Used 2021 Mercedes-Benz E-Class for Sale near Boston, MA
126 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 118 currently listed for sale near Boston, MA and an average price of $33,464.00, 55.9% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
100.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a mid-cycle update that enhances the infotainment system, offers multiple body styles, and incorporates advanced safety features, making it one of the most desirable luxury sedans.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 118 currently listed for sale near Boston, MA and an average price of $33,464.00, 55.9% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
100.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a mid-cycle update that enhances the infotainment system, offers multiple body styles, and incorporates advanced safety features, making it one of the most desirable luxury sedans.
Why it stands out
The 2021 Mercedes-Benz E-Class is celebrated for its impressive blend of luxury, performance, and modern technology. This model stands out with its versatile powertrain options, including the switch to electrified inline-six engines, which provide a balance of performance and efficiency. The E-Class showcases a beautifully designed interior with luxurious materials, cutting-edge infotainment, and an extensive array of safety features. With an expert rating of 8.33/10, it has proven to be a practical choice for buyers seeking both comfort and style. Although it is noted for being on the higher end of the price spectrum, the E-Class remains a preferred option for those who appreciate refined driving experiences and top-tier technology.
Other model years to consider
- Average price: $26,101.00
- Good/great deal percentage: 45.9%
- User rating: 5 / 5
- Total listings: 170
- Average price: $42,612.00
- Good/great deal percentage: 53.6%
- User rating: 5 / 5
- Total listings: 151
- Average price: $24,936.00
- Good/great deal percentage: 46.4%
- User rating: 4.76 / 5
- Total listings: 263
This analysis is based on CarGurus' proprietary market data from June 9, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
Elvis E
Reviewed a 2021 Mercedes-Benz E 350 RWD on Apr 30, 2023
Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 53 Coupe 4MATIC | $76,250 |
| E 450 Cabriolet RWD | $71,950 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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