Used 2021 Lexus RX for Sale near Saint Louis, MO
73 results
CarGurus Analysis:
2021 Lexus RX
With 75 currently listed for sale near Saint Louis, MO and an average price of $41,043.00, 90.7% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars.
100.0% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX features luxurious accommodations, a reliable V6 engine, and a suite of advanced safety systems that enhance its overall appeal.
CarGurus Analysis: 2021 Lexus RX
overall
Summary
With 75 currently listed for sale near Saint Louis, MO and an average price of $41,043.00, 90.7% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars.
100.0% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX features luxurious accommodations, a reliable V6 engine, and a suite of advanced safety systems that enhance its overall appeal.
Why it stands out
The 2021 Lexus RX continues to be a top contender in the luxury SUV segment, thanks to its combination of reliability, comfort, and an impressive level of standard features. It boasts a 3.5-liter V6 engine that produces 295 horsepower, paired with a smooth eight-speed automatic transmission, providing ample power while maintaining a comfortable ride. The RX is well-equipped with technology that enhances driving convenience and safety, including Lexus Safety System+ 2.0, ensuring top-notch protection for its occupants. While some may find the infotainment system less intuitive compared to competitors, the RX compensates with a high-quality interior and a reputation for luxury and longevity that appeals to many buyers. Moreover, its accident-free record and high owner satisfaction ratings underscore its reliability and desirability in the used car market.
Other model years to consider
- Average price: $48,484.00
- Good/great deal percentage: 74.6%
- User rating: 5 / 5
- Total listings: 126
- Average price: $37,717.00
- Good/great deal percentage: 88.2%
- User rating: 4.75 / 5
- Total listings: 110
- Average price: $23,110.00
- Good/great deal percentage: 56.2%
- User rating: 4.62 / 5
- Total listings: 130
This analysis is based on CarGurus' proprietary market data from May 5, 2026, CarGurus experts' opinions, and generative AI.
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5.0 Overall rating
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Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury FWD | $54,050 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport AWD | $50,100 |
| 350 F Sport Handling AWD | $52,500 |
| 350 FWD | $45,220 |
| 350 AWD | $46,620 |
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
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