Used 2022 Mercedes-Benz GLS for Sale nearMobile, AL
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 93,547
- Stock #:
- 04P369007
- VIN:
- 4JGFF5KE1MA369007

Sponsored Listing
2021 Mercedes-Benz GLS
450 4MATIC
93,547 mi
$33,723
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 87,162
- Stock #:
- I59068P
- VIN:
- 4JGFF5KE1NA659068

Sponsored Listing
2022 Mercedes-Benz GLS
450 4MATIC
87,162 mi
$34,960
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 87,162
- Stock #:
- I59068P
- VIN:
- 4JGFF5KE1NA659068

2022 Mercedes-Benz GLS
450 4MATIC
87,162 mi
$34,960
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,043
- Stock #:
- 944834
- VIN:
- 4JGFF5KE2PA944834

-$1,600
2023 Mercedes-Benz GLS
450 4MATIC
30,043 mi
$58,462
$56,862
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 93,395
- Stock #:
- PM2997
- VIN:
- 4JGFF8KE7MA329256

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
93,395 mi
$50,957
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 61,816
- Stock #:
- 7538
- VIN:
- 4JGFF5KE8PA900613

2023 Mercedes-Benz GLS
450 4MATIC
61,816 mi
$46,299
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,225
- Stock #:
- D2126A
- VIN:
- 4JGFF5KE4NA664359

2022 Mercedes-Benz GLS
450 4MATIC
64,225 mi
$44,809
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Iridium Silver Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,602
- Stock #:
- 64252
- VIN:
- 4JGFF8KE5MA357220

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
47,602 mi
$68,130
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,015
- Stock #:
- 004717
- VIN:
- 4JGFF8GE4PB004717

2023 Mercedes-Benz GLS
580 4MATIC
30,015 mi
$64,190
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 35,395
- Stock #:
- X947120
- VIN:
- 4JGFF8KE9PA947120

2023 Mercedes-Benz GLS
AMG GLS 63 4MATIC
35,395 mi
$80,754
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Silver
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (BEIGE)
- Transmission:
- Automatic
- Mileage:
- 43,135
- Stock #:
- 14349
- VIN:
- 4JGFF8KE2MA387808

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
43,135 mi
$65,414
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,140
- Stock #:
- 25837B
- VIN:
- 4JGFF5KE1NA762393

2022 Mercedes-Benz GLS
450 4MATIC
21,140 mi
$51,970
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,889
- Stock #:
- 2469UBA
- VIN:
- 4JGFF5KE6PA921797

2023 Mercedes-Benz GLS
450 4MATIC
29,889 mi
$59,570
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 146 currently listed for sale near Mobile, AL and an average price of $34,500, 47.9% of 2022 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
87.7% of 2022 GLS models on CarGurus are accident free.
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 99,103
- Stock #:
- NV618337A
- VIN:
- 4JGFF5KE2MA464434

2021 Mercedes-Benz GLS
450 4MATIC
99,103 mi
$30,118
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 62,722
- Stock #:
- INC2867
- VIN:
- 4JGFF8GEXMA388049

2021 Mercedes-Benz GLS
580 4MATIC
62,722 mi
$48,023
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 42,019
- Stock #:
- L350429A
- VIN:
- 4JGFF5KE2NA593517

-$2,000
2022 Mercedes-Benz GLS
450 4MATIC
42,019 mi
$46,707
$44,707
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Tartufo Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,472
- Stock #:
- NU3804
- VIN:
- 4JGFF5KEXNA696782

2022 Mercedes-Benz GLS
450 4MATIC
64,472 mi
$43,709
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 86,397
- Stock #:
- 1T576568
- VIN:
- 4JGFF5KE2MA576568

2021 Mercedes-Benz GLS
450 4MATIC
86,397 mi
$34,954
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 60,278
- Stock #:
- 824083
- VIN:
- 4JGFF5KE1NA824083

2022 Mercedes-Benz GLS
450 4MATIC
60,278 mi
$42,196
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 60,621
- Stock #:
- S19786A
- VIN:
- 4JGFF8GE3MA386739

2021 Mercedes-Benz GLS
580 4MATIC
60,621 mi
$47,782
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Diamond White Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 52,193
- Stock #:
- 7091
- VIN:
- 4JGFF8KE6MA433088

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
52,193 mi
$66,687
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 93,547
- Stock #:
- 04P369007
- VIN:
- 4JGFF5KE1MA369007

2021 Mercedes-Benz GLS
450 4MATIC
93,547 mi
$33,723
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 86,623
- Stock #:
- 10804
- VIN:
- 4JGFF5KE2NA585952

