Used 2021 Mercedes-Benz E-Class for Sale near Phoenix, AZ
113 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 110 currently listed for sale near Phoenix, AZ and an average price of $57,022.00, 40.9% of 2021 Mercedes-Benz E-Class vehicles for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
104.5% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a refined infotainment system, enhanced engine options, and a luxurious cabin design.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 110 currently listed for sale near Phoenix, AZ and an average price of $57,022.00, 40.9% of 2021 Mercedes-Benz E-Class vehicles for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
104.5% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a refined infotainment system, enhanced engine options, and a luxurious cabin design.
Why it stands out
The 2021 Mercedes-Benz E-Class stands out for its elegant design, impressive performance, and luxurious interior. This model is characterized by its hybrid powertrain options, including the electrified inline-six engines that provide both power and efficiency. The E-Class doesn’t compromise on comfort, with a beautifully appointed cabin that boasts high-quality materials and cutting-edge technology. According to expert test drives, it combines practicality with luxury, making it a versatile choice for those who value both speed and comfort. However, some buyers may find that the advanced safety features are not all standard, which could be a consideration for those prioritizing safety.
Other model years to consider
- Average price: $46,705.00
- Good/great deal percentage: 49.1%
- User rating: 5 / 5
- Total listings: 112
- Average price: $44,009.00
- Good/great deal percentage: 30.7%
- User rating: 5 / 5
- Total listings: 140
- Average price: $56,136.00
- Good/great deal percentage: 52.9%
- User rating: 5 / 5
- Total listings: 87
This analysis is based on CarGurus' proprietary market data from April 14, 2026, CarGurus experts' opinions, and generative AI.
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4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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