Used 2022 Mercedes-Benz S-Class for Sale nearColorado Springs, CO

Compare 2022 Mercedes-Benz S-Class Trims in Colorado Springs, CO

The S-Class offers a blend of luxury and performance, with options ranging from the value-focused S 500 to the high-end Maybach trims.

• Starting at $67,540
• Best MPG/MPGe: 21 city / 30 hwy
• Most Popular: S 580 4MATIC AWD

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

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Trim Deep Dives

S 500 4MATIC AWD — "Who It's For"

The S 500 is the pick for shoppers who want luxury features without the higher price of the S 580. It's a great entry point into the S-Class.

• Avg. market price: $67,540 (updated weekly)
• MPG/MPGe: 21 city / 30 hwy
• Inventory: 48 listings
• View S 500 4MATIC AWD listings

S 580 4MATIC AWD — "Who It's For"

The S 580 is the pick for shoppers who want a powerful V8 engine and advanced features without stepping up to the Maybach. It's the most popular trim in the lineup.

• Avg. market price: $67,540 (updated weekly)
• MPG/MPGe: 16 city / 25 hwy
• Inventory: 79 listings
• View S 580 4MATIC AWD listings

Maybach S 580 4MATIC AWD — "Who It's For"

The Maybach S 580 is the pick for shoppers who want unparalleled luxury and comfort without going for the top-tier Maybach S 680.

• Avg. market price: $67,540 (updated weekly)
• MPG/MPGe: 15 city / 24 hwy
• Inventory: 14 listings — lower availability; may limit negotiating room
• View Maybach S 580 4MATIC AWD listings

Maybach S 680 4MATIC AWD — "Who It's For"

The Maybach S 680 is the pick for shoppers who want the ultimate in luxury and performance, featuring a powerful V12 engine and exclusive features.

• Avg. market price: $67,540 (updated weekly)
• MPG/MPGe: 12 city / 21 hwy
• Inventory: 14 listings — lower availability; may limit negotiating room
• View Maybach S 680 4MATIC AWD listings

Trim Recommendations

Most Popular — S 580 4MATIC AWD

With 79 active listings, the S 580 4MATIC AWD is the clear volume leader in the lineup.

Browse S 580 4MATIC AWD listings

Best Budget Option — S 500 4MATIC AWD

At $67,540 avg market price — below the lineup median of $67,540 — it's the most accessible entry point.

Browse S 500 4MATIC AWD listings

Closing Attribution

These recommendations are based on CarGurus' proprietary market data from October 15, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2022 Mercedes-Benz S-Class cost?

Prices have softened 11.52% compared to this time last year, making it a favorable time to shop this model year.

There are 1,136 listings available, which gives you a meaningful pool to compare prices and equipment.

Is the 2022 Mercedes-Benz S-Class a good car?

Yes — the 2022 Mercedes-Benz S-Class earns a 4.5/5 user rating and an 8.67/10 expert rating. The model scores 9/10 across Look and feel, Form and function, Technology, and Safety.

It’s a full-size luxury sedan aimed at executive transportation, and the data backs up that mission with a stylish design, great ride quality, and premium interior materials. You also get two powertrain choices, with a turbocharged inline-six in the S500 and a twin-turbo V8 in the S580, plus all-wheel drive and a nine-speed automatic.

The main trade-offs are the potentially polarizing design and the high price tag. Even so, 33.2% of listings are priced as good or great deals, which suggests there are still some attractive opportunities if you shop carefully.

Is the 2022 Mercedes-Benz S-Class reliable?

Owners rate it 4.5/5, a strong signal of long-term satisfaction.

The S-Class is positioned as Mercedes-Benz’s flagship sedan, and the available information emphasizes refinement, advanced technology, and a thoroughly premium cabin. Its mild-hybrid powertrains are described as seamless, with the electric motor contributing extra horsepower and torque during acceleration, which supports a polished driving experience.

Mercedes also highlights the car’s executive-level engineering and comfort-focused setup, including a smooth ride and responsive handling. The first scheduled maintenance visit is on the house, which helps soften early ownership costs.

For used buyers, the main long-term risk is less about the concept and more about the complexity and expense that can come with a high-end luxury sedan.

What should I look for when buying a used 2022 Mercedes-Benz S-Class?

Accident-free inventory is solid at 86.7% — always verify the vehicle history report.

You should still check the history report carefully, because a clean listing percentage does not replace a full records review. Prioritize a pre-purchase inspection that focuses on electronics, suspension behavior, and signs of expensive wear. Pay close attention to condition, since this is a luxury sedan where neglected maintenance can be costly.

