Used 2022 Lexus IS for Sale near Indiana
82 results
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White
- Transmission:
- 6-Speed Automatic
- Mileage:
- 61,017
- Stock #:
- T26H5775B
- VIN:
- JTHGZ1E21P5031953
Sponsored by Great Lakes Honda of Fishers
2023 Lexus IS
350 F SPORT AWD
61,017 mi
$39,193
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,137
- Stock #:
- F041084
- VIN:
- JTHGZ1B24M5041084
Sponsored Listing
2021 Lexus IS
350 F Sport RWD
96,137 mi
$34,151
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,317
- Stock #:
- STK058348
- VIN:
- JTHGZ1B27N5058348
Sponsored Listing
2022 Lexus IS
350 F Sport RWD
49,317 mi
$39,879
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 26,692
- Stock #:
- 70071664
- VIN:
- JTHDA1D29N5118086
2022 Lexus IS
300 RWD
26,692 mi
$35,997
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 28,485
- Stock #:
- F14079B
- VIN:
- JTHGZ1B24P5064885
-$1,300
2023 Lexus IS
350 F SPORT RWD
28,485 mi
$44,167
$42,867
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White
- Transmission:
- Automatic
- Mileage:
- 48,486
- Stock #:
- 28932389
- VIN:
- JTHGZ1B27N5050914
2022 Lexus IS
350 F Sport RWD
48,486 mi
$40,897
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 18,625
- Stock #:
- 883869
- VIN:
- JTHGZ1E26P5030555
2023 Lexus IS
350 F SPORT AWD
18,625 mi
$46,383
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 45,205
- Stock #:
- 70068972
- VIN:
- JTHC81F2XM5046382
2021 Lexus IS
300 AWD
45,205 mi
$35,247
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 472 hp 5L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 81,152
- Stock #:
- 28283264
- VIN:
- JTHUP1D28N5001128
2022 Lexus IS
500 F Sport Launch Edition RWD
81,152 mi
$47,998
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Carmel W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 99,642
- Stock #:
- 3024205
- VIN:
- JTHD81F27N5049066
2022 Lexus IS
300 AWD
99,642 mi
$30,430
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 91,865
- Stock #:
- 116601-CMAX
- VIN:
- JTHCA1D28M5116601
2021 Lexus IS
300 RWD
91,865 mi
$27,702
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 31,921
- Stock #:
- 123057AA
- VIN:
- JTHDA1D21P5123057
2023 Lexus IS
300 RWD
31,921 mi
$38,078
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 472 hp 5L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 51,944
- Stock #:
- 002805
- VIN:
- JTHAP1D2XP5002805
2023 Lexus IS
500 F SPORT Performance Premium RWD
51,944 mi
$56,014
CarGurus Analysis:
2022 Lexus IS
With 983 currently listed for sale and an average price of $38,352.00, 33.9% of 2022 Lexus IS cars for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus IS 5 / 5 stars.
82.5% of 2022 Lexus IS models on CarGurus are accident-free.
The 2022 Lexus IS combines a luxurious feel with a quiet ride and powerful V6 engine performance, appealing to driving enthusiasts while providing all-wheel drive capability.
