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Used 2022 Lexus IS for Sale near Myrtle Beach, SC

101 results
Myrtle Beach, SC
2022 Lexus IS 350 F Sport RWD Simons Chevrolet GMC

2022 Lexus IS

350 F Sport RWD

41,361 miles

$37,991

Fair Deal
Whiteville, NC
43 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Brown (Beige)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
8-Speed Automatic
Mileage:
41,361
Stock number:
PC1005B
VIN:
JTHGZ1B25N5057683

Sponsored

2023 Lexus IS 350 F Sport RWD

2023 Lexus IS

350 F Sport RWD

16,542 miles

$43,300

Good Deal
Summerville, SC
86 mi away
Year:
2023
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
16,542
Stock number:
AD1175
VIN:
JTHGZ1B29P5070939

Sponsored

2023 Lexus IS 350 F Sport RWD

2023 Lexus IS

350 F Sport RWD

24,657 miles

$41,300

Fair Deal
Burgaw, NC
81 mi away
Year:
2023
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Cloudburst Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
24,657
Stock number:
8380XP
VIN:
JTHGZ1B25P5064779

Sponsored

2021 Lexus IS 350 F Sport RWD

2021 Lexus IS

350 F Sport RWD

61,244 miles

$35,097

Good Deal
Store transfer to Myrtle Beach, SC
184 mi away • Price includes $99 shipping Price includes $99 shipping
Year:
2021
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Red
Transmission:
Automatic
Mileage:
61,244
Stock number:
27965885
VIN:
JTHGZ1B27M5044111

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

41,361 miles

$37,991

Fair Deal
Whiteville, NC
43 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Brown (Beige)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
8-Speed Automatic
Mileage:
41,361
Stock number:
PC1005B
VIN:
JTHGZ1B25N5057683

Preparing for a close up...

Photos coming soon

2023 Lexus IS

350 F Sport RWD

35,259 miles

$43,247

Fair Deal
Store transfer to Myrtle Beach, SC
657 mi away • Price includes $249 shipping Price includes $249 shipping
Year:
2023
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
35,259
Stock number:
28011063
VIN:
JTHGZ1B20P5061529

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

42,278 miles

$36,755

Great Deal
Summerville, SC
86 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
42,278
Stock number:
K4146
VIN:
JTHGZ1B22N5049962

Preparing for a close up...

Photos coming soon

2023 Lexus IS

350 F Sport RWD

16,542 miles

$43,300

Good Deal
Summerville, SC
86 mi away
Year:
2023
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
16,542
Stock number:
AD1175
VIN:
JTHGZ1B29P5070939

Preparing for a close up...

Photos coming soon

2022 Lexus IS

350 F Sport RWD

42,278 miles

$36,755

Great Deal
Summerville, SC
86 mi away
Year:
2022
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
42,278
Stock number:
K4146
VIN:
JTHGZ1B22N5049962

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus IS
  4. / 2022
  5. / South Carolina
  6. / Myrtle Beach
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus IS

Picture of 2022 Lexus IS ## Summary - With 782 currently listed for sale on CarGurus and an **average price of $37,621.00**, 28.1% of 2022 Lexus IS models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Lexus IS 5 / 5 stars. - **81.3% of 2022 IS models on CarGurus are accident free**. - The 2022 Lexus IS lineup returns with a handful of minor updates and a significant improvement in performance with the debut of the powerful IS 500 F Sport Performance variant, featuring a 5.0-liter V8 engine that offers exhilarating driving dynamics. ## Why it stands out The 2022 Lexus IS distinguishes itself with its luxurious feel, quiet ride, and reliable performance, making it a significant choice among compact luxury sports sedans. The introduction of the IS 500 F Sport Performance variant introduces a normally aspirated 5.0-liter V8 engine producing 472 horsepower and 395 lb-ft of torque, delivering sporty yet comfortable driving dynamics. This year’s model retains the high-quality interior design and the user-friendly touchscreen infotainment system that enhances the driving experience. While some reviewers noted that the fuel economy could be improved, the overall excitement the IS provides, especially with its outstanding technology and safety features, makes it a compelling option for buyers seeking both performance and luxury. ## Other model years to consider - **[2023 Lexus IS](https://www.cargurus.com/Cars/l-Used-2023-Lexus-IS-c32540)** - Average price: $40,654.00 - Good/great deal percentage: 27.2% - User rating: 4.86 / 5 - Total listings: 852 - **[2024 Lexus IS](https://www.cargurus.com/Cars/l-Used-2024-Lexus-IS-c33195)** - Average price: $41,837.00 - Good/great deal percentage: 27.2% - User rating: 5 / 5 - Total listings: 827 - **[2021 Lexus IS](https://www.cargurus.com/Cars/l-Used-2021-Lexus-IS-c30887)** - Average price: $33,782.00 - Good/great deal percentage: 28.2% - User rating: 4.56 / 5 - Total listings: 468 This analysis is based on CarGurus' proprietary market data from February 23, 2026, CarGurus experts' opinions, and generative AI.

5 Overall rating

(8 reviews)
John S
5.0
Reviewed a 2022 Lexus IS on Sep 26, 2023

Wonderful vehicle very reliable. Basically its a bullet proof engine as long as you maintain the maintenance. Its stylish and resale value is strong.

Anonymous
5.0
Reviewed a 2022 Lexus IS on Nov 09, 2023

Can’t get over the quietness of the car city/highway driving. Purchased the Lexus brand for quality and reliability after problems with my previous car. So let’s hope I experience a positive experience from now on

Donald B
5.0
Reviewed a 2022 Lexus IS on Aug 04, 2022

I like the fact that it’s AWD V 6 engine plus my new vehicle has a smooth ride great on gas which is a plus over all it’s a beautiful car

Jose G
5.0
Reviewed a 2022 Lexus 350 F Sport RWD on Sep 13, 2024

A super nice vehicle ,has a beautiful sporty look

Luisa F
5.0
Reviewed a 2022 Lexus IS on Feb 22, 2024

this is my first Lexus. I love it. Smooth ride and handling.

2022 Lexus IS FAQs

How much does the 2022 Lexus IS cost in Myrtle Beach, SC?

The average 2022 Lexus IS costs about $37,737.98. The average price has decreased by -1.7% since last year. The 97 for sale near Myrtle Beach, SC on CarGurus, range from $25,520 to $69,158 in price.

Is the 2022 Lexus IS a good car?

CarGurus experts gave the 2022 Lexus IS an overall rating of 8.2/10 and 2022 Lexus IS owners have rated the vehicle a 5/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus IS vehicles in Myrtle Beach, SC have no reported accidents or damage?

81 out of 97 for sale near Myrtle Beach, SC have no reported accidents or damage.

Is the 2022 Lexus IS safe?

CarGurus experts gave the 2022 Lexus IS a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus IS?

Depending on the engine and options, the 2022 Lexus IS gets between 20 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus IS in Myrtle Beach SC

  • 2024 Lexus IS

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  • 2021 Lexus IS

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  • Lexus IS 300 RWD

  • Lexus IS 350 F Sport RWD

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  • Lexus IS 350 F Sport AWD

  • Lexus IS 500 F Sport Performance Premium RWD

  • Lexus IS 500 F Sport Performance RWD

  • Lexus IS 500 F Sport Launch Edition RWD

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