Used 2022 Lexus RX for Sale near Saint Louis, MO
114 results
CarGurus Analysis:
2022 Lexus RX
With 110 currently listed for sale near Saint Louis, MO and an average price of $37,717.00, 88.2% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.75 / 5 stars.
100.0% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX features a luxurious interior, advanced safety systems, and delivers high driving comfort, making it a popular choice among luxury crossover SUVs.
CarGurus Analysis: 2022 Lexus RX
overall
Summary
With 110 currently listed for sale near Saint Louis, MO and an average price of $37,717.00, 88.2% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.75 / 5 stars.
100.0% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX features a luxurious interior, advanced safety systems, and delivers high driving comfort, making it a popular choice among luxury crossover SUVs.
Why it stands out
The 2022 Lexus RX distinguishes itself in the competitive midsize luxury SUV segment with its rich comfort, stylish design, and a reputation for reliability. Owners appreciate the plush interiors and innovative tech features that enhance the driving experience, perfectly merging luxury with functionality. While the RX offers a smooth driving experience with a 3.5-liter V6 engine that delivers 295 horsepower, it lacks the sporty performance some may expect. However, its design remains attractive, featuring sharp character lines and modern aesthetics that set it apart from competitors. The RX is well-equipped with advanced safety technology, ensuring peace of mind for drivers and passengers alike. With options for a hybrid model, the 2022 RX also caters to those seeking better fuel efficiency without compromising on luxury.
Other model years to consider
- Average price: $48,484.00
- Good/great deal percentage: 74.6%
- User rating: 5 / 5
- Total listings: 126
- Average price: $23,110.00
- Good/great deal percentage: 56.2%
- User rating: 4.62 / 5
- Total listings: 130
- Average price: $27,650.00
- Good/great deal percentage: 67.9%
- User rating: 5 / 5
- Total listings: 84
This analysis is based on CarGurus' proprietary market data from May 5, 2026, CarGurus experts' opinions, and generative AI.
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4.8 Overall rating
Filter by rating
Marc G
Reviewed a 2022 Lexus RX on Dec 29, 2025
Good and reliable vehicle. Luxury is the cornerstone of this SUV.
Terry C
Reviewed a 2022 Lexus RX on Apr 12, 2025
Non turbo Toyota reliability and smoothness and composure of a S class.
Uday T
Reviewed a 2022 Lexus RX on Jun 6, 2023
Great car, drives smooth. Lacks pick up power for a V6
Anonymous
Reviewed a 2022 Lexus RX on Feb 19, 2024
I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!
2022 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport Handling FWD | $51,800 |
| 350L Luxury FWD | $54,750 |
| 350 F Sport AWD | $50,800 |
| 350L FWD | $48,750 |
| 350L AWD | $50,150 |
| 350 F Sport Handling AWD | $53,200 |
| 350 AWD | $47,320 |
| 350 FWD | $45,920 |
2022 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus RX prices has changed over time.
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