Used 2021 Mercedes-Benz E-Class for Sale near Boston, MA
156 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 157 currently listed for sale near Boston, MA and an average price of $38,391.00, 39.5% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
89.2% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features an updated infotainment system, refined engine options, and luxurious materials throughout its cabin.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 157 currently listed for sale near Boston, MA and an average price of $38,391.00, 39.5% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
89.2% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features an updated infotainment system, refined engine options, and luxurious materials throughout its cabin.
Why it stands out
The 2021 Mercedes-Benz E-Class remains a top choice for those seeking a blend of performance, luxury, and cutting-edge technology. With a line of stylish body types and multiple powertrain options, including an electrified inline-six, the E-Class provides a tailored driving experience to meet various preferences. The lavish interior boasts high-quality materials and advanced tech, including a fully digital instrument cluster and an intuitive infotainment system that enhances usability. Notably, safety features are prevalent, with a mix of standard and available driver-assistance technologies. While its price tag can escalate quickly with options, the E-Class justifies its cost with an impressive balance of comfort and driving dynamics, solidifying its status as a remarkable option in the luxury sedan market.
Other model years to consider
- Average price: $30,549.00
- Good/great deal percentage: 34.0%
- User rating: 5 / 5
- Total listings: 188
- Average price: $44,191.00
- Good/great deal percentage: 42.0%
- User rating: 5 / 5
- Total listings: 157
- Average price: $28,118.00
- Good/great deal percentage: 29.8%
- User rating: 4.76 / 5
- Total listings: 275
This analysis is based on CarGurus' proprietary market data from April 21, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
See more price trends
