedes-Benz GLS is priced at $104,829, which is approximately 17.5% above its MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2019 model shows a steep decline, priced at $26,990, which is about -61.5% compared to its original MSRP, reflecting typical depreciation trends.
- Best Value in Recent Models: The 2021 model is priced at $49,423, representing a -34.5% depreciation, making it a potentially attractive option for buyers looking for a balance of price and features.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Mercedes-Benz GLS | $90,250 | $92,208 | +2.2% |
| 2025 Mercedes-Benz GLS | $89,200 | $104,829 | +17.5% |
| 2024 Mercedes-Benz GLS | $87,000 | $72,628 | -16.4% |
| 2023 Mercedes-Benz GLS | $81,800 | $58,018 | -29.1% |
| 2021 Mercedes-Benz GLS | $76,000 | $49,423 | -34.5% |
| 2020 Mercedes-Benz GLS | $75,200 | $34,027 | -54.7% |
| 2019 Mercedes-Benz GLS | $70,150 | $26,990 | -61.5% |
| 2018 Mercedes-Benz GLS | $69,550 | $19,948 | -71.3% |
| 2017 Mercedes-Benz GLS | $67,050 | $20,706 | -69.1% |
These recommendations are based on CarGurus' proprietary market data from September 23, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2022 Mercedes-Benz GLS cost?
| Metric | Value |
|---|---|
| Current Average Price | $46,871 |
| Year-Round Low | $46,871 |
| Year-Round High | $55,166 |
| Average Price a Year Ago | $55,157 |
| Change vs. Last Year | −15.02% |
Prices have softened 15.02% compared to this time last year, making it a favorable time to shop this model year.
There are 852 listings available, which suggests you have a decent amount of inventory to compare.
Is the 2022 Mercedes-Benz GLS a good car?
Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.33/10 expert rating. The standout strength is Look and feel at 9/10.
It sits at the top of Mercedes’ luxury SUV range and is positioned as the brand’s flagship three-row SUV, so you’re shopping for a full-size luxury statement rather than a simple family hauler. The test-drive data backs up that positioning with a stylish design, a powerful engine, and a spacious cabin.
The trade-offs are worth weighing: poor ride quality and poor ergonomic design are both called out, and advanced safety features are not standard. Even so, 36.2% of listings are priced as good or great deals, which gives you some room to shop selectively.
Is the 2022 Mercedes-Benz GLS reliable?
Owners rate it 5/5, a strong signal of long-term satisfaction.
The GLS is described as a solid luxury SUV with a strong luxury-first character, and the inline-six powertrain is presented as smooth and well suited to a premium vehicle. The mild-hybrid setup also helps the engine work more efficiently by reducing its workload and supporting accessories.
Mercedes’ four-year, 50,000-mile basic and powertrain warranties add some reassurance for used buyers. Still, long-term ownership risk comes down to whether you’re comfortable with a large, complex luxury SUV that may carry higher repair and maintenance exposure once warranty coverage ends.
What should I look for when buying a used 2022 Mercedes-Benz GLS?
Accident-free inventory is solid at 87.8% — always verify the vehicle history report.
You should still run a history report on any candidate and prioritize a pre-purchase inspection, especially on a large luxury SUV with available options that can vary widely from one example to the next. Focus on overall condition, signs of prior damage, and whether the equipment on the listing matches what you expect from the trim and options shown.
Key things to evaluate:
- Trim level: The base GLS 450 has a fairly basic interior by GLS standards, but it still feels properly luxurious with leather upholstery, a panoramic roof, ambient lighting, and a digital instrument cluster paired with the infotainment screen. It is the only version available in this model year’s U.S. market, so there isn’t a higher standard trim to compare against here.
- Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline-six with a nine-speed automatic and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft available in short bursts.
- Safety package: Standard equipment includes forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features cost extra.
- Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM satellite radio, and natural-language voice recognition. A head-up display is optional.
- Fuel efficiency: EPA ratings are 20 mpg combined, 18 mpg city, and 24 mpg highway.
Which 2022 Mercedes-Benz GLS trim should I buy?
The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.
Here's the short version:
The GLS 450 4Matic: This is the only U.S. trim for 2022, so your decision is less about choosing among trims and more about choosing the right example. It gives you the core GLS strengths: a smooth inline-six, standard AWD, air suspension, a surround-view camera system, and a well-appointed cabin. It also carries the model’s main compromises, including the fact that some key safety and comfort features still cost extra.
Mercedes still leaves some advanced driver-assistance features as options, so check each listing carefully for the safety equipment you want.
Is now a good time to buy a used 2022 Mercedes-Benz GLS?
This looks like a moderate, selective buyer’s market, so you can shop carefully and still find worthwhile listings.
- Deal availability: 36.2% of listings are priced as good or great deals.
- Inventory: There are 852 listings available.
- Price trend: Prices have softened 15.02% compared with last year.
- Clean inventory: 87.8% of listings are accident-free.
If you find a listing below $46,871, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2022 Mercedes-Benz GLS's resale value?
The current average of $46,871 sits slightly below last year's $55,157.
That price movement suggests the market has already adjusted downward, which can help you buy at a more favorable point in the cycle. For a future seller, it also means resale value may depend heavily on condition, mileage, and equipment because the broader market has softened.
Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.
Is the 2022 Mercedes-Benz GLS safe?
It earns a 6/10 safety score from our experts.
Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also includes a system that emits “pink noise” to help protect ears during a collision.
You should note that adaptive cruise control, lane-keep assist, second-row side airbags, and several more advanced driver-assistance features are optional rather than standard. That means you’ll want to verify the exact safety equipment on any used example before you buy.
Should I buy a 2022 Mercedes-Benz GLS or consider a different year?
If you're weighing the 2022 against nearby model years, here's how to think about it:
Choose the 2022 if:
- 36.2% of listings are priced as good or great deals.
- Accident-free inventory is solid at 87.8% — always verify the vehicle history report.
- Price trend: Prices have softened 15.02% compared with last year.
- Owners rate it 5/5 — a strong satisfaction signal.
- Mercedes withdrew most V8 models for this year, leaving the GLS 450 as the only U.S. version at the time of testing.
Consider the 2021 if:
- At $46,213, the 2021 costs less than the current year's $46,871 average.
- It emphasizes comfort and upscale presentation with spacious seating and plenty of cargo space.
The bottom line: If you want the current-year GLS at a softer price point, the 2022 is the better primary target because it combines strong inventory, a lower average price than last year, and solid owner satisfaction. If you’re focused mainly on saving money, the 2021 is the better value play, especially if you find one in strong condition with the equipment you want.
These recommendations are based on CarGurus' proprietary market data from September 29, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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