Used 2021 Mercedes-Benz S-Class for Sale near Charlotte, NC
189 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 187 currently listed for sale near Charlotte, NC and an average price of $57,249.00, 41.7% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
81.8% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a luxurious interior equipped with advanced technology, a mild-hybrid system for better performance, and cutting-edge driver assistance features.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 187 currently listed for sale near Charlotte, NC and an average price of $57,249.00, 41.7% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
81.8% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a luxurious interior equipped with advanced technology, a mild-hybrid system for better performance, and cutting-edge driver assistance features.
Why it stands out
The 2021 Mercedes-Benz S-Class continues to uphold its reputation as a flagship luxury sedan, showcasing a perfect blend of comfort, power, and cutting-edge technology. It has been redesigned to enhance its luxurious feel and deliver an exhilarating driving experience through its powerful engine choices, including a 3.0-liter turbocharged inline-six and a 4.0-liter twin-turbo V8, both equipped with a mild-hybrid EQ Boost system for improved efficiency. The car's vibrant interior is adorned with high-quality materials and features a sophisticated infotainment system with a large touchscreen and a digital instrument cluster, designed for easy and intuitive use. With advancements like rear-wheel steering and an exceptional air suspension system, the S-Class offers a graceful yet dynamic ride. Although the price is on the higher end, potential buyers are attracted to the blend of performance, luxury, and innovation that the S-Class represents.
Other model years to consider
- Average price: $62,849.00
- Good/great deal percentage: 43.2%
- User rating: 4.5 / 5
- Total listings: 243
- Average price: $166,593.00
- Good/great deal percentage: 40.6%
- Accident-free percentage: 88.9%
- Total listings: 271
- Average price: $26,483.00
- Good/great deal percentage: 29.5%
- User rating: 4.95 / 5
- Total listings: 207
This analysis is based on CarGurus' proprietary market data from June 2, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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