Used 2022 Mercedes-Benz GLS for Sale nearKnoxville, TN

How much does the 2022 Mercedes-Benz GLS cost?

Prices have softened 15.39% compared to this time last year, making it a favorable time to shop this model year.

There are 900 listings available, which suggests you have a decent amount of inventory to compare.

Is the 2022 Mercedes-Benz GLS a good car?

Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.3/10 expert rating. The standout strength is Look and feel at 9/10.

It fits buyers who want a large, upscale family vehicle with a premium badge, and its three-row layout and flagship positioning reinforce that role. The GLS also brings a stylish design, a powerful engine, and a spacious cabin, which support its luxury-and-utility mission.

The trade-offs are a poor ride quality and ergonomic design, plus advanced safety features that are not standard. Even so, the market still shows 40.1% of listings as good or great deals, which is a healthy sign of value availability.

Is the 2022 Mercedes-Benz GLS reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The GLS is presented as a flagship luxury SUV with a strong comfort-and-space mission, and its six-cylinder powertrain is described as smooth and well suited to luxury use. The mild-hybrid assist also helps the engine feel more refined in everyday driving.

Mercedes’ EQ Boost system adds electric assistance, and the engine start/stop behavior is described as more aggressive while the electric motor also helps power accessories and reduce engine workload. Mercedes also offers a four-year, 50,000-mile basic warranty and a four-year, 50,000-mile powertrain warranty.

For used buyers, the main long-term ownership risk is that a large, complex luxury SUV can become expensive if neglected, so service history matters.

What should I look for when buying a used 2022 Mercedes-Benz GLS?

Accident-free inventory is solid at 86.1% — always verify the vehicle history report.

You should still run a history report on every candidate and prioritize a pre-purchase inspection, especially on a vehicle with luxury features and complex systems. Focus on overall condition, service records, and whether the ride, electronics, and cabin controls feel consistent with a well-kept flagship SUV.

Key things to evaluate:

• Trim level: The base GLS 450 form is more subtle and less flashy than some rivals, and the test vehicle’s fairly basic interior lacked reclining seats. It still felt luxurious thanks to leather upholstery, a panoramic roof, ambient lighting, and a well-integrated digital cockpit.
• Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline six with a nine-speed automatic and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, and the electric motor can add 21 hp and 184 lb-ft in short bursts.
• Safety package: Standard equipment includes forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features cost extra.
• Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM satellite radio, and natural-language voice recognition. A head-up display is optional.
• Fuel efficiency: EPA ratings are 18 mpg city and 24 mpg highway, or 20 mpg combined.

Which 2022 Mercedes-Benz GLS trim should I buy?

The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.

Here's the short version:

The GLS 450 4Matic is the only version available for this model year, so your decision is mostly about whether the standard equipment and flagship-size packaging fit your needs. It brings the smooth inline-six powertrain, standard AWD, air suspension, and a surround-view camera system, which makes it the clear choice for shoppers who want the core GLS experience without waiting for higher-output variants to return.

Mercedes notes that some key features, including leather seating and adaptive cruise control, are not standard on this flagship SUV.

Is now a good time to buy a used 2022 Mercedes-Benz GLS?

It looks like a buyer’s market for this model year, with meaningful price softness and a solid pool of listings to compare.

• Deal availability: 40.1% of listings are priced as good or great deals.
• Inventory: There are 900 listings available.
• Price trend: Prices have softened 15.39% compared with last year.
• Clean inventory: 86.1% of listings are accident-free.

If you find a listing below $45,466, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz GLS's resale value?

The current average of $45,466 sits slightly below last year's $53,737.

That decline suggests the market has already adjusted downward, which can help future buyers but may pressure resale returns if you sell soon. If you buy at the current average or below, you may have less depreciation risk than someone who paid closer to last year’s pricing.

The GLS still has the kind of flagship appeal that can support demand, especially for shoppers who want a large luxury SUV with a premium badge and strong space. Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz GLS safe?

It earns a 6/10 safety score from our experts.

Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also includes a feature that emits pink noise during a collision to help protect hearing.

You should note that adaptive cruise control, lane-keep assist, second-row side airbags, and several more advanced driver-assistance features are optional rather than standard. That means you need to check carefully for the equipment you want on any used example.

Should I buy a 2022 Mercedes-Benz GLS or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 40.1% of listings are priced as good or great deals.
• Accident-free inventory is solid at 86.1% — always verify the vehicle history report.
• Price trend: Prices have softened 15.39% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• Mercedes withdrew most V8 models for this year, leaving the base six-cylinder GLS 450 as the only version available.

Consider the 2021 if:

• At $45,367, the 2021 costs less than the current year's $45,466 average.
• It emphasizes comfort above all else while still offering three rows of spacious seating.

The bottom line: The 2022 is the better pick if you want the current-year market softness, strong inventory, and the only GLS version available at the time of testing. If you’re mainly chasing the lowest entry price, the 2021 is worth a look, but the 2022 gives you the cleaner buying case right now.

How does the 2022 Mercedes-Benz GLS compare to the 2022 BMW X7?

These recommendations are based on CarGurus' proprietary market data from November 10, 2026, CarGurus experts' opinions, and generative AI.