Used 2025 Mercedes-Benz E-Class E 450 4MATIC for SaleNationwide
33 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 4,316
- Stock #:
- 260416B
- VIN:
- W1KLF6BB2SA100651
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
4,316 mi
Covington, LA
Fair Deal
$65,969
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Neva Grey/Black)
- Transmission:
- Automatic
- Mileage:
- 17,740
- Stock #:
- M628569A
- VIN:
- W1KLF6BB8SA165701
2025 Mercedes-Benz E-Class
E 450 4MATIC
17,740 mi
Bentonville, AR
Fair Deal
$66,124
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Gray (Graphite Grey Metallic)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 43,361
- Stock #:
- U087436
- VIN:
- W1KLF6BB8SA087436
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
43,361 mi
Nashville, TN
Fair Deal
$57,221
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 8,832
- Stock #:
- T70516A
- VIN:
- W1KLF6BB2SA172689
2025 Mercedes-Benz E-Class
E 450 4MATIC
8,832 mi
McKinney, TX
Good Deal
$58,102
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 10,325
- Stock #:
- SZ161
- VIN:
- W1KLF6BBXSA086160
2025 Mercedes-Benz E-Class
E 450 4MATIC
10,325 mi
Tiverton, RI
Good Deal
$64,385
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Nautical Blue Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 17,537
- Stock #:
- TA087585A
- VIN:
- W1KLF6BB3SA087585
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
17,537 mi
Chula Vista, CA
Good Deal
$59,859
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 13,057
- Stock #:
- GA16033
- VIN:
- W1KLF6BB4SA089992
2025 Mercedes-Benz E-Class
E 450 4MATIC
13,057 mi
Germantown, MD
Good Deal
$59,798
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 2,722
- Stock #:
- S60113S
- VIN:
- W1KLF6BB8SA118961
2025 Mercedes-Benz E-Class
E 450 4MATIC
2,722 mi
Doylestown, PA
Great Deal
$62,141
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 9,915
- Stock #:
- SA157763
- VIN:
- W1KLF6BB1SA157763
2025 Mercedes-Benz E-Class
E 450 4MATIC
9,915 mi
Chicago, IL
Good Deal
$60,804
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Gray (Alpine Grey)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 15,920
- Stock #:
- R120927
- VIN:
- W1KLF6BB7SA120927
2025 Mercedes-Benz E-Class
E 450 4MATIC
15,920 mi
Irondale, AL
Good Deal
$64,504
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 1,691
- Stock #:
- P6125
- VIN:
- W1KLF6BB7SA163146
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
1,691 mi
Willoughby, OH
Good Deal
$66,882
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 11,800
- Stock #:
- KTTPSA115776
- VIN:
- W1KLF6BB9SA115776
2025 Mercedes-Benz E-Class
E 450 4MATIC
11,800 mi
Vienna, VA
Good Deal
$59,495
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Sonoran Brown Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Neva Grey/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 3,470
- Stock #:
- P11613
- VIN:
- W1KLF6BB0SA106657
2025 Mercedes-Benz E-Class
E 450 4MATIC
3,470 mi
West Palm Beach, FL
Good Deal
$64,894
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 25,560
- Stock #:
- G03365
- VIN:
- W1KLF6BB1SA105324
2025 Mercedes-Benz E-Class
E 450 4MATIC
25,560 mi
Glenview, IL
Good Deal
$58,000
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 12,782
- Stock #:
- 40X350
- VIN:
- W1KLF6BB8SA144802
2025 Mercedes-Benz E-Class
E 450 4MATIC
12,782 mi
Sycamore, IL
Good Deal
$58,837
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 7,810
- Stock #:
- SA095977
- VIN:
- W1KLF6BB5SA095977
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
7,810 mi
Rockland, MA
Fair Deal
$63,495
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 17,292
- Stock #:
- HI243X
- VIN:
- W1KLF6BB6SA091288
Preparing for a close up...
