Used 2021 Toyota Sienna for Sale near Rochester, NY
88 results
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Predawn Gray Mica
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 31,021
- Stock #:
- B260518242T1
- VIN:
- 5TDYRKEC9MS032911


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2021 Toyota Sienna
XLE 7-Passenger FWD
31,021 mi
$40,165
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- BLIZZARD PEARL WHITE
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (GREY LEATHER)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 112,000
- Stock #:
- 14137
- VIN:
- 5TDYSKFC6MS017611

2021 Toyota Sienna
XLE 7-Passenger AWD
112,000 mi
$30,191
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 68,312
- Stock #:
- 082639
- VIN:
- 5TDZZ3DC2LS082639

2020 Toyota Sienna
L 7-Passenger FWD
68,312 mi
$23,506
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Midnight Black Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 60,683
- Stock #:
- b251677
- VIN:
- 5TDDZ3DC9LS251677

2020 Toyota Sienna
Limited Premium 7-Passenger AWD
60,683 mi
$36,769
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 108,071
- Stock #:
- 28813654
- VIN:
- 5TDZRKEC4MS039687

2021 Toyota Sienna
Limited 7-Passenger FWD
108,071 mi
$31,347
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 152,224
- Stock #:
- J6319
- VIN:
- 5TDKRKEC0MS064748

-$800
2021 Toyota Sienna
LE 8-Passenger FWD
152,224 mi
$25,192
$24,392
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Midnight Black Metallic
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 67,941
- Stock #:
- C011011
- VIN:
- 5TDGSKFC2MS011011

2021 Toyota Sienna
LE 8-Passenger AWD
67,941 mi
$36,582
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 37,508
- Stock #:
- 251491
- VIN:
- 5TDJZ3DC2LS251491

2020 Toyota Sienna
LE 7-Passenger AWD
37,508 mi
$31,188
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red (Ruby Flare Pearl)
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Chateau
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 62,217
- Stock #:
- 266860A
- VIN:
- 5TDJSKFC0MS030968

2021 Toyota Sienna
XLE 7-Passenger AWD
62,217 mi
$36,248
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Cement
- Transmission:
- 8-Speed Automatic
- Mileage:
- 55,000
- Stock #:
- 27455
- VIN:
- 5TDDZ3DC8LS234580

2020 Toyota Sienna
XLE 7-Passenger AWD
55,000 mi
$32,377
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 25,461
- Stock #:
- 082832
- VIN:
- 5TDZZ3DC7LS082832

2020 Toyota Sienna
L 7-Passenger FWD
25,461 mi
$30,845
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 70,131
- Stock #:
- 70075641
- VIN:
- 5TDYRKEC3MS038929

2021 Toyota Sienna
XLE 7-Passenger FWD
70,131 mi
$38,147
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Predawn Gray Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,835
- Stock #:
- 46629
- VIN:
- 5TDZZ3DC5LS045262

2020 Toyota Sienna
L 7-Passenger FWD
96,835 mi
$21,117
CarGurus Analysis:
2021 Toyota Sienna
With 1,116 currently listed for sale and an average price of $35,346.00, 29.7% of 2021 Toyota Sierras for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.33 / 5 stars.
73.1% of 2021 Sienna models on CarGurus are accident free.
The 2021 Toyota Sienna features a new hybrid powertrain, providing a spacious interior, excellent gas mileage, and smooth handling, along with various family-friendly features.
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (Beige)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 39,936
- Stock #:
- S11431Z
- VIN:
- 5TDDRKEC6MS019547

2021 Toyota Sienna
XSE 7-Passenger FWD
39,936 mi
$39,674
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 118,776
- Stock #:
- J6318
- VIN:
- 5TDKRKEC3NS115743

2022 Toyota Sienna
LE 8-Passenger FWD
118,776 mi
$29,056
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Predawn Gray Mica
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Chateau
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 83,981
- Stock #:
- 16612
- VIN:
- 5TDYSKFC3MS008574

2021 Toyota Sienna
XLE 7-Passenger AWD
83,981 mi
$35,052
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 121,657
- Stock #:
- 035675
- VIN:
- 5TDYZ3DC8LS035675

2020 Toyota Sienna
XLE Premium 8-Passenger FWD
121,657 mi
$21,611
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 83,321
- Stock #:
- 063571
- VIN:
- 5TDZZ3DC9LS063571

