Used 2022 Lexus IS for Sale near Mississippi
90 results
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 14,896
- Stock #:
- JH071447
- VIN:
- JTHGZ1B24P5071447
Sponsored by Porsche Jackson
2023 Lexus IS
350 F SPORT RWD
14,896 mi
$44,325
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Matador Red Mica 3r1
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel W/ Black Metallic Trim Eb41
- Transmission:
- 8-Speed Automatic
- Mileage:
- 21,451
- Stock #:
- 24967
- VIN:
- JTHCA1D27P5124967
Sponsored Listing
2023 Lexus IS
300 RWD
21,451 mi
$37,900
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- CREAM
- Transmission:
- Automatic
- Mileage:
- 32,647
- Stock #:
- 28137288
- VIN:
- JTHGZ1B26M5039515
2021 Lexus IS
350 F Sport RWD
32,647 mi
$39,197
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White
- Transmission:
- 8-Speed Automatic
- Mileage:
- 56,338
- Stock #:
- C7382
- VIN:
- JTHGZ1B22N5054272
-$854
2022 Lexus IS
350 F Sport RWD
56,338 mi
$38,139
$37,285
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,353
- Stock #:
- P052005
- VIN:
- JTHGZ1B22N5052005
2022 Lexus IS
350 F Sport RWD
49,353 mi
$37,900
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,078
- Stock #:
- 28517958
- VIN:
- JTHGZ1B29N5053197
2022 Lexus IS
350 F Sport RWD
30,078 mi
$37,447
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 14,896
- Stock #:
- JH071447
- VIN:
- JTHGZ1B24P5071447
2023 Lexus IS
350 F SPORT RWD
14,896 mi
$44,325
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White
- Transmission:
- Automatic
- Mileage:
- 25,937
- Stock #:
- 29004997
- VIN:
- JTHGZ1B28N5056530
2022 Lexus IS
350 F Sport RWD
25,937 mi
$42,197
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 47,225
- Stock #:
- 119610
- VIN:
- JTHAA1D21N5119610
2022 Lexus IS
300 RWD
47,225 mi
$31,610
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gold
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 104,904
- Stock #:
- MAS-113637
- VIN:
- JTHAA1D24M5113637
2021 Lexus IS
300 RWD
104,904 mi
$26,012
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Matador Red Mica 3r1
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel W/ Black Metallic Trim Eb41
- Transmission:
- 8-Speed Automatic
- Mileage:
- 21,451
- Stock #:
- 24967
- VIN:
- JTHCA1D27P5124967
2023 Lexus IS
300 RWD
21,451 mi
$37,900
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 31,921
- Stock #:
- 123057AA
- VIN:
- JTHDA1D21P5123057
2023 Lexus IS
300 RWD
31,921 mi
$37,313
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,263
- Stock #:
- 061379
- VIN:
- JTHGZ1B27P5061379
2023 Lexus IS
350 F SPORT RWD
46,263 mi
$43,332
CarGurus Analysis:
2022 Lexus IS
With 983 currently listed for sale and an average price of $38,352.00, 33.9% of 2022 Lexus IS cars for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus IS 5 / 5 stars.
82.5% of 2022 Lexus IS models on CarGurus are accident-free.
The 2022 Lexus IS combines a luxurious feel with a quiet ride and powerful V6 engine performance, appealing to driving enthusiasts while providing all-wheel drive capability.
