How much does the 2022 Mercedes-Benz E-Class cost?

Prices have softened 6.01% compared to this time last year, making it a favorable time to shop this model year.

There are 1,054 listings available, which suggests solid inventory for comparison shopping.

If you find a listing below $40,430.62, that's toward the low end of the year-round range and worth acting on quickly.

Is the 2022 Mercedes-Benz E-Class a good car?

Yes — the 5/5 user rating points to strong owner satisfaction, and the expert rating is 8.17/10. The standout strength is Safety at 10/10.

The 2022 E-Class fits buyers who want a luxury car with a broad mix of performance, comfort, and advanced technology. The overview also highlights multiple body styles, including sedan and convertible options, so you can tailor the car to how you plan to use it.

The market shows 33.7% of listings as good or great deals, which gives you some room to shop selectively.

Is the 2022 Mercedes-Benz E-Class reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The overview points to a model that blends performance, comfort, and advanced technology, while the expert test drive notes a turbocharged four-cylinder and six-cylinder lineup that keeps the car robust without relying on the V8 engines that were dropped from much of the lineup. The performance writeup also emphasizes the mild-hybrid system’s role in improving both power output and efficiency.

Mercedes also includes a first scheduled maintenance visit on the house, which helps soften early ownership costs. For used buyers, the main long-term risk is that a luxury car with this much technology can become expensive if prior maintenance was skipped.

What should I look for when buying a used 2022 Mercedes-Benz E-Class?

Accident-free inventory is solid at 86% — always verify the vehicle history report.

You should still check the history report carefully, because even a strong accident-free rate does not guarantee the individual car you’re considering has a clean past. Prioritize a pre-purchase inspection, especially if the car has complex options or has been driven hard. Focus on condition details that matter most in a luxury car: electronics, interior wear, and evidence of proper maintenance.

Key things to evaluate:

• Trim level: The base E350 sedan starts with a turbocharged four-cylinder, while E450 versions add a turbo 3.0-liter inline-six with EQ Boost. The AMG-tuned versions bring a more aggressive look and feel, but the base form is described as relatively plain.
• Powertrain: The lineup uses turbocharged four-cylinder and six-cylinder engines, with EQ Boost mild-hybrid technology on the six-cylinder. The AMG-tuned 3.0-liter turbo-six makes 429 horsepower and 384 pound-feet of torque.
• Safety package: Standard equipment includes forward collision warning with pedestrian detection, automatic emergency braking, blind-spot monitoring, and rear cross-traffic alert. Most other driver aids are bundled into the Driver Assistance Package, which adds adaptive cruise control, lane-centering assistance, lane keeping, blind-spot assist, and emergency stop assist.
• Infotainment: The MBUX system uses dual 12.3-inch screens and supports Apple CarPlay and Android Auto. WiFi service and augmented reality navigation are available upgrades.
• Fuel efficiency: The mild-hybrid setup is designed to improve efficiency, and the overview says the engine lineup enhances fuel efficiency while maintaining robust performance.

Which 2022 Mercedes-Benz E-Class trim should I buy?

The 2022 Mercedes-Benz E-Class is offered in 4 trim levels: E350, E450, AMG E53, and E53 Cabriolet.

Here's the short version:

• Base trim: The E350 is the most straightforward choice, but it lacks the more dramatic styling and extra performance of the AMG variants. The base form is also described as almost devoid of character compared with higher-spec versions.
• Sweet-spot trim: The E450 is the best value if you want the turbocharged inline-six and EQ Boost without stepping all the way into AMG pricing. It keeps the luxury feel while adding stronger performance over the base engine.
• Premium/top trim: The E53 Cabriolet is the most indulgent choice, pairing AMG performance with the convertible body style, upscale materials, and a richly equipped cabin.
• Off-road trim: The All-Terrain wagon is mentioned as a body style, but it is not the right fit for most daily drivers if you want the classic E-Class luxury experience.

The Driver Assistance Package is the safety add-on worth seeking out if you want the fullest set of driver aids.

Is now a good time to buy a used 2022 Mercedes-Benz E-Class?

This is a moderate, selective buyer’s market, so you can shop carefully without expecting every listing to be a bargain.

• Deal availability: 33.7% of listings are priced as good or great deals.
• Inventory: There are 1,054 listings available.
• Price trend: Prices have softened 6.01% compared with last year.
• Clean inventory: 86.0% of listings are accident-free.

If you find a listing below $40,430.62, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz E-Class's resale value?

The current average of $40,672 sits slightly below last year's $43,273.

That price movement suggests the market has already adjusted downward, which can help you buy at a more favorable point in the cycle. For a future seller, that also means resale value will depend heavily on condition, mileage, and equipment. Well-kept examples with desirable features should hold up better than neglected ones.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz E-Class safe?

It earns 10/10 safety score from our experts.

The E-Class comes with standard forward collision warning with pedestrian detection, automatic emergency braking, blind-spot monitoring, and rear cross-traffic alert. The E-Class Cabriolet also adds pop-up rollbars for rollover protection. Mercedes Pre Safe and Pre Safe Sound are standard as well, and the Driver Assistance Package adds adaptive cruise control, lane-centering assistance, lane keeping, blind-spot assist, emergency stop assist, and rear collision preparation.

The expert test drive also notes that the package is especially impressive in practice, with adaptive cruise control and Active Steering Assist standing out. For used shoppers, the main safety caveat is that many of the most advanced driver aids are not standard and depend on the right package.

Should I buy a 2022 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 33.7% of listings are priced as good or great deals.
• Accident-free inventory is solid at 86% — always verify the vehicle history report.
• Price trend: Prices have softened 6.01% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• The 2022 lineup drops V8-powered variants and focuses on turbocharged four-cylinder and six-cylinder engines.

Consider the 2021 if:

• At $38,650, the 2021 costs less than the current year's $40,672 average.
• It offers a broad, practical, and versatile lineup with four body styles and multiple engines.

The 2022 is the better pick if you want the newer-year market position and the updated lineup. If your priority is saving money, the 2021 is the more budget-friendly path and still gives you much of the E-Class appeal.

These recommendations are based on CarGurus' proprietary market data from August 7, 2026, CarGurus experts' opinions, and generative AI.