Key things to evaluate:

• Trim level: The S500 and S580 both emphasize luxury, but the S-Class’s cabin presentation and feature content make the higher trims and packages more compelling if you want the richest experience.
• Powertrain: You can choose between a turbocharged 3.0-liter inline-six with EQ Boost or a twin-turbo 4.0-liter V8 with EQ Boost, both paired with a nine-speed automatic and standard all-wheel drive.
• Safety package: The standard driver-assistance suite includes adaptive cruise control with route-based speed adaptation, stop-and-go assist, steering assist, emergency stop assist, lane-change assistant, brake assist with cross-traffic and turn-off functions, speed limit assist with traffic sign assist, blind-spot assist with exit warning, lane-keeping assist, parking assist with Parktronic, Pre-Safe Plus with Pre-Safe Sound, Pre-Safe Impulse Side, and car-to-x communication.
• Infotainment: The cabin centers on a 12.8-inch OLED touchscreen with the MBUX system, paired with a 12.3-inch digital instrument panel and standard augmented video for navigation.
• Fuel efficiency: The S500 is rated at up to 21 mpg city/30 mpg highway/24 mpg combined, while the S580 is rated at 16 mpg city/25 mpg highway/19 mpg combined.

Which 2022 Mercedes-Benz S-Class trim should I buy?

The 2022 Mercedes-Benz S-Class is offered in 5 trim levels: S500 Luxury Line, S500 AMG Line, S580 Luxury Line, S580 AMG Line, and S580 Executive Line.

Here's the short version:

• S500 Luxury Line: This is the entry point, and it gives you the core S-Class experience at the lowest starting price. It suits you best if you want the flagship sedan’s comfort and technology without stretching for the more expensive appearance or executive packages.
• S500 AMG Line: This is the best-value trim for many shoppers because it adds a sportier presentation while keeping the more efficient six-cylinder powertrain. Choose it if you want a more distinctive look without moving up to the V8.
• S580 Luxury Line: This trim is for you if you want the stronger V8 powertrain and the S-Class experience in its most traditional luxury form. It makes sense if performance and smoothness matter more than price.
• S580 AMG Line: This is the step up if you want the V8 plus a more aggressive appearance package. It’s the right pick if you want the most visual presence without going all the way to the top executive trim.
• S580 Executive Line: This is the most upscale choice in the lineup and the one to consider if you want the fullest luxury focus. It’s the trim to target if rear-seat comfort and a more complete flagship feel matter most.

The standard safety and driver-assistance equipment is extensive across the lineup, so you’re mainly choosing between powertrain, appearance, and executive-level luxury content.

Is now a good time to buy a used 2022 Mercedes-Benz S-Class?

This is a moderate market for selective buyers, with enough inventory to shop carefully and enough price softness to create opportunities.

• Deal availability: 33.2% of listings are priced as good or great deals.
• Inventory: There are 1,136 listings available.
• Price trend: Prices have softened 11.52% compared with last year.
• Clean inventory: 86.7% of listings are accident-free.

If you find a listing below $62,063, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz S-Class's resale value?

The current average of $62,063 sits slightly below last year's $70,147.

That decline suggests the market has already adjusted downward, which can help you buy at a more favorable entry point today. For a future seller, the key question is whether the model’s luxury appeal and flagship status can stabilize demand after the recent price drop.

Because the S-Class is a high-end sedan with strong brand recognition, well-kept examples should still attract serious shoppers. But the high original price and expensive ownership profile mean condition and equipment will matter a lot when it’s time to resell.

Vehicles with strong owner satisfaction ratings, like this model year's 4.5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz S-Class safe?

The S-Class gets loaded with standard and available safety and advanced driver assistance systems, with some executive-level upgrades for the second row.

It earns a 9/10 safety score from our experts.

The standard safety suite includes active distance assist Distronic adaptive cruise control with route-based speed adaptation, active stop-and-go assist, active steering assist with active emergency stop assist and active lane-change assistant, active brake assist with cross-traffic function and turn-off function, active speed limit assist with traffic sign assist, active blind-spot assist with exit warning, active lane-keeping assist, active parking assist with Parktronic, Pre-Safe Plus with Pre-Safe Sound, Pre-Safe Impulse Side, and car-to-x communication. Magic Vision Control is also standard.

You can also get rear-passenger airbags and a rear-seat belt bag, along with easy adjust headrests with occupant restraint protection. The safety setup is broad and advanced, though some of the more executive-focused protection features are reserved for the rear seat.

Should I buy a 2022 Mercedes-Benz S-Class or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 33.2% of listings are priced as good or great deals.
• Accident-free inventory is solid at 86.7% — always verify the vehicle history report.
• Price trend: Prices have softened 11.52% compared with last year.
• Owners rate it 4.5/5 — a strong satisfaction signal.
• It combines a mild-hybrid six-cylinder or V8 powertrain with a deeply luxurious cabin and advanced tech.

Consider the 2021 if:

• At $58,029, the 2021 costs less than the current year's $62,063 average.
• It brings a major redesign with updated infotainment and new powertrains.

Consider the 2023 if:

• At $77,495, the 2023 costs more than the current year's $62,063 average.
• It adds a plug-in hybrid powertrain with impressive electric range.

The bottom line: If you want the best balance of price, luxury, and modern tech, the 2022 is the strongest all-around choice. If you’re more price-sensitive, the 2021 is the value play, while the 2023 makes sense only if you specifically want the plug-in hybrid setup and are comfortable paying more.

These recommendations are based on CarGurus' proprietary market data from October 13, 2026, CarGurus experts' opinions, and generative AI.