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 62,311
- Stock #:
- 112903
- VIN:
- JTHAA1D25M5112903
2021 Lexus IS
300 RWD
62,311 mi
$31,510
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 472 hp 5L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 51,944
- Stock #:
- 002805
- VIN:
- JTHAP1D2XP5002805
2023 Lexus IS
500 F SPORT Performance Premium RWD
51,944 mi
$55,506
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- ATOMIC SILVER
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 30,089
- Stock #:
- 118239
- VIN:
- JTHAA1D24N5118239
2022 Lexus IS
300 RWD
30,089 mi
$34,048
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 15,395
- Stock #:
- 70022527
- VIN:
- JTHGZ1B27P5067456
2023 Lexus IS
350 F SPORT RWD
15,395 mi
$45,897
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 46,110
- Stock #:
- 28355098
- VIN:
- JTHGZ1B26M5038462
2021 Lexus IS
350 F Sport RWD
46,110 mi
$40,247
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 10,260
- Stock #:
- P061460
- VIN:
- JTHGZ1B21P5061460
-$1,000
2023 Lexus IS
350 F SPORT RWD
10,260 mi
$48,663
$47,663
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,744
- Stock #:
- B7235AA
- VIN:
- JTHGZ1B24N5054743
2022 Lexus IS
350 F Sport RWD
58,744 mi
$40,450
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 24,759
- Stock #:
- 70031018
- VIN:
- JTHDA1D21P5127190
2023 Lexus IS
300 RWD
24,759 mi
$37,897
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,137
- Stock #:
- F041084
- VIN:
- JTHGZ1B24M5041084
2021 Lexus IS
350 F Sport RWD
96,137 mi
$34,872
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White
- Transmission:
- Automatic
- Mileage:
- 19,618
- Stock #:
- 70046802
- VIN:
- JTHGZ1E26N5026129
2022 Lexus IS
350 F SPORT AWD
19,618 mi
$45,997
CarGurus Analysis: 2022 Lexus IS
overall
Summary
With 983 currently listed for sale and an average price of $38,352.00, 33.9% of 2022 Lexus IS cars for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus IS 5 / 5 stars.
82.5% of 2022 Lexus IS models on CarGurus are accident-free.
The 2022 Lexus IS combines a luxurious feel with a quiet ride and powerful V6 engine performance, appealing to driving enthusiasts while providing all-wheel drive capability.
Why it stands out
The 2022 Lexus IS stands out in the compact luxury sedan segment for its exceptional combination of performance, comfort, and technology. With nearly all rivals being less expensive, the IS offers an exhilarating driving experience, particularly with the introduction of the 5.0-liter V8 in the IS 500 F Sport Performance model, delivering 472 horsepower. This model is praised not only for its raw power but also for its refined handling dynamics, making it perfect for both daily commutes and spirited drives. Expert reviews highlight features like a user-friendly infotainment system with a touchscreen interface and advanced safety features provided by Lexus Safety System+ 2.5, which contributes to its overall appeal. However, some limitations such as cargo space and noise levels have been noted, though they are often overshadowed by the car's engaging driving experience and luxurious interior.
Other model years to consider
- Average price: $44,144.00
- Good/great deal percentage: 36.3%
- Total listings: 1,337
- Average price: $42,156.00
- Good/great deal percentage: 34.7%
- User rating: 4.8 / 5
- Total listings: 1,219
- Average price: $17,714.00
- Good/great deal percentage: 31.8%
- User rating: 4.56 / 5
- Total listings: 762
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles
The Most Reliable Luxury Cars of 2026
Luxury cars give you the best of most things but which are the most reliable luxury cars you can buy? Our guide has all the details.
2026 Lexus IS Pricing, Specs, and Release Date
The Lexus IS gets a refresh for 2026 with new styling touches, a bigger infotainment display and instrument cluster, and retuned driving dynamics.
Lexus IS Buying Guide: Cost, Reliability, and the Best Years to Buy
Discover the ultimate buying guide for purchasing a used Lexus IS covering each generation since 2001. Whether you're a first-time buyer or a Lexus enthusiast, this comprehensive overview will help you research your next pre-owned Lexus IS.
5.0 Overall rating
Filter by rating
Jessica C
Reviewed a 2022 Lexus IS on Mar 6, 2025
Absolutely love this car. Quiet, luxurious and classy. Has enough power. Only downfall is gas mileage.
Luis D
Reviewed a 2022 Lexus 350 F Sport RWD on Sep 22, 2025
The car is amazing would highly recommend. This car drives like a dream.
John S
Reviewed a 2022 Lexus IS on Sep 27, 2023
Wonderful vehicle very reliable. Basically its a bullet proof engine as long as you maintain the maintenance. Its stylish and resale value is strong.
Anonymous
Reviewed a 2022 Lexus IS on Nov 10, 2023
Can’t get over the quietness of the car city/highway driving. Purchased the Lexus brand for quality and reliability after problems with my previous car. So let’s hope I experience a positive experience from now on
2022 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 500 F Sport Launch Edition RWD | $67,400 |
| 500 F Sport Performance Premium RWD | $61,350 |
| 300 AWD | $41,125 |
| 350 F SPORT AWD | $45,550 |
| 300 RWD | $39,125 |
| 350 F Sport RWD | $43,550 |
2022 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus IS prices has changed over time.
See more price trends