2022 Mercedes-Benz GLS
450 4MATIC
86,623 mi
$38,125
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 146 currently listed for sale near Mobile, AL and an average price of $34,500, 47.9% of 2022 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
87.7% of 2022 GLS models on CarGurus are accident free.
Why it stands out
The 2022 Mercedes-Benz GLS sits at the top of Mercedes’ luxury SUV range and is the brand’s biggest SUV. Its “S” designation signals that it is meant to be the SUV equivalent of Mercedes’ flagship S-Class sedan, which helps explain why the GLS is positioned as a full-size luxury statement rather than just a practical family hauler. Mercedes also says the flagship SUV is big on both luxury and utility, and that combination is central to its appeal.
For 2022, Mercedes withdrew most of its V8 models from the United States, leaving only the base six-cylinder GLS 450 4Matic model. That makes this version of the GLS notable for being the only one available at the time of testing, and it still brings the strengths highlighted in the test drive data: stylish design, a powerful engine, and a spacious cabin. Those qualities make it easy to see why buyers would be drawn to it if they want a large, upscale SUV with a strong presence and plenty of room.
The tradeoffs are just as important. The test drive data points to poor ride quality, advanced safety features that are not standard, and poor ergonomic design. So while the 2022 Mercedes-Benz GLS stands out for luxury, size, and utility, it also asks buyers to accept some comfort and usability compromises.
Other model years to consider
- Average price: $63,299
- Good/great deal percentage: 34.7%
- User rating: 5 / 5
- Total listings: 190
- Average price: $22,703
- Good/great deal percentage: 43.6%
- User rating: 4.8 / 5
- Total listings: 163
- Average price: $38,990
- Good/great deal percentage: 44.5%
- User rating: 4.67 / 5
- Total listings: 128
This analysis is based on CarGurus' proprietary market data from September 14, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
See more price trends2022 Mercedes-Benz GLS Pricing Analysis: Mobile, AL Market Report
Pricing by Nearby Locations
Market Area: Mobile, AL
Key Insights
- Highest Prices in New Orleans: The average price in New Orleans, LA ($43,990) indicates a premium market, likely driven by demand for luxury vehicles.
- Best Value in Atmore: Atmore, AL ($33,994) offers the lowest average price, suggesting a more price-sensitive consumer base or higher inventory turnover.
- Inventory Levels: With 160 listings in Atmore, the market shows a healthy supply, which may contribute to competitive pricing.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Atmore, AL | 160 | $33,994 |
| Slidell, LA | 138 | $43,990 |
| New Orleans, LA | 137 | $43,990 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 450 4MATIC is the most listed trim with 314 listings, indicating strong demand for this configuration.
- Price Range: The AMG GLS 63 4MATIC has the highest MSRP at $135,400, reflecting its luxury features and performance capabilities.
- AWD Dominance: All trims are AWD, catering to consumer preferences for all-weather capability.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 314 | $77,850 | AWD | 3.0L 362 hp I6 |
| 580 4MATIC | 36 | $101,250 | AWD | 4.0L 483 hp V8 |
| AMG GLS 63 4MATIC | 64 | $135,400 | AWD | 4.0L 603 hp V8 |
| 600 Mercedes-Maybach 4MATIC | 58 | $165,100 | AWD | 4.0L 550 hp V8 |
Pricing Analysis by Model Year
Key Insights
- New Model Premium: The 2025 model is priced at $95,454, which is approximately 6.5% above MSRP, indicating strong demand for the latest model.
- Significant Depreciation: The 2019 model shows a steep decline, with an average price of $21,586, reflecting a depreciation of ~69% from its original MSRP.
- Best Value Years: The 2021 model offers a balance of price and features, priced at $38,990, which is ~48.7% below MSRP, making it an attractive option for buyers.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2025 Mercedes-Benz GLS | $89,200 | $95,454 | +6.5% |
| 2024 Mercedes-Benz GLS | $87,000 | $63,299 | -27.3% |
| 2021 Mercedes-Benz GLS | $76,000 | $38,990 | -48.7% |
| 2020 Mercedes-Benz GLS | $75,200 | $32,338 | -57.0% |
| 2019 Mercedes-Benz GLS | $70,150 | $21,586 | -69.2% |
| 2018 Mercedes-Benz GLS | $69,550 | $22,703 | -67.4% |
| 2017 Mercedes-Benz GLS | $67,050 | $16,652 | -75.2% |
These recommendations are based on CarGurus' proprietary market data from September 16, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2022 Mercedes-Benz GLS cost?
| Metric | Value |
|---|---|
| Current Average Price | $47,558 |
| Year-Round Low | $47,558 |
| Year-Round High | $55,842 |
| Average Price a Year Ago | $55,844 |
| Change vs. Last Year | −14.84% |
Prices have softened 14.84% compared to this time last year, making it a favorable time to shop this model year.
There are 861 listings available, which suggests you should have a workable range of choices.
Is the 2022 Mercedes-Benz GLS a good car?
Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.33/10 expert rating. The standout strength is Look and feel at 9/10.
The GLS is positioned as Mercedes’ flagship SUV, so you’re shopping for a full-size luxury statement rather than a simple family hauler. The overview and test-drive notes both point to a stylish design, a powerful engine, and a spacious cabin, which fit that role well.
The trade-offs are worth weighing: poor ride quality and poor ergonomic design show up in the expert notes, and advanced safety features are not standard. If you want a large, upscale SUV with a strong presence and room to spare, the GLS fits that use case well.
