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Used 2021 Lexus RX for Sale near San Antonio, TX

99 results
San Antonio, TX
2020 Lexus RX 350 FWD Red McCombs Ford

2020 Lexus RX

350 FWD

98,071 miles

$27,500

Fair Deal
San Antonio, TX
7 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
98,071
Stock number:
F52665A
VIN:
2T2HZMAA9LC158740

Sponsored

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

55,134 miles

$40,977

Good Deal
Certified Pre-Owned
San Antonio, TX
9 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
Automatic
Mileage:
55,134
Stock number:
DC67138B
VIN:
2T2YZMDA0NC312976

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

64,821 miles

$36,781

Good Deal
Certified Pre-Owned
San Antonio, TX
17 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
64,821
Stock number:
UDC241368
VIN:
2T2HZMAAXNC241368

Sponsored

2020 Lexus RX 350 AWD

2020 Lexus RX

350 AWD

77,412 miles

$29,987

Good Deal
Selma, TX
16 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Charcoal)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
77,412
Stock number:
GT260532A
VIN:
2T2HZMDA9LC249731

2020 Lexus RX 350 FWD

2020 Lexus RX

350 FWD

106,902 miles

$26,097

Great Deal
Store transfer to San Antonio, TX
268 mi away • Price includes $99 shipping Price includes $99 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
106,902
Stock number:
27746852
VIN:
2T2HZMAA7LC156808

2021 Lexus RX 350 F Sport AWD

2021 Lexus RX

350 F Sport AWD

49,846 miles

$38,597

Good Deal
Store transfer to San Antonio, TX
1,067 mi away • Price includes $599 shipping Price includes $599 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
49,846
Stock number:
28198194
VIN:
2T2SZMDA8MC263028

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

33,460 miles

$38,597

Good Deal
Store transfer to San Antonio, TX
1,015 mi away • Price includes $599 shipping Price includes $599 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
33,460
Stock number:
28280874
VIN:
2T2HZMAA5MC202928

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

58,072 miles

$37,998

Great Deal
Boerne, TX
26 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
58,072
Stock number:
251960A
VIN:
2T2YZMDA1NC312856

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

73,491 miles

$35,140

Fair Deal
San Antonio, TX
7 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
73,491
Stock number:
428224A
VIN:
2T2HZMAA1NC221025

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport Handling AWD

60,610 miles

$36,781

Great Deal
Certified Pre-Owned
San Antonio, TX
17 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Blue
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
60,610
Stock number:
UDC269515
VIN:
2T2YZMDA2MC269515

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

59,565 miles

$32,487

Good Deal
New Braunfels, TX
33 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (Tan)
Transmission:
Automatic
Mileage:
59,565
Stock number:
CMC189786
VIN:
2T2HZMAAXMC189786

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

52,897 miles

$34,598

Fair Deal
New Braunfels, TX
29 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Ash
Transmission:
8-Speed Automatic
Mileage:
52,897
Stock number:
215687B
VIN:
2T2HZMAA8MC215687

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

56,898 miles

$38,993

Good Deal
San Antonio, TX
12 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
56,898
Stock number:
NC348631
VIN:
2T2YZMDA3NC348631

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

64,821 miles

$36,781

Good Deal
Certified Pre-Owned
San Antonio, TX
17 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
64,821
Stock number:
UDC241368
VIN:
2T2HZMAAXNC241368

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

27,004 miles

$40,995

Good Deal
Certified Pre-Owned
San Antonio, TX
8 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
27,004
Stock number:
LC255064
VIN:
2T2AZMAA3NC255064

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

73,491 miles

$35,140

Fair Deal
San Antonio, TX
7 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
73,491
Stock number:
428224A
VIN:
2T2HZMAA1NC221025

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2021
  5. / Texas
  6. / San Antonio
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Lexus RX

Picture of 2021 Lexus RX

Summary

  • With 1,829 currently listed for sale on CarGurus and an average price of $35,773.40, 32.3% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2021 Lexus RX 4.7 / 5 stars and CarGurus experts gave it an 7.8 / 10.
  • 79% of 2021 RX models on CarGurus are accident free.
  • The 2021 Lexus RX combined luxurious comfort with reliability, featuring upgraded safety technology and a smooth ride, although it had some limitations in performance and technology usability.

Why it stands out

The 2021 Lexus RX distinguished itself as a luxury SUV that emphasized comfort and reliability, making it an appealing choice for buyers seeking both style and practicality. It featured an excellent ride quality and offered great value for money, ensuring a pleasant driving experience. Additionally, the introduction of new standard safety systems enhanced its appeal by prioritizing passenger protection.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.
  • 2022 Lexus RX: This year offers $40,414.56 average price, 36% good/great deals, 4.6/5 user rating, 7.3/10 expert rating, 2,526 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)
Archie C
5.0
Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Dan F
5.0
Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

Haidar A
5.0
Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W
5.0
Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous
5.0
Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost in San Antonio, TX?

The average 2021 Lexus RX costs about $35,546.03. The average price has decreased by -4.1% since last year. The 99 for sale near San Antonio, TX on CarGurus, range from $23,762 to $49,281 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles in San Antonio, TX have no reported accidents or damage?

99 out of 99 for sale near San Antonio, TX have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2024 Lexus RX in San Antonio TX

  • 2023 Lexus RX in San Antonio TX

  • 2022 Lexus RX in San Antonio TX

  • 2020 Lexus RX in San Antonio TX

  • 2019 Lexus RX

  • 2018 Lexus RX in San Antonio TX

  • Lexus RX 350 FWD

  • Lexus RX 350 AWD in San Antonio TX

  • Lexus RX 350 F Sport AWD

  • Lexus RX 350 F Sport Handling AWD

  • Lexus RX 350L FWD

  • Lexus RX 350L AWD

  • Lexus RX 350 F Sport FWD in San Antonio TX

  • Lexus RX 350L Luxury AWD

  • Lexus RX 350L Luxury FWD

  • Lexus RX 350 F Sport Handling FWD

  • 2021 Lexus RX in Austin TX

  • 2021 Lexus RX in Georgetown TX

  • 2021 Lexus RX in Bryan TX

  • Lexus RX in San Antonio TX

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