Photos coming soon
2025 Mercedes-Benz E-Class
E 450 4MATIC
17,292 mi
Little Silver, NJ
Good Deal
$61,795
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Red
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 11,983
- Stock #:
- U135250
- VIN:
- W1KLF6BB5SA135250
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
11,983 mi
Tallahassee, FL
Good Deal
$63,593
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 871
- Stock #:
- 4238U
- VIN:
- W1KLF6BB5SA155711
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
871 mi
Metairie, LA
Fair Deal
$67,995
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 161
- Stock #:
- P085565
- VIN:
- W1KLF6BB9SA085565
New arrival
2025 Mercedes-Benz E-Class
E 450 4MATIC
161 mi
Irondale, AL
Fair Deal
$70,496
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 9,337
- Stock #:
- P11635
- VIN:
- W1KLF6BB8SA156951
2025 Mercedes-Benz E-Class
E 450 4MATIC
9,337 mi
West Palm Beach, FL
Fair Deal
$64,394
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 14,896
- Stock #:
- V55302
- VIN:
- W1KLF6BB0SA155101
2025 Mercedes-Benz E-Class
E 450 4MATIC
14,896 mi
Virginia Beach, VA
Good Deal
$63,581
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 9,036
- Stock #:
- M10893
- VIN:
- W1KLF6BB4SA086560
2025 Mercedes-Benz E-Class
E 450 4MATIC
9,036 mi
Kingsport, TN
No Rating
$59,972
- Year:
- 2025
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 375 hp 3L I6
- Exterior color:
- Nautical Blue Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 5,875
- Stock #:
- QBV746
- VIN:
- W1KLF6BB5SA170676
2025 Mercedes-Benz E-Class
E 450 4MATIC
5,875 mi
Champaign, IL
No Rating
$59,819
FAQs
How much does the Mercedes-Benz E-Class E 450 4MATIC cost?
The average Mercedes-Benz E-Class E 450 4MATIC costs about $60,642.19. The average price has decreased by -0.1% since last year. The 172 for sale on CarGurus range from $37,889 to $88,730 in price.
How many Mercedes-Benz E-Class E 450 4MATIC vehicles have no reported accidents or damage?
159 out of 172 for sale have no reported accidents or damage.
What is the fuel economy of the Mercedes-Benz E-Class E 450 4MATIC?
Depending on the engine and options, the Mercedes-Benz E-Class E 450 4MATIC gets between 25 and 26 MPG (or EV battery range).
What fuel types are available?
Gasoline engines are available.
Relevant articles
CarGurus Editorial Team
The Best Family Sedans of 2026
Advanced safety features that were once exclusive to luxury cars are now standard on many family sedans. And while sedans might not have the space of an SUV or a minivan, they do have efficiency on their side. Here are our top 10.
Jill Ciminillo
2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
George Kennedy
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
All Used CarsManual Transmission CarsLuxury CarsCars with Red InteriorCheap Manual CarsHybrid CarsSports CarsElectric SUVsCheap TrucksSmall CarsThird Row SUVsThree Quarter Ton TrucksLifted TrucksManual Transmission TrucksDiesel TrucksHybrid SUVsDually TrucksOne Ton TrucksCheap SUVsLifted Ford Trucks4x4 TrucksWork TrucksAWD SUVsFord TrucksChevrolet TrucksToyota TrucksTrucks Under $10,000Cars Under $15,000Sports Cars Under $20,000Trucks Under $20,000Used Sedans for Sale with Low MileageUsed SUVs / Crossovers for Sale with Low MileageUsed Hatchbacks for Sale with Low MileageUsed Convertibles for Sale with Low MileageUsed Vans for Sale with Low MileageUsed Minivans for Sale with Low MileageUsed Pickup Trucks for Sale with Low MileageUsed Coupes for Sale with Low MileageUsed Wagons for Sale with Low Mileage
