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Used 2022 Lexus RX for Sale near Saint Louis, MO

105 results
Saint Louis, MO
2023 Lexus RX 350 Premium+ AWD Spirit Lexus

2023 Lexus RX

350 Premium+ AWD

10,444 miles

$49,500

Good Deal
Certified Pre-Owned
St. Louis, MO
12 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
10,444
Stock number:
P2N001864
VIN:
2T2BAMCAXPC001864

Sponsored

2022 Lexus RX 350 AWD

2022 Lexus RX

350 AWD

90,535 miles

$34,000

Fair Deal
Saint Charles, MO
22 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
90,535
Stock number:
A16521M
VIN:
2T2HZMDA0NC312461

Sponsored

2022 Lexus RX 350 AWD

2022 Lexus RX

350 AWD

42,542 miles

$38,600

Good Deal
Saint Charles, MO
22 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
42,542
Stock number:
A16235M
VIN:
2T2HZMDA9NC366552

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

67,490 miles

$33,447

Good Deal
Store transfer to Saint Louis, MO
509 mi away • Price includes $449 shipping Price includes $449 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
67,490
Stock number:
28103054
VIN:
2T2AZMAA0MC195775

2022 Lexus RX 350 AWD

2022 Lexus RX

350 AWD

32,641 miles

$37,897

Great Deal
Chesterfield, MO
25 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Green
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
32,641
Stock number:
YNC34459
VIN:
2T2AZMDA9NC344598

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 FWD

24,419 miles

$41,747

Great Deal
Store transfer to Saint Louis, MO
889 mi away • Price includes $749 shipping Price includes $749 shipping
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
White
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
24,419
Stock number:
28395877
VIN:
2T2BAMBA1PC010079

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium+ FWD

32,530 miles

$47,600

Good Deal
Certified Pre-Owned
St. Louis, MO
12 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
White
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
32,530
Stock number:
P2N006557
VIN:
JTJCHMAA0P2006557

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium+ AWD

10,444 miles

$49,500

Good Deal
Certified Pre-Owned
St. Louis, MO
12 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
10,444
Stock number:
P2N001864
VIN:
2T2BAMCAXPC001864

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 AWD

34,984 miles

$44,490

Good Deal
Certified Pre-Owned
Ballwin, MO
19 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
34,984
Stock number:
7759551
VIN:
2T2BAMCA1PC037121

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

42,542 miles

$38,600

Good Deal
Saint Charles, MO
22 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
42,542
Stock number:
A16235M
VIN:
2T2HZMDA9NC366552

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

22,538 miles

$43,926

Fair Deal
Manchester, MO
15 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
22,538
Stock number:
31885A
VIN:
2T2HZMDA4NC330817

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium AWD

36,555 miles

$49,640

Fair Deal
Certified Pre-Owned
Manchester, MO
15 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Macadamia
Transmission:
8-Speed Automatic
Mileage:
36,555
Stock number:
35985B
VIN:
2T2BAMCA9PC020521

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium AWD

18,390 miles

$47,662

Fair Deal
Hazelwood, MO
14 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Birch Leather
Transmission:
Automatic
Mileage:
18,390
Stock number:
PBT4756
VIN:
2T2BAMCA9PC036797

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium AWD

29,248 miles

$46,700

Fair Deal
Certified Pre-Owned
St. Louis, MO
12 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
29,248
Stock number:
P2P027870
VIN:
2T2BAMCA3PC027870

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

32,641 miles

$37,897

Great Deal
Chesterfield, MO
25 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Green
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
32,641
Stock number:
YNC34459
VIN:
2T2AZMDA9NC344598

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / Missouri
  6. / Saint Louis
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX ## Summary - With 2,069 currently listed for sale on CarGurus and an **average price of $39,701.00**, 31.5% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Lexus RX 4.58 / 5 stars and CarGurus experts gave it an 7.33 / 10. - **84.4% of 2022 Lexus RX models on CarGurus are accident free**. - The 2022 Lexus RX maintains its reputation as a best-seller due to its attractive design, luxury amenities, and driving comfort, bolstered by tried-and-true reliability. ## Why it stands out The 2022 Lexus RX distinguishes itself in the crowded midsize luxury crossover segment with its blend of style, comfort, and advanced technology. Although it doesn’t excel in performance, it continues to attract buyers with a modern exterior that features distinct character lines and sporty accents, making it visually appealing compared to competitors like the Audi Q5 and BMW X5. This iteration builds on minimal changes from previous years, ensuring familiar luxury while incorporating new color options. Inside, the RX exudes a high-quality feel with multiple interior configurations, although some users have noted that the ergonomics could use improvement. The ride quality is highly praised for its smoothness, making it a great choice for long drives, while the quiet cabin adds to the overall comfort. ## Other model years to consider - **[2023 Lexus RX](https://www.cargurus.com/Cars/l-Used-2023-Lexus-RX-c32334)** - Average price: $46,857.00 - Good/great deal percentage: 32.0% - User rating: 4.62 / 5 - Total listings: 2,455 - **[2021 Lexus RX](https://www.cargurus.com/Cars/l-Used-2021-Lexus-RX-c30886)** - Average price: $35,529.00 - Good/great deal percentage: 33.1% - User rating: 4.73 / 5 - Total listings: 1,342 - **[2020 Lexus RX](https://www.cargurus.com/Cars/l-Used-2020-Lexus-RX-c29337)** - Average price: $32,768.00 - Good/great deal percentage: 34.6% - User rating: 4.77 / 5 - Total listings: 1,105 This analysis is based on CarGurus' proprietary market data from March 2, 2026, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Saint Louis, MO?

The average 2022 Lexus RX costs about $39,850.94. The average price has decreased by -3.4% since last year. The 105 for sale near Saint Louis, MO on CarGurus, range from $28,394 to $55,998 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Saint Louis, MO have no reported accidents or damage?

105 out of 105 for sale near Saint Louis, MO have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Saint Louis MO

  • 2024 Lexus RX in Saint Louis MO

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  • Lexus RX 350 FWD in Saint Louis MO

  • Lexus RX 350 AWD

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