Used 2022 Mercedes-Benz S-Class for Sale near Pittsburgh, PA
241 results
![[799] MANUFAKTUR Diamond White Metallic 2022 Mercedes-Benz S-Class S 580 4MATIC AWD Sedan All-Wheel Drive Automatic](https://static.cargurus.com/images/forsale/2026/04/18/14/01/2022_mercedes-benz_s-class-pic-974518954080127668-1024x768.jpeg?io=true&width=640&height=480&fit=bounds&format=jpg&auto=webp)
CarGurus Analysis:
2022 Mercedes-Benz S-Class
- With 250 currently listed for sale near Pittsburgh, PA and an average price of $70,688.00, 20.0% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
- Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
- 88.4% of 2022 S-Class models on CarGurus are accident free.
- The 2022 Mercedes-Benz S-Class features a sleek design, luxurious interior materials, and modern technology, including advanced driver-assistance systems.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall
Summary
- With 250 currently listed for sale near Pittsburgh, PA and an average price of $70,688.00, 20.0% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
- Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
- 88.4% of 2022 S-Class models on CarGurus are accident free.
- The 2022 Mercedes-Benz S-Class features a sleek design, luxurious interior materials, and modern technology, including advanced driver-assistance systems.
Why it stands out
The 2022 Mercedes-Benz S-Class stands as a model of modern executive transportation, seamlessly blending luxury with cutting-edge technology. Its impressive array of features includes a 48-volt mild hybrid gasoline-electric powertrain with either a turbocharged 3.0-liter inline-six-cylinder or a twin-turbo 4.0-liter V8 engine, depending on the variant. This combination not only enhances performance—with the S500 achieving 0-60 mph in just 4.9 seconds—but also offers impressive fuel economy figures, up to 21 mpg city and 30 mpg highway for the S500 model. The interior is a showcase of meticulous craftsmanship, featuring high-quality materials, an expansive 12.8-inch OLED touchscreen, and a 12.3-inch digital instrument panel that integrates advanced tech features like augmented reality navigation. Safety remains paramount with innovative systems, including active distance assist and the Magic Vision Control for wiper systems. Although it comes with a high price tag, the distinct blend of style, performance, and luxury that the S-Class offers makes it a compelling choice for discerning buyers looking for a top-tier sedan.
Other model years to consider
- Average price: $47,500.00
- Good/great deal percentage: 31.6%
- User rating: 5 / 5
- Total listings: 234
- Average price: $31,700.00
- Good/great deal percentage: 28.5%
- User rating: 4.79 / 5
- Total listings: 186
- Average price: $24,555.00
- Good/great deal percentage: 33.5%
- User rating: 3.92 / 5
- Total listings: 251
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles
Mercedes-Benz S-Class Buying Guide: Cost, Reliability, and the Best Years to Buy
Discover the ultimate buying guide for purchasing a used Mercedes-Benz S-Class, covering every generation since 1951. Whether you're a first-time buyer or a Mercedes enthusiast, this comprehensive overview will help you research your next pre-owned Mercedes-Benz S-Class.
The Best Sedans of 2026
As more people flock to SUVs and crossovers, some automakers are killing off sedans. But others are doubling down, building some of the best four-door cars we’ve ever driven. For a supposedly dying segment, the sedan market looks awfully healthy.
2026 Mercedes-Benz S-Class Pricing, Specs, and Release Date
Mercedes-Benz avoids drastic change with the 2026 S-Class sedan and instead refines the lineup with updated packages and configurations, plus a host of new paint colors and interior treatments.
4.5 Overall rating
Filter by rating
Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
See more price trends