37.2% of listings are priced as good or great deals, so there is some room to shop selectively.
Is the 2022 Mercedes-Benz GLS reliable?
Owners rate it 5/5, a strong signal of long-term satisfaction.
The GLS is described as a luxury SUV with a strong emphasis on comfort, utility, and upscale presentation, and the expert notes also highlight a smooth inline-six layout that suits a luxury vehicle. The mild-hybrid setup is presented as helping with start/stop behavior and reducing engine workload, which supports everyday drivability.
Mercedes also notes that the electric motor powers most accessories, which can help ease the engine’s burden in normal use. For used buyers, the main long-term ownership risk is that a large, complex luxury SUV can become expensive if prior maintenance or repairs were neglected.
What should I look for when buying a used 2022 Mercedes-Benz GLS?
Accident-free inventory is solid at 86.9% — always verify the vehicle history report.
You should still check the vehicle history report carefully, even when the market looks clean overall. A pre-purchase inspection should focus on ride quality, interior ergonomics, and any signs that the vehicle has been used hard or maintained inconsistently. It also makes sense to confirm which convenience and driver-assistance features are actually installed, since some important items were optional.
Key things to evaluate:
- Trim level: The base GLS 450 form is described as more subtle and less flashy than some rivals, and the test car’s fairly basic interior lacked reclining seats. That means you should pay close attention to whether the example you’re considering has the comfort and luxury equipment you want.
- Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline six-cylinder engine with a nine-speed automatic transmission and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft available in short bursts.
- Safety package: Standard equipment includes forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features are extra.
- Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM satellite radio, and natural-language voice recognition. A head-up display is optional.
- Fuel efficiency: EPA fuel economy is 20 mpg combined (18 mpg city, 24 mpg highway).
Which 2022 Mercedes-Benz GLS trim should I buy?
The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.
Here's the short version:
The GLS 450 4Matic is the only version available for this model year in the provided data, so your decision is really about finding the right example rather than choosing between trims. It brings the core GLS strengths: a powerful inline-six, standard AWD, standard air suspension, and a well-equipped MBUX cabin.
The best-value path is to focus on a clean, well-optioned GLS 450 4Matic with the comfort and safety features you care about most, since some key items remain optional. Safety-package gaps are important here: adaptive cruise control, lane-keep assist, second-row side airbags, and other advanced driver-assistance features are not standard.
Is now a good time to buy a used 2022 Mercedes-Benz GLS?
This looks like a moderate, selective buyer’s market, so you can shop with some leverage if you stay patient.
- Deal availability: 37.2% of listings are priced as good or great deals.
- Inventory: There are 861 listings available.
- Price trend: Prices have softened 14.84% compared with last year.
- Clean inventory: 86.9% of listings are accident-free.
If you find a listing below $47,558, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2022 Mercedes-Benz GLS's resale value?
The current average of $47,558 sits slightly below last year's $55,844.
That decline suggests the market has already adjusted downward, which can help you buy at a more favorable entry point. For a future seller, it also means you should expect resale value to depend heavily on condition, mileage, and equipment rather than on broad market momentum alone.
Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.
Is the 2022 Mercedes-Benz GLS safe?
It earns a 6/10 safety score from our experts.
Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also includes a system that can warn if it’s unsafe to open a door when parked.
You should note that adaptive cruise control, lane-keep assist, second-row side airbags, and several more advanced driver-assistance features are optional rather than standard. That means you’ll want to verify the exact equipment on any used example you’re considering.
Should I buy a 2022 Mercedes-Benz GLS or consider a different year?
If you're weighing the 2022 against nearby model years, here's how to think about it:
Choose the 2022 if:
- 37.2% of listings are priced as good or great deals.
- Accident-free inventory is solid at 86.9% — always verify the vehicle history report.
- Price trend: Prices have softened 14.84% compared with last year.
- Owners rate it 5/5 — a strong satisfaction signal.
- Mercedes withdrew most V8 models for this year, leaving the GLS 450 as the only version available at the time of testing.
Consider the 2021 if:
- At $47,795, the 2021 costs more than the current year's $47,558 average.
- It emphasizes comfort above all else.
The bottom line: If you want the better current-market value, the 2022 is the cleaner buy because prices have eased and inventory is available. If you’re mainly comparing on price, the 2021 does not offer a lower average entry point here, so the 2022 is the more compelling starting point unless you find a particularly strong 2021 example.
These recommendations are based on CarGurus' proprietary market data from September 15, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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