Used 2022 Mercedes-Benz GLS for Sale near Saint Louis, MO
156 results
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 146 currently listed for sale near Saint Louis, MO and an average price of $52,600.00, 29.5% of 2022 Mercedes-Benz GLS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars.
87.0% of 2022 GLS models on CarGurus are accident free.
The 2022 Mercedes-Benz GLS boasts a spacious interior, advanced technology features, and a powerful engine, making it a top choice in the luxury SUV market.
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 146 currently listed for sale near Saint Louis, MO and an average price of $52,600.00, 29.5% of 2022 Mercedes-Benz GLS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars.
87.0% of 2022 GLS models on CarGurus are accident free.
The 2022 Mercedes-Benz GLS boasts a spacious interior, advanced technology features, and a powerful engine, making it a top choice in the luxury SUV market.
Why it stands out
The 2022 Mercedes-Benz GLS is a standout in the full-size luxury SUV category, combining high-end luxury with practical utility. Known as the largest SUV in Mercedes' lineup, it provides spacious seating for up to seven passengers and a generous cargo area—key advantages for families and those needing extra space. The GLS 450 model features a robust 3.0-liter turbocharged inline-six engine, delivering 362 horsepower, aided by an EQ Boost mild-hybrid system for enhanced efficiency and performance. The interior is stylish and equipped with the advanced Mercedes-Benz User Experience (MBUX) infotainment system, offering seamless connectivity and voice recognition.
However, it is worth noting that some advanced safety features are not included as standard, which may be a drawback for those seeking comprehensive safety technology. Additionally, while the GLS excels in luxury and power, some reviews mention its ride quality could be improved, as it is reported to exhibit a bit of body motion over bumps. Overall, the 2022 GLS appeals to buyers looking for a blend of luxury, functionality, and performance in a spacious SUV.
Other model years to consider
- Average price: $81,425.00
- Good/great deal percentage: 29.5%
- User rating: 5 / 5
- Total listings: 166
- Average price: $19,995.00
- Good/great deal percentage: 26.7%
- User rating: 4.8 / 5
- Total listings: 165
- Average price: $79,199.00
- Good/great deal percentage: 31.1%
- Total listings: 148
This analysis is based on CarGurus' proprietary market data from June 2, 2026, CarGurus experts' opinions, and generative AI.
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5.0 Overall rating
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rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
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