Used 2021 Toyota Sienna for Sale near Cleveland, OH
85 results
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- White (Blizzard Pearl)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Hickory
- Transmission:
- 8-Speed Automatic
- Mileage:
- 165,258
- Stock #:
- 6247T
- VIN:
- 5TDDZ3DC4LS238481

Sponsored Listing
2020 Toyota Sienna
XLE Premium 7-Passenger AWD
165,258 mi
$21,639
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Moonstone
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 64,072
- Stock #:
- PJJH9392
- VIN:
- 5TDGRKEC3MS049392

Sponsored Listing
2021 Toyota Sienna
XLE 8-Passenger FWD
64,072 mi
$33,398
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Cement
- Transmission:
- Automatic
- Mileage:
- 90,739
- Stock #:
- 25B01784C
- VIN:
- 5TDDZ3DC0LS250823

Sponsored Listing
2020 Toyota Sienna
XLE 7-Passenger AWD
90,739 mi
$29,189
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red (Ruby Flare Pearl)
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Chateau
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 62,217
- Stock #:
- 266860A
- VIN:
- 5TDJSKFC0MS030968

2021 Toyota Sienna
XLE 7-Passenger AWD
62,217 mi
$35,565
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Midnight Black Metallic
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 99,260
- Stock #:
- TT0409A
- VIN:
- 5TDZSKFCXMS023593

2021 Toyota Sienna
Limited 7-Passenger AWD
99,260 mi
$32,791
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Super White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Cement
- Transmission:
- 8-Speed Automatic
- Mileage:
- 121,441
- Stock #:
- 260105B
- VIN:
- 5TDDZ3DC9LS232398

2020 Toyota Sienna
Limited Premium 7-Passenger AWD
121,441 mi
$27,398
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Predawn Gray Mica
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 71,577
- Stock #:
- NKGB1718C
- VIN:
- 5TDKRKEC0MS013749

-$1,000
2021 Toyota Sienna
LE 8-Passenger FWD
71,577 mi
$31,348
$30,348
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- White (Blizzard Pearl)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Hickory
- Transmission:
- 8-Speed Automatic
- Mileage:
- 165,258
- Stock #:
- 6247T
- VIN:
- 5TDDZ3DC4LS238481

2020 Toyota Sienna
XLE Premium 7-Passenger AWD
165,258 mi
$21,639
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 97,387
- Stock #:
- 229984
- VIN:
- 5TDDZ3DC7LS229984

2020 Toyota Sienna
Limited 7-Passenger AWD
97,387 mi
$31,192
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Moonstone
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 64,072
- Stock #:
- PJJH9392
- VIN:
- 5TDGRKEC3MS049392

2021 Toyota Sienna
XLE 8-Passenger FWD
64,072 mi
$33,398
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 118,065
- Stock #:
- A704
- VIN:
- 5TDYZ3DC6LS064639

2020 Toyota Sienna
XLE 7-Passenger FWD with Auto-Access Seat
118,065 mi
$21,999
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Blueprint
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Moonstone/Grey Flannel)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 110,920
- Stock #:
- GO8267
- VIN:
- 5TDGSKFC6MS025249

2021 Toyota Sienna
XSE 7-Passenger AWD
110,920 mi
$31,588
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Cement
- Transmission:
- Automatic
- Mileage:
- 90,739
- Stock #:
- 25B01784C
- VIN:
- 5TDDZ3DC0LS250823

2020 Toyota Sienna
XLE 7-Passenger AWD
90,739 mi
$29,189
CarGurus Analysis:
2021 Toyota Sienna
With 84 currently listed for sale near Cleveland, OH and an average price of $32,701.00, 25.0% of 2021 Toyota Siennas for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.33 / 5 stars.
100.0% of 2021 Sienna models on CarGurus are accident free.
The 2021 Toyota Sienna features a new eco-friendly hybrid engine, offering excellent fuel efficiency of up to 36 mpg combined, and an impressively spacious interior.
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Super White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 143,421
- Stock #:
- 4554
- VIN:
- 5TDZZ3DC7LS034442

2020 Toyota Sienna
L 7-Passenger FWD
143,421 mi
$18,723
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 152,224
- Stock #:
- J6319
- VIN:
- 5TDKRKEC0MS064748

2021 Toyota Sienna
LE 8-Passenger FWD
152,224 mi
$24,089
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Sunset Bronze Mica
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 77,039
- VIN:
- 5TDZRKEC6MS042400

2021 Toyota Sienna
Limited 7-Passenger FWD
77,039 mi
$36,013
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 114,135
- Stock #:
- 12752
- VIN:
- 5TDDZ3DC7LS236076

2020 Toyota Sienna
XLE 7-Passenger AWD
114,135 mi
$25,681
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Midnight Black Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 60,683
- Stock #:
- b251677
- VIN:
- 5TDDZ3DC9LS251677

2020 Toyota Sienna
Limited Premium 7-Passenger AWD
60,683 mi
$35,459
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 118,776
- Stock #:
- J6318
- VIN:
- 5TDKRKEC3NS115743

