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Used 2022 Lexus RX for Sale near Missouri

117 results
Kansas City, MO
2022 Lexus RX 350 AWD Metro Ford, Inc.

2022 Lexus RX

350 AWD

20,085 miles

$44,100

Good Deal
Independence, MO
9 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
20,085
Stock number:
P9405
VIN:
2T2HZMDA9NC367068

Sponsored

2023 Lexus RX 350 Premium AWD

2023 Lexus RX

350 Premium AWD

25,259 miles

$47,989

Fair Deal
Kansas City, MO
10 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Macadamia
Transmission:
Automatic
Mileage:
25,259
Stock number:
T00215A
VIN:
2T2BAMCA9PC016081

Sponsored

2023 Lexus RX 350 AWD

2023 Lexus RX

350 AWD

53,536 miles

$45,500

Fair Deal
Kansas City, MO
4 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
53,536
Stock number:
P14100
VIN:
2T2BAMCA5PC022265

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

37,970 miles

$37,347

Good Deal
Store transfer to Overland Park, KS
478 mi away • Price includes $349 shipping Price includes $349 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Green
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
37,970
Stock number:
28144060
VIN:
2T2AZMAA0MC218875

2022 Lexus RX 350 AWD

2022 Lexus RX

350 AWD

33,900 miles

$40,988

Fair Deal
Olathe, KS
20 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar (223))
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black W/Matte Walnut Trim (ea29)
Transmission:
8-Speed Automatic
Mileage:
33,900
Stock number:
553111A
VIN:
2T2HZMDA3NC339055

2022 Lexus RX 350L AWD

2022 Lexus RX

350L AWD

56,269 miles

$39,197

Good Deal
Store transfer to Overland Park, KS
173 mi away • Price includes $199 shipping Price includes $199 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
56,269
Stock number:
27993678
VIN:
JTJHZKFA1N2040892

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport AWD

18,301 miles

$45,498

Good Deal
Certified Pre-Owned
Kansas City, MO
13 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
Automatic
Mileage:
18,301
Stock number:
P7752
VIN:
2T2SZMDA7NC365826

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport Handling AWD

48,387 miles

$41,853

Fair Deal
Olathe, KS
21 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
48,387
Stock number:
S82511
VIN:
2T2YZMDA4MC282511

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

20,085 miles

$44,100

Good Deal
Independence, MO
9 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
20,085
Stock number:
P9405
VIN:
2T2HZMDA9NC367068

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

82,399 miles

$35,600

Fair Deal
Overland Park, KS
9 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Cloudburst Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
82,399
Stock number:
K06102A
VIN:
2T2HZMDAXNC328179

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium AWD

25,259 miles

$47,989

Fair Deal
Kansas City, MO
10 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Macadamia
Transmission:
Automatic
Mileage:
25,259
Stock number:
T00215A
VIN:
2T2BAMCA9PC016081

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport AWD

48,289 miles

$39,292

Good Deal
Kansas City, MO
10 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
48,289
Stock number:
T62333A
VIN:
2T2SZMDA7MC298255

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / Missouri
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX

Summary

  • With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
  • 84.2% of 2022 RX models on CarGurus are accident free.
  • The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Missouri?

The average 2022 Lexus RX costs about $39,904.35. The average price has decreased by -4.9% since last year. The 117 for sale near Missouri on CarGurus, range from $27,484 to $54,845 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Missouri have no reported accidents or damage?

117 out of 117 for sale near Missouri have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Missouri

  • 2024 Lexus RX in Missouri

  • 2023 Lexus RX

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