Used 2025 Mercedes-Benz E-Class for Sale nearSpartanburg, SC

Compare 2025 Mercedes-Benz E-Class Trims

The E-Class offers a blend of luxury and performance, with options ranging from budget-friendly to high-performance hybrids.

• Starting at $50,884
• Best MPG/MPGe: 54 city / 65 hwy
• Most Popular: E 350 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

Missing data displayed as "—".

Trim Deep Dives

E 350 RWD — "Who It's For"

The E 350 RWD is the pick for shoppers who want a luxury sedan experience without the AWD price premium. It's the most budget-friendly option in the lineup.

• Avg. market price: $50,884 (updated weekly)
• MPG/MPGe: 25 city / 33 hwy
• Inventory: 538 listings
• View E 350 RWD listings

E 350 4MATIC — "Who It's For"

The E 350 4MATIC is the pick for shoppers who want all-wheel drive without a significant price increase. It's also the most popular trim in the lineup.

• Avg. market price: $52,839 (updated weekly)
• MPG/MPGe: 24 city / 33 hwy
• Inventory: 882 listings
• View E 350 4MATIC listings

E 450 4MATIC — "Who It's For"

The E 450 4MATIC is the pick for shoppers who want a sportier driving experience with AWD. It offers more power and luxury features.

• Avg. market price: $63,837 (updated weekly)
• MPG/MPGe: 22 city / 31 hwy
• Inventory: 169 listings — lower availability; may limit negotiating room
• View E 450 4MATIC listings

AMG E 53 Hybrid 4MATIC+ — "Who It's For"

The AMG E 53 Hybrid 4MATIC+ is the pick for shoppers who want top-tier performance and efficiency in a luxury sedan. It's the most powerful option available.

• Avg. market price: $85,788 (updated weekly)
• MPG/MPGe: 54 city / 65 hwy
• Inventory: 101 listings — lower availability; may limit negotiating room
• View AMG E 53 Hybrid 4MATIC+ listings

Trim Recommendations

Most Popular — E 350 4MATIC

With 882 active listings, the E 350 4MATIC is the clear volume leader in the lineup.

Browse E 350 4MATIC listings

Best Budget Option — E 350 RWD

At $50,884 avg market price — below the lineup median of $58,338 — it's the most accessible entry point.

Browse E 350 RWD listings

Best for Fuel Economy — AMG E 53 Hybrid 4MATIC+

With an impressive MPG/MPGe of 54 city / 65 hwy, this hybrid excels in efficiency.

Browse AMG E 53 Hybrid 4MATIC+ listings

These recommendations are based on CarGurus' proprietary market data from September 2, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2025 Mercedes-Benz E-Class cost?

Prices have softened 3.96% compared to this time last year, making it a favorable time to shop this model year.

There are 787 listings available, which gives you a meaningful but still limited pool to compare.

If you find a listing below $60,049.78, that's toward the low end of the year-round range and worth acting on quickly.

Is the 2025 Mercedes-Benz E-Class a good car?

The 2025 Mercedes-Benz E-Class leans heavily into technology and comfort, and it presents itself as the latest expression of a long-running luxury benchmark. It has a striking cabin with ambient lighting, a large digital display behind the steering wheel, a 14.4-inch central touchscreen, and an optional third screen for the front passenger.

It also brings standard wireless Apple CarPlay and Android Auto, a blind-spot warning system, mega-comfortable seats, top-quality materials, and vast legroom, which makes it especially appealing if you want a luxury sedan that prioritizes ease and modern features. The lineup is still relatively small, but it covers rear-wheel-drive and all-wheel-drive sedan versions with mild-hybrid technology and a nine-speed automatic transmission.

33.2% of listings are priced as good or great deals, so you have some room to shop selectively.

Is the 2025 Mercedes-Benz E-Class reliable?

The 2025 Mercedes-Benz E-Class is described as the most technologically advanced version yet, and it pairs that with a comfort-focused cabin and a relatively simple sedan lineup. It has been on sale since spring 2024, so it is still a very new model in the used market.

That newness can work in your favor if you want a modern luxury car with current tech and a fresh design, but it also means you should expect limited long-term ownership history in the used market. For buyers, that makes careful condition checks especially important before you commit.

What should I look for when buying a used 2025 Mercedes-Benz E-Class?

Accident-free inventory is excellent at 97.1% — clean inventory, standard diligence applies.

You should still run a vehicle history report and confirm the car’s service records, especially because this is a very new model and used examples are scarce. Prioritize an inspection of the electronics, cabin features, and overall condition so you can make sure the technology-heavy interior is working as intended.

Is now a good time to buy a used 2025 Mercedes-Benz E-Class?

This is a moderate, selective buyer’s market: there is inventory to choose from, but the best examples still deserve quick attention.

• Deal availability: 33.2% of listings are priced as good or great deals.
• Inventory: There are 787 listings available.
• Price trend: Prices have softened 3.96% compared with last year.
• Clean inventory: 97.1% of listings are accident-free.

If you find a listing below $60,049.78, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2025 Mercedes-Benz E-Class's resale value?

The current average of $60,146 sits slightly below last year's $62,625.

That decline suggests the market has already moved a bit in your favor if you're buying now, but it also means future resale values may continue to reflect the model’s high starting point and newness. If you plan to sell later, the strongest outcome will likely come from keeping mileage reasonable and the car in excellent condition.

Should I buy a 2025 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2025 against nearby model years, here's how to think about it:

Choose the 2025 if:

• 33.2% of listings are priced as good or great deals.
• Accident-free inventory is excellent at 97.1% — clean inventory, standard diligence applies.
• Price trend: Prices have softened 3.96% compared with last year.

Consider the 2024 if:

• At $55,317, the 2024 costs less than the current year's $60,146 average.
• It brings a redesigned cabin with strong technology and a refined, soothing driving feel.

Consider the 2026 if:

• It adds a standard fingerprint scanner and a more versatile wagon-focused lineup.
• It expands appeal for buyers who want more utility without giving up modern tech.

The bottom line: If you want the newest used E-Class with the freshest tech and a still-healthy share of good deals, the 2025 is the primary pick. If your priority is saving money, the 2024 is the smarter value play, while the 2026 makes sense if you want the newer feature set and wagon versatility.

These recommendations are based on CarGurus' proprietary market data from September 4, 2026, CarGurus experts' opinions, and generative AI.