CarGurus Logo Homepage Link
  • Buy
    • Used cars
    • New cars
    • Certified pre-owned
    • Start your purchase online
    • Dealerships near me
  • Sell
    • Sell my car
    • Car values
    • Sell my car FAQs
  • Finance
    • Prequalify for financing
    • How does it work?
    • Financing FAQs
  • Research
    • Test drive reviews
    • Price trends
    • Tips & advice
    • Electric cars
    • Compare cars
  • Discover
    The latest way to shop:
    smarter research, better
    listings.
  • Saved cars & searches
  • Sign in / Register
    • My account
    • Saved searches
    • Saved cars
    • Recommended cars
    • Browsing history
    • Financing dashboard
      • United States (EN)
      • Estados Unidos (ES)
      • Canada (EN)
      • Canada (FR)
      • United Kingdom

Used 2022 Lexus RX for Sale near Irvine, CA

185 results
Irvine, CA
2023 Lexus RX 350 Premium FWD Weir Canyon Honda & Acura

2023 Lexus RX

350 Premium FWD

20,930 miles

$42,495

Good Deal
Anaheim, CA
13 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Blue
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
8-Speed Automatic
Mileage:
20,930
Stock number:
00422950
VIN:
JTJCHMAA2P2006544

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

82,130 miles

$32,951

Fair Deal
Cerritos, CA
21 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
82,130
Stock number:
NC245068
VIN:
2T2HZMAA7NC245068

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

22,514 miles

$34,488

Great Deal
Laguna Niguel, CA
12 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
22,514
Stock number:
H202554
VIN:
2T2AZMAAXMC202554

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

62,210 miles

$34,995

Fair Deal
Signal Hill, CA
24 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
62,210
Stock number:
25581T
VIN:
2T2HZMAA2NC245771

2021 Lexus RX 350 AWD

2021 Lexus RX

350 AWD

46,641 miles

$37,997

Fair Deal
Store transfer to Irvine, CA
2,042 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
46,641
Stock number:
27918886
VIN:
2T2HZMDA7MC287301

2022 Lexus RX 350 AWD

2022 Lexus RX

350 AWD

33,647 miles

$42,097

Fair Deal
Store transfer to Irvine, CA
223 mi away • Price includes $99 shipping Price includes $99 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
33,647
Stock number:
27946337
VIN:
2T2HZMDA1NC323677

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

52,251 miles

$30,796

Great Deal
Carson, CA
28 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
52,251
Stock number:
7P659
VIN:
2T2AZMAAXMC196027

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

68,283 miles

$33,147

Fair Deal
Store transfer to Irvine, CA
357 mi away • Price includes $149 shipping Price includes $149 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
68,283
Stock number:
28087728
VIN:
2T2HZMAAXMC189187

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

22,514 miles

$34,488

Great Deal
Laguna Niguel, CA
12 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
22,514
Stock number:
H202554
VIN:
2T2AZMAAXMC202554

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

57,001 miles

$32,595

Good Deal
Lomita, CA
31 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
57,001
Stock number:
CGSP16440
VIN:
2T2HZMAA1MC192592

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

24,896 miles

$38,488

Fair Deal
Los Angeles, CA
36 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
24,896
Stock number:
2N16807B
VIN:
2T2HZMAA1NC249746

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Luxury AWD

14,298 miles

$45,300

Great Deal
Santa Monica, CA
46 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Peppercorn
Transmission:
8-Speed Automatic
Mileage:
14,298
Stock number:
L030620
VIN:
2T2BAMCA6PC030620

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350L FWD

83,788 miles

$29,990

Good Deal
Costa Mesa, CA
8 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
83,788
Stock number:
B12310
VIN:
JTJHZKEA2M2019131

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium FWD

27,260 miles

$40,800

Good Deal
Santa Monica, CA
46 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
27,260
Stock number:
L014618
VIN:
2T2BAMBA3PC014618

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

28,863 miles

$34,650

Great Deal
Garden Grove, CA
11 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
28,863
Stock number:
MC182390P
VIN:
2T2AZMAA3MC182390

