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Used 2022 Lexus RX for Sale near Port Saint Lucie, FL

160 results
Port Saint Lucie, FL
2023 Lexus RX 350 FWD Taverna INFINITI North Miami

2023 Lexus RX

350 FWD

39,057 miles

$40,512

Fair Deal
West Park, FL
89 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Mica
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Macadamia W/Black Cascade
Transmission:
8-Speed Automatic
Mileage:
39,057
Stock number:
NV007074
VIN:
2T2BAMBA9PC007074

Sponsored

2023 Lexus RX 350 Premium FWD

2023 Lexus RX

350 Premium FWD

43,096 miles

$41,578

Fair Deal
Miami, FL
92 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red (Copper Crest)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Palomino
Transmission:
8-Speed Automatic
Mileage:
43,096
Stock number:
D047573A
VIN:
2T2BAMBA3PC011752

Sponsored

2022 Lexus RX 350L FWD

2022 Lexus RX

350L FWD

121,946 miles

$24,500

Great Deal
West Palm Beach, FL
34 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
121,946
Stock number:
HTLH2026678
VIN:
JTJHZKEA4N2026678

Sponsored

2022 Lexus RX 350L FWD

2022 Lexus RX

350L FWD

26,779 miles

$42,997

Fair Deal
Store transfer to Jensen Beach, FL
2,309 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
CREAM
Transmission:
Automatic
Mileage:
26,779
Stock number:
28146572
VIN:
JTJHZKEA8N2029048

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

35,671 miles

$38,000

Great Deal
Delray Beach, FL
59 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
35,671
Stock number:
PCD7115A
VIN:
2T2YZMDA8NC311994

2022 Lexus RX 350L FWD

2022 Lexus RX

350L FWD

121,946 miles

$24,500

Great Deal
West Palm Beach, FL
34 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
121,946
Stock number:
HTLH2026678
VIN:
JTJHZKEA4N2026678

Preparing for a close up...

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2021 Lexus RX

350 FWD

44,840 miles

$30,299

Great Deal
Pompano Beach, FL
68 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
44,840
Stock number:
C202539
VIN:
2T2HZMAA5MC202539

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2023 Lexus RX

350 Premium FWD

35,710 miles

$38,990

Good Deal
Miami, FL
90 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Palomino
Transmission:
8-Speed Automatic
Mileage:
35,710
Stock number:
011256F01
VIN:
JTJCHMAA0P2011256

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2022 Lexus RX

350 FWD

7,021 miles

$39,479

Good Deal
Coconut Creek, FL
68 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
7,021
Stock number:
9295236A
VIN:
2T2HZMAA6NC219254

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2022 Lexus RX

350 FWD

52,479 miles

$36,997

Fair Deal
Store transfer to Jensen Beach, FL
2,293 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic Overdrive
Mileage:
52,479
Stock number:
28142708
VIN:
2T2AZMAA5NC233566

Preparing for a close up...

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2022 Lexus RX

350 F Sport Handling AWD

35,708 miles

$42,000

Fair Deal
Stuart, FL
12 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
35,708
Stock number:
NC340368P
VIN:
2T2YZMDA7NC340368

Preparing for a close up...

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2023 Lexus RX

350 Premium FWD

30,576 miles

$43,788

Good Deal
Certified Pre-Owned
North Miami, FL
94 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Palomino
Transmission:
8-Speed Automatic
Mileage:
30,576
Stock number:
26054401
VIN:
2T2BAMBA1PC006680

Preparing for a close up...

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2021 Lexus RX

350 FWD

57,484 miles

$28,990

Great Deal
Fort Lauderdale, FL
80 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Obsidian)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
57,484
Stock number:
PN2597A
VIN:
2T2HZMAA4MC210213

Preparing for a close up...

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2023 Lexus RX

350 FWD

35,199 miles

$36,997

Good Deal
Oakland Park, FL
76 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Silver
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
35,199
Stock number:
U010101
VIN:
2T2BAMBA1PC010101

Preparing for a close up...

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2022 Lexus RX

350 FWD

36,073 miles

$35,875

Good Deal
Delray Beach, FL
58 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
Automatic
Mileage:
36,073
Stock number:
NC231502
VIN:
2T2HZMAA4NC231502

Preparing for a close up...

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2022 Lexus RX

350 F Sport Handling AWD

31,008 miles

$42,388

Good Deal
Certified Pre-Owned
North Miami, FL
94 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
31,008
Stock number:
26038402
VIN:
2T2YZMDA3NC335782

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2021 Lexus RX

350 F Sport AWD

49,846 miles

$38,297

Fair Deal
Store transfer to Jensen Beach, FL
473 mi away • Price includes $299 shipping Price includes $299 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
49,846
Stock number:
28198194
VIN:
2T2SZMDA8MC263028

Preparing for a close up...

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2022 Lexus RX

350 F Sport Handling AWD

28,547 miles

$41,588

Fair Deal
Delray Beach, FL
59 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
28,547
Stock number:
PN1060
VIN:
2T2YZMDA7NC326857

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Photos coming soon

2023 Lexus RX

350 Premium FWD

8,871 miles

$46,788

Good Deal
Certified Pre-Owned
North Miami, FL
94 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Matador Red Mica
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
8,871
Stock number:
25512801
VIN:
JTJCHMAA8P2003325

Preparing for a close up...

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2023 Lexus RX

350 F Sport Handling AWD

24,245 miles

$45,988

Good Deal
Deerfield Beach, FL
68 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Grecian Water
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
24,245
Stock number:
PC017971
VIN:
2T2BAMCA3PC017971

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / Florida
  6. / Port Saint Lucie
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX

Summary

  • With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
  • 84.2% of 2022 RX models on CarGurus are accident free.
  • The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Port Saint Lucie, FL?

The average 2022 Lexus RX costs about $39,936.21. The average price has decreased by -4.9% since last year. The 124 for sale near Port Saint Lucie, FL on CarGurus, range from $21,562 to $55,125 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Port Saint Lucie, FL have no reported accidents or damage?

121 out of 124 for sale near Port Saint Lucie, FL have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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