2020 Toyota Sienna
L 7-Passenger FWD
83,321 mi
$24,936
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 78,995
- Stock #:
- 28785142
- VIN:
- 5TDYZ3DC6LS073437

2020 Toyota Sienna
XLE 7-Passenger FWD with Auto-Access Seat
78,995 mi
$32,647
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 71,993
- Stock #:
- 28949713
- VIN:
- 5TDYRKEC8MS006414

2021 Toyota Sienna
XLE 7-Passenger FWD
71,993 mi
$37,497
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- White (Blizzard Pearl)
- Fuel type:
- Gasoline
- Interior color:
- Ash
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,207
- Stock #:
- 62278
- VIN:
- 5TDKZ3DC0LS070765

2020 Toyota Sienna
58,207 mi
$29,882
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Super White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 143,421
- Stock #:
- 4554
- VIN:
- 5TDZZ3DC7LS034442

2020 Toyota Sienna
L 7-Passenger FWD
143,421 mi
$18,931
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Mileage:
- 122,406
- Stock #:
- 228940
- VIN:
- 5TDDZ3DC4LS228940

2020 Toyota Sienna
XLE 7-Passenger AWD
122,406 mi
$26,276
CarGurus Analysis: 2021 Toyota Sienna
overall

Summary
With 1,116 currently listed for sale and an average price of $35,346.00, 29.7% of 2021 Toyota Sierras for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.33 / 5 stars.
73.1% of 2021 Sienna models on CarGurus are accident free.
The 2021 Toyota Sienna features a new hybrid powertrain, providing a spacious interior, excellent gas mileage, and smooth handling, along with various family-friendly features.
Why it stands out
The 2021 Toyota Sienna sets itself apart as a hybrid minivan that combines functionality with modern technology. For the first time, it comes exclusively with a hybrid powertrain that delivers an impressive 36 mpg, achieving both power and efficiency. Its redesign enhances both appearance and utility, showcasing a more SUV-like silhouette while offering ample cabin space—featuring best-in-class cargo capacity. Improvements in handling and comfort stem from the new TNGA platform, which reduces body roll significantly. Moreover, the interior is equipped with a suite of technological features, including standard Apple CarPlay, Android Auto, and a large touchscreen. Families will appreciate the spaciousness and convenience features, such as sliding doors and a versatile second-row seating arrangement. However, some users note the lackluster audio system and interior material quality as areas for improvement. Overall, the 2021 Sienna caters to the needs of families looking for a practical yet stylish vehicle.
Other model years to consider
- Average price: $37,245.00
- Good/great deal percentage: 31.4%
- User rating: 4.75 / 5
- Total listings: 1,236
- Average price: $17,436.00
- Good/great deal percentage: 31.2%
- User rating: 5 / 5
- Total listings: 1,132
- Average price: $15,123.00
- Good/great deal percentage: 30.2%
- User rating: 4.88 / 5
- Total listings: 900
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
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4.4 Overall rating
Filter by rating
Anisa S
Reviewed a 2021 Toyota LE 8-Passenger AWD on Jan 25, 2023
Good cars and valuable for big family easy access
Anonymous
Reviewed a 2021 Toyota Sienna on Oct 12, 2021
Excellent gas mileage, very roomy, and stylish interior.
Sarin J
Reviewed a 2021 Toyota Sienna on May 11, 2021
HUD, Gas mileage, Radar cruise with lane trace assist etc. makes it a great vehicle for long road trips. Wish the BSM indicators appear on the HUD and have more options displayed on the HUD as well. Also the Android Auto\Apple Car Play navigation is not projected into HUD. Wish that was included as well.
Sarah M
Reviewed a 2021 Toyota Sienna on Dec 28, 2023
I love to drive. This car floats! It turns on a dime and has some power. All the room you’ll ever need, kids not required! This car is the only car I will ever buy again!
2021 Toyota Sienna Trims
| Trim type | MSRP |
|---|---|
| Platinum 7-Passenger AWD | $50,460 |
| LE 8-Passenger AWD | $36,460 |
| Limited 7-Passenger FWD | $46,700 |
| XSE 7-Passenger AWD | $42,760 |
| XSE 7-Passenger FWD | $42,000 |
| XLE 7-Passenger AWD | $41,750 |
| LE 8-Passenger FWD | $34,460 |
| XLE 7-Passenger FWD | $39,750 |
2021 Toyota Sienna Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Toyota Sienna prices has changed over time.
See more price trends