2022 Toyota Sienna
LE 8-Passenger FWD
118,776 mi
$28,753
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 79,870
- Stock #:
- C25-0420A
- VIN:
- 5TDKSKFC4NS070783

2022 Toyota Sienna
LE 8-Passenger AWD
79,870 mi
$33,100
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (Beige)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 39,936
- Stock #:
- S11431Z
- VIN:
- 5TDDRKEC6MS019547

2021 Toyota Sienna
XSE 7-Passenger FWD
39,936 mi
$39,876
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Grey Flannel)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 96,112
- Stock #:
- FL8127
- VIN:
- 5TDXRKEC1NS103404

2022 Toyota Sienna
XSE 7-Passenger FWD
96,112 mi
$36,068
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red (Ruby Flare Pearl)
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Chateau
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 62,217
- Stock #:
- 266860A
- VIN:
- 5TDJSKFC0MS030968

Sponsored Listing
2021 Toyota Sienna
XLE 7-Passenger AWD
62,217 mi
$35,565
CarGurus Analysis: 2021 Toyota Sienna
overall

Summary
With 84 currently listed for sale near Cleveland, OH and an average price of $32,701.00, 25.0% of 2021 Toyota Siennas for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.33 / 5 stars.
100.0% of 2021 Sienna models on CarGurus are accident free.
The 2021 Toyota Sienna features a new eco-friendly hybrid engine, offering excellent fuel efficiency of up to 36 mpg combined, and an impressively spacious interior.
Why it stands out
The 2021 Toyota Sienna makes a significant mark in the minivan segment, distinguished by its shift to a solely hybrid powertrain. This not only enhances fuel efficiency—achieving 36 mpg combined for front-wheel-drive models—but also reduces emissions, appealing to eco-conscious families. Its spacious and well-designed interior provides comfort for passengers, making it ideal for long road trips. The second-row seating can slide to maximize both passenger space and cargo capacity, while the sophisticated technology features, including a 9-inch touchscreen with Apple CarPlay and Android Auto, keep everyone entertained. Despite minor criticisms regarding interior material quality and acceleration, the overall ride quality is smooth. Additionally, Toyota’s commitment to safety is evident with the inclusion of Toyota Safety Sense 2.0 across all trims, ensuring peace of mind for families.
Other model years to consider
- Average price: $9,995.00
- Good/great deal percentage: 14.1%
- User rating: 5 / 5
- Total listings: 99
- Average price: $27,516.00
- Good/great deal percentage: 27.5%
- User rating: 4.71 / 5
- Total listings: 91
- Average price: $20,173.00
- Good/great deal percentage: 17.8%
- User rating: 4.88 / 5
- Total listings: 90
This analysis is based on CarGurus' proprietary market data from June 23, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

The Best Minivans for Camping in 2026
Getting your crew and gear to the campsite comfortably doesn’t have to mean driving a gas-guzzling SUV. Many minivans offer useful innovations for camping while delivering very good fuel economy.

The Best Cars for Uber in 2026
Driving for Lyft or Uber can be a great business, but in addition to making sure your vehicle is eligible for ridesharing, you'll also want to choose a ride that blends low costs for you with satisfaction for your passengers. Here are CarGurus' recs for the best cars for rideshare drivers.

The Best Hybrid Vehicles of 2026
The automotive world is going electric, but for many people, a hybrid vehicle is still the best choice. Hybrids offer lower emissions without the stress of charging and range management, and they aren't much more expensive these days.
4.4 Overall rating
Filter by rating
Anisa S
Reviewed a 2021 Toyota LE 8-Passenger AWD on Jan 25, 2023
Good cars and valuable for big family easy access
Anonymous
Reviewed a 2021 Toyota Sienna on Oct 12, 2021
Excellent gas mileage, very roomy, and stylish interior.
Sarin J
Reviewed a 2021 Toyota Sienna on May 11, 2021
HUD, Gas mileage, Radar cruise with lane trace assist etc. makes it a great vehicle for long road trips. Wish the BSM indicators appear on the HUD and have more options displayed on the HUD as well. Also the Android Auto\Apple Car Play navigation is not projected into HUD. Wish that was included as well.
Sarah M
Reviewed a 2021 Toyota Sienna on Dec 28, 2023
I love to drive. This car floats! It turns on a dime and has some power. All the room you’ll ever need, kids not required! This car is the only car I will ever buy again!
2021 Toyota Sienna Trims
| Trim type | MSRP |
|---|---|
| Platinum 7-Passenger AWD | $50,460 |
| LE 8-Passenger AWD | $36,460 |
| Limited 7-Passenger FWD | $46,700 |
| XSE 7-Passenger AWD | $42,760 |
| XSE 7-Passenger FWD | $42,000 |
| XLE 7-Passenger AWD | $41,750 |
| LE 8-Passenger FWD | $34,460 |
| XLE 7-Passenger FWD | $39,750 |
2021 Toyota Sienna Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Toyota Sienna prices has changed over time.
See more price trends