Used 2021 GMC Sierra 2500HD for Sale near Rancho Palos Verdes, CA
150 results
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 1,856 currently listed for sale and an average price of $51,304.00, 24.7% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
79.8% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD offers impressive technology and comfort features, competing well against other heavy-duty pickup trucks in its class.
CarGurus Analysis: 2021 GMC Sierra 2500HD

Summary
With 1,856 currently listed for sale and an average price of $51,304.00, 24.7% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
79.8% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD offers impressive technology and comfort features, competing well against other heavy-duty pickup trucks in its class.
Why it stands out
The 2021 GMC Sierra 2500HD is a prominent contender in the heavy-duty pickup truck market, setting itself apart with a blend of robust performance, upscale features, and advanced technology. Notably, this model provides a spacious cabin loaded with modern amenities, aligning with GMC's "Professional Grade" brand identity. Its unique selling point is its luxurious Denali trim, which offers premium interior enhancements not typically found in competitors like the Chevrolet Silverado or even the heavy-duty configurations of the Ford F-Series.
In addition to a powerful engine lineup, including the robust 6.6-liter Duramax turbo-diesel option, the Sierra 2500HD is designed for both comfort and utility. With features like advanced towing capabilities and cutting-edge infotainment systems, it attracts buyers looking for a truck that performs well both in work and leisure settings. However, potential buyers should be aware of some generational issues that could arise, particularly from earlier model years.
Other model years to consider
- Average price: $77,045.00
- Good/great deal percentage: 30.0%
- User rating: 5 / 5
- Total listings: 3,337
- Average price: $70,120.00
- Good/great deal percentage: 29.8%
- User rating: 4 / 5
- Total listings: 3,801
- Average price: $56,617.00
- Good/great deal percentage: 29.1%
- User rating: 4 / 5
- Total listings: 3,516
This analysis is based on CarGurus' proprietary market data from April 20, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.

Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
5.0 Overall rating
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Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| Double Cab LB RWD | $39,000 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLE Crew Cab 4WD | $48,200 |
| SLT Crew Cab 4WD | $56,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
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