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 74,851
- Stock #:
- 062761
- VIN:
- JTHGZ1B29P5062761
2023 Lexus IS
350 F SPORT RWD
74,851 mi
$41,173
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 16,821
- Stock #:
- 128275
- VIN:
- JTHDA1D23P5128275
2023 Lexus IS
300 RWD
16,821 mi
$38,102
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,263
- Stock #:
- 061379
- VIN:
- JTHGZ1B27P5061379
2023 Lexus IS
350 F SPORT RWD
46,263 mi
$43,326
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 10,260
- Stock #:
- P061460
- VIN:
- JTHGZ1B21P5061460
2023 Lexus IS
350 F SPORT RWD
10,260 mi
$48,542
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,137
- Stock #:
- F041084
- VIN:
- JTHGZ1B24M5041084
2021 Lexus IS
350 F Sport RWD
96,137 mi
$34,151
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 17,718
- Stock #:
- 069446
- VIN:
- JTHGZ1B23P5069446
2023 Lexus IS
350 F SPORT RWD
17,718 mi
$46,157
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 106,906
- Stock #:
- 020563
- VIN:
- JTHGZ1E25M5020563
2021 Lexus IS
350 F Sport AWD
106,906 mi
$30,508
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White
- Transmission:
- 6-Speed Automatic
- Mileage:
- 61,017
- Stock #:
- T26H5775B
- VIN:
- JTHGZ1E21P5031953
2023 Lexus IS
350 F SPORT AWD
61,017 mi
$39,193
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,317
- Stock #:
- STK058348
- VIN:
- JTHGZ1B27N5058348
2022 Lexus IS
350 F Sport RWD
49,317 mi
$39,879
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 53,893
- Stock #:
- K029277
- VIN:
- JTHGZ1E2XP5029277
-$1,001
Sponsored Listing
2023 Lexus IS
350 F SPORT AWD
53,893 mi
$42,531
$41,530
CarGurus Analysis: 2022 Lexus IS
overall
Summary
With 983 currently listed for sale and an average price of $38,352.00, 33.9% of 2022 Lexus IS cars for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus IS 5 / 5 stars.
82.5% of 2022 Lexus IS models on CarGurus are accident-free.
The 2022 Lexus IS combines a luxurious feel with a quiet ride and powerful V6 engine performance, appealing to driving enthusiasts while providing all-wheel drive capability.
Why it stands out
The 2022 Lexus IS stands out in the compact luxury sedan segment for its exceptional combination of performance, comfort, and technology. With nearly all rivals being less expensive, the IS offers an exhilarating driving experience, particularly with the introduction of the 5.0-liter V8 in the IS 500 F Sport Performance model, delivering 472 horsepower. This model is praised not only for its raw power but also for its refined handling dynamics, making it perfect for both daily commutes and spirited drives. Expert reviews highlight features like a user-friendly infotainment system with a touchscreen interface and advanced safety features provided by Lexus Safety System+ 2.5, which contributes to its overall appeal. However, some limitations such as cargo space and noise levels have been noted, though they are often overshadowed by the car's engaging driving experience and luxurious interior.
Other model years to consider
- Average price: $44,144.00
- Good/great deal percentage: 36.3%
- Total listings: 1,337
- Average price: $42,156.00
- Good/great deal percentage: 34.7%
- User rating: 4.8 / 5
- Total listings: 1,219
- Average price: $17,714.00
- Good/great deal percentage: 31.8%
- User rating: 4.56 / 5
- Total listings: 762
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
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The Lexus IS gets a refresh for 2026 with new styling touches, a bigger infotainment display and instrument cluster, and retuned driving dynamics.
Lexus IS Buying Guide: Cost, Reliability, and the Best Years to Buy
Discover the ultimate buying guide for purchasing a used Lexus IS covering each generation since 2001. Whether you're a first-time buyer or a Lexus enthusiast, this comprehensive overview will help you research your next pre-owned Lexus IS.
5.0 Overall rating
Filter by rating
Jessica C
Reviewed a 2022 Lexus IS on Mar 6, 2025
Absolutely love this car. Quiet, luxurious and classy. Has enough power. Only downfall is gas mileage.
Luis D
Reviewed a 2022 Lexus 350 F Sport RWD on Sep 22, 2025
The car is amazing would highly recommend. This car drives like a dream.
John S
Reviewed a 2022 Lexus IS on Sep 27, 2023
Wonderful vehicle very reliable. Basically its a bullet proof engine as long as you maintain the maintenance. Its stylish and resale value is strong.
Anonymous
Reviewed a 2022 Lexus IS on Nov 10, 2023
Can’t get over the quietness of the car city/highway driving. Purchased the Lexus brand for quality and reliability after problems with my previous car. So let’s hope I experience a positive experience from now on
2022 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 500 F Sport Launch Edition RWD | $67,400 |
| 500 F Sport Performance Premium RWD | $61,350 |
| 300 AWD | $41,125 |
| 350 F SPORT AWD | $45,550 |
| 300 RWD | $39,125 |
| 350 F Sport RWD | $43,550 |
2022 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus IS prices has changed over time.
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