Used 2021 Lexus IS for Sale near Mississippi

How much does the 2021 Lexus IS cost?

Prices have softened 1.28% compared to this time last year, making it a favorable time to shop this model year.

There are 512 listings available, which gives you a solid pool to compare prices and equipment.

Is the 2021 Lexus IS a good car?

Yes — the 2021 Lexus IS earns a 4.6/5 user rating and a 7.3/10 expert rating. The model scores 8/10 across Look and feel and Cost effectiveness.

Owners repeatedly praise the stylish design, sporty feel, handling, and luxurious feel, and many also point to its value for money. The review summary also highlights strong safety features, which helps reinforce its appeal for buyers who want a compact luxury sedan with personality.

The trade-offs are clear: the base engine is underwhelming, the transmission can be irritating, and the technology feels outdated. That makes it a better fit if you care more about driving character and design than the latest cabin tech.

The 2021 IS is aimed at enthusiast drivers and luxury buyers who might otherwise be looking at German rivals, and that sharper personality is a big part of its appeal. With 35.9% of listings marked as good or great deals, the market still offers some attractive opportunities.

Is the 2021 Lexus IS reliable?

Owners rate it 4.6/5, a strong signal of long-term satisfaction.

The owner feedback points to a dependable, trouble-free ownership experience, with many drivers emphasizing the car’s quality and the confidence they have in it over time. The expert evaluation also reinforces that impression by noting Lexus’ reputation for quality and reliability, along with the brand’s strong build quality and thoughtful engineering.

The standard maintenance and ownership support features add some reassurance, including service alerts and connected safety services. For used buyers, the main long-term risk is less about core durability and more about whether a specific car has been maintained well and equipped with the features you want.

What should I look for when buying a used 2021 Lexus IS?

At 67.4% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if the car has had prior damage or multiple owners. Focus on condition, maintenance records, and whether the equipment on the car matches what you expect from the trim and options. If you’re comparing several listings, the cleanest history and best-documented service record should carry extra weight.

Key things to evaluate:

• Trim level: The IS 300 RWD starts at $39,000, the IS 300 AWD starts at $41,000, the IS 350 RWD F Sport starts at $42,900, and the IS 350 AWD F Sport starts at $44,900. The F Sport models add a more aggressive setup and are the better fit if you want the sportiest character, while the base cars are the value-oriented entry points.
• Powertrain: The IS 300 RWD uses a 2.0-liter turbocharged inline-four with 241 horsepower and 258 pound-feet of torque. The IS 300 AWD uses a naturally aspirated 3.5-liter V6 with 260 hp, while the IS 350 models use the same V6 tuned to 311 hp and 280 lb-ft. RWD models use an eight-speed automatic, and AWD models use a six-speed automatic.
• Safety package: Lexus Safety System+ 2.5 is standard and includes pre-collision braking with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. It also includes blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
• Infotainment: The infotainment system uses a touchscreen and supports both Android Auto and Apple CarPlay. Lexus Enform Remote is free for three years, Service Connect comes with a 10-year complimentary subscription, and WiFi and navigation-related services are tied to trial periods and subscriptions.
• Fuel efficiency: The IS 300 RWD is rated at 21 mpg city and 31 mpg highway, the IS 300 AWD at 19 mpg city and 26 mpg highway, the IS 350 RWD at 20 mpg city and 28 mpg highway, and the IS 350 AWD at 19 mpg city and 26 mpg highway.

Which 2021 Lexus IS trim should I buy?

The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.

Here's the short version:

• IS 300 RWD: This is the entry point and the best-value choice if you want the lowest starting price and the standard rear-wheel-drive setup. It gives you the core IS experience without stepping up to the pricier V6 models.
• IS 300 AWD: Choose this if you want the added traction of all-wheel drive and the naturally aspirated V6. It costs more than the RWD version, but it adds a different character and may suit you if you prioritize all-weather confidence.
• IS 350 RWD F Sport: This is the strongest pick if you want the most engaging balance of performance and value. It brings the more powerful V6 and the F Sport treatment, making it the best-value trim for shoppers who care most about driving feel.
• IS 350 AWD F Sport: Pick this if you want the top-end version with all-wheel drive and the strongest output in the lineup. It makes the most sense if you want maximum performance-oriented equipment and don’t mind paying more for it.

Lexus Safety System+ 2.5 is standard across the lineup, so you get the same core safety suite regardless of trim.

Is now a good time to buy a used 2021 Lexus IS?

This looks like a moderate, selective buyer’s market, so you can shop carefully and still find worthwhile listings.

• Deal availability: 35.9% of listings are priced as good or great deals.
• Inventory: There are 512 listings available.
• Price trend: Prices have softened 1.28% compared with last year.
• Clean inventory: 67.4% of listings are accident-free.

If you find a listing below $33,075, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2021 Lexus IS's resale value?

The current average of $33,958 sits slightly below last year's $34,397.

That softer pricing suggests the model has already absorbed some depreciation, which can help future sellers if they buy at the right price. If you shop carefully now, you may have a better chance of limiting your own depreciation exposure later. The current range also gives you a useful benchmark for judging whether a listing is priced fairly.

Vehicles with strong owner satisfaction ratings, like this model year's 4.6/5, tend to retain buyer demand, which supports resale value over time.

Is the 2021 Lexus IS safe?

The 2021 Lexus IS hasn’t yet been rated for crashworthiness by IIHS or NHTSA.

It earns a 7/10 safety score from our experts.

Lexus Safety System+ 2.5 is standard, and it includes pre-collision braking with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. It also includes blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect with SOS emergency assistance, roadside assistance, automatic collision notification, and stolen vehicle notification.

Should I buy a 2021 Lexus IS or consider a different year?

If you're weighing the 2021 against nearby model years, here's how to think about it:

Choose the 2021 if:

• 35.9% of listings are priced as good or great deals.
• At 67.4% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices have softened 1.28% compared with last year.
• Owners rate it 4.6/5 — a strong satisfaction signal.
• The 2021 model year brings the fourth-generation redesign and the Lexus Driving Signature focus on sharper handling.

Consider the 2022 if:

• At $36,703, the 2022 costs more than the current year's $33,958 average.
• It adds the IS 500 F Sport Performance with a V8 and stronger performance.

The bottom line: If you want the better value and are focused on the redesigned 2021 car’s styling and handling, this year makes sense. If you’re willing to pay more for a major performance upgrade, the 2022 is the stronger choice.

How does the 2021 Lexus IS compare to the 2021 BMW 3 Series?

Expert Pros & Cons (per CarGurus review team)

2021 Lexus IS:

• Pros: Stylish design, Multiple powertrain options, Great handling.
• Cons: Underwhelming base engine, Irritating transmission, Outdated technology.

2021 BMW 3 Series:

• Pros: Multiple body styles, Great handling, Impressive technology.
• Cons: Advanced safety features are not standard.

Our experts score the 2021 Lexus IS 7.3/10 and the 2021 BMW 3 Series 6.8/10. The Lexus stands out for its styling and handling, while the BMW counters with more impressive technology and multiple body styles. The Lexus also has a weaker base engine and older-feeling tech, whereas the BMW’s safety equipment is less comprehensive as standard.

Read our full side-by-side expert comparison here.

These recommendations are based on CarGurus' proprietary market data from November 10, 2026, CarGurus experts' opinions, and generative AI.