Used 2025 Mercedes-Benz E-Class for Sale nearTupelo, MS

Compare 2025 Mercedes-Benz E-Class Trims

The E-Class offers a blend of luxury and performance, with options ranging from budget-friendly to high-performance hybrids.

• Starting at $49,534
• Best MPG/MPGe: 54 city / 65 hwy
• Most Popular: E 350 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

Missing data displayed as "—".

Trim Deep Dives

E 350 RWD — "Who It's For"

The E 350 RWD is the pick for shoppers who want a luxury sedan experience without the added cost of AWD. It's the most budget-friendly option in the lineup.

• Avg. market price: $49,534 (updated weekly)
• MPG/MPGe: 25 city / 33 hwy
• Inventory: 517 listings
• View E 350 RWD listings

E 350 4MATIC — "Who It's For"

The E 350 4MATIC is the pick for shoppers who want all-wheel drive without a significant price increase. It's also the most popular trim in the lineup.

• Avg. market price: $52,619 (updated weekly)
• MPG/MPGe: 24 city / 33 hwy
• Inventory: 940 listings
• View E 350 4MATIC listings

E 450 4MATIC — "Who It's For"

The E 450 4MATIC is the pick for shoppers who want a sportier driving experience with AWD. It offers more power and luxury features.

• Avg. market price: $65,114 (updated weekly)
• MPG/MPGe: 22 city / 31 hwy
• Inventory: 180 listings — lower availability; may limit negotiating room
• View E 450 4MATIC listings

AMG E 53 Hybrid 4MATIC+ — "Who It's For"

The AMG E 53 Hybrid 4MATIC+ is the pick for shoppers who want top-tier performance and efficiency in a luxury sedan. It's the most powerful option available.

• Avg. market price: $85,093 (updated weekly)
• MPG/MPGe: 54 city / 65 hwy
• Inventory: 99 listings — lower availability; may limit negotiating room
• View AMG E 53 Hybrid 4MATIC+ listings

Trim Recommendations

Most Popular — E 350 4MATIC

With 940 active listings, the E 350 4MATIC is the clear volume leader in the lineup.

Browse E 350 4MATIC listings

Best Budget Option — E 350 RWD

At $49,534 avg market price — below the lineup median of $58,866 — it's the most accessible entry point.

Browse E 350 RWD listings

Best for Fuel Economy — AMG E 53 Hybrid 4MATIC+

The AMG E 53 Hybrid 4MATIC+ offers impressive fuel efficiency at 54 city / 65 hwy MPG/MPGe.

Browse AMG E 53 Hybrid 4MATIC+ listings

These recommendations are based on CarGurus' proprietary market data from September 24, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2025 Mercedes-Benz E-Class cost?

Prices have softened 4.35% compared to this time last year, making it a favorable time to shop this model year.

There are 766 listings available, which gives you a solid amount of inventory to compare.

Is the 2025 Mercedes-Benz E-Class a good car?

The 2025 Mercedes-Benz E-Class stands out because it leans hard into technology without giving up the comfort and space that have long defined the name. It has been on sale since spring 2024 and is described as the most technologically advanced version yet, with available features such as a driver-facing camera for Zoom calls or selfies when parked and an augmented-reality satellite navigation display.

The cabin is especially striking, with ambient lighting, a large digital display behind the steering wheel, a 14.4-inch central touchscreen, and an optional third screen for the front passenger. Wireless Apple CarPlay and Android Auto are standard, along with a blind-spot warning system, while the seats, materials, and legroom are all presented as major strengths.

The 2025 lineup is still relatively focused, but it covers a useful spread of performance and efficiency. The E350 sedan uses a 2.0-liter four-cylinder engine with 295 horsepower and mild-hybrid technology, while the E350 4Matic sedan adds all-wheel drive. Above that, the E450 4Matic sedan uses a 3.0-liter inline-six-cylinder engine with 369 horsepower, and all of these models use a nine-speed automatic transmission. For buyers who want something far quicker, the Mercedes-AMG E 53 Hybrid delivers 577 horsepower, 553 lb-ft of torque, and a 0-60 mph time of less than four seconds.

32.8% of listings are priced as good or great deals, so you have a meaningful share of the market to shop from.

Is the 2025 Mercedes-Benz E-Class reliable?

The 2025 Mercedes-Benz E-Class is presented as a comfort-first luxury sedan with strong technology, premium materials, and a refined driving experience. Its appeal centers on the way it combines advanced features with the space and comfort you expect from the nameplate.

The available equipment and broad powertrain spread suggest a well-developed lineup, but you should still approach long-term ownership as a premium-car commitment. For used buyers, that means budgeting carefully for maintenance and repairs over time.

What should I look for when buying a used 2025 Mercedes-Benz E-Class?

Accident-free inventory is excellent at 96.7% — clean inventory, standard diligence applies.

You should still run a vehicle history report and verify that the car’s equipment and service records match the listing. Prioritize a thorough inspection of the cabin electronics, driver-assistance features, and any signs of wear in the seats, trim, and controls.

Is now a good time to buy a used 2025 Mercedes-Benz E-Class?

This looks like a moderate, selective buyer’s market, so you can shop patiently and still find worthwhile options.

• Deal availability: 32.8% of listings are priced as good or great deals.
• Inventory: There are 766 listings available.
• Price trend: Prices have softened 4.35% compared with last year.
• Clean inventory: 96.7% of listings are accident-free.

If you find a listing below $59,575, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2025 Mercedes-Benz E-Class's resale value?

The current average of $59,588 sits slightly below last year's $62,297.

That price movement suggests the market has eased, which can help you buy more selectively today. For a future seller, it also means resale value may depend heavily on condition, mileage, and how well the car is equipped.

Because the current average is still close to the year-round low, a well-kept example should remain easier to position than one with visible wear or missing features. If you buy carefully now, you give yourself a better chance of protecting value later.

Should I buy a 2025 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2025 against nearby model years, here's how to think about it:

Choose the 2025 if:

• 32.8% of listings are priced as good or great deals.
• Accident-free inventory is excellent at 96.7% — clean inventory, standard diligence applies.
• Price trend: Prices have softened 4.35% compared with last year.

Consider the 2024 if:

• At $54,898, the 2024 costs less than the current year's $59,588 average.
• It brings a redesigned cabin with refined ride quality and premium materials.

Consider the 2026 if:

• It adds a standard fingerprint scanner and a wagon option for more utility.

The bottom line: If you want the strongest mix of modern tech, comfort, and current-market availability, the 2025 is the primary year to target. If price matters most, the 2024 is the better value play, while the 2026 makes sense if you want the newest features and can stretch for them.

These recommendations are based on CarGurus' proprietary market data from September 22, 2026, CarGurus experts' opinions, and generative AI.