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium FWD

31,692 miles

$42,990

Good Deal
Santa Monica, CA
46 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Palomino
Transmission:
8-Speed Automatic
Mileage:
31,692
Stock number:
TC116561A
VIN:
JTJCHMAA6P2000441

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

55,920 miles

$32,200

Good Deal
Tustin, CA
3 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nori Green Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
55,920
Stock number:
MC189189
VIN:
2T2HZMAA3MC189189

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

41,500 miles

$33,851

Good Deal
Certified Pre-Owned
Cerritos, CA
21 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
41,500
Stock number:
MC184810
VIN:
2T2HZMAA0MC184810

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Luxury FWD

14,975 miles

$48,988

Good Deal
Certified Pre-Owned
Glendale, CA
40 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Peppercorn
Transmission:
8-Speed Automatic
Mileage:
14,975
Stock number:
T36295
VIN:
2T2BAMBA1PC006081

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

59,285 miles

$34,188

Fair Deal
Gardena, CA
33 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
59,285
Stock number:
00P12781
VIN:
2T2AZMAA2NC240622

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / California
  6. / Irvine
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX

Summary

  • With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
  • 84.2% of 2022 RX models on CarGurus are accident free.
  • The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Irvine, CA?

The average 2022 Lexus RX costs about $40,067.45. The average price has decreased by -4.8% since last year. The 184 for sale near Irvine, CA on CarGurus, range from $26,998 to $58,859 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Irvine, CA have no reported accidents or damage?

182 out of 184 for sale near Irvine, CA have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Irvine CA

  • 2024 Lexus RX in Irvine CA

  • 2023 Lexus RX in Irvine CA

  • 2021 Lexus RX

  • 2020 Lexus RX

  • 2019 Lexus RX in Irvine CA

  • Lexus RX 350 FWD

  • Lexus RX 350 AWD

  • Lexus RX 350 F Sport AWD

  • Lexus RX 350 F Sport Handling AWD

  • Lexus RX 350L AWD

  • Lexus RX 350L FWD

  • Lexus RX 350 F Sport FWD

  • Lexus RX 350L Luxury AWD

  • Lexus RX 350L Luxury FWD

  • Lexus RX 350 F Sport Series 3 AWD in Irvine CA

  • 2022 Lexus RX in Pomona CA

  • 2022 Lexus RX in Los Angeles CA

  • 2022 Lexus RX in Victorville CA

  • 2022 Lexus RX in Lancaster CA

  • Lexus RX in Irvine CA

  • Lexus SUVs & Crossovers for Sale in Irvine CA

  • Popular Celebrity Cars for Sale in Irvine CA

  • Reliable Cars For Sale in Irvine CA

  • Lexus Coupes for Sale Near Irvine CA

  • Affordable Luxury Cars For Sale in Irvine CA

  • Used Luxury Cars for Sale in Irvine CA

  • All Used Cars

  • Manual Transmission Cars

  • Luxury Cars

  • Cars with Red Interior

  • Cheap Manual Cars

  • Hybrid Cars

  • Sports Cars

  • Electric SUVs

  • Cheap Trucks

  • Small Cars

  • Third Row SUVs

  • Three Quarter Ton Trucks

  • Lifted Trucks

  • Manual Transmission Trucks

  • Diesel Trucks

  • Hybrid SUVs

  • Dually Trucks

  • One Ton Trucks

  • Cheap SUVs

  • Lifted Ford Trucks

  • 4x4 Trucks

  • Work Trucks

  • AWD SUVs

  • Ford Trucks

  • Chevrolet Trucks

  • Toyota Trucks

  • Trucks Under $10,000

  • Cars Under $15,000

  • Sports Cars Under $20,000

  • Trucks Under $20,000

  • Used Sedans for Sale with Low Mileage

  • Used SUVs / Crossovers for Sale with Low Mileage

  • Used Hatchbacks for Sale with Low Mileage

  • Used Convertibles for Sale with Low Mileage

  • Used Vans for Sale with Low Mileage

  • Used Minivans for Sale with Low Mileage

  • Used Pickup Trucks for Sale with Low Mileage

  • Used Coupes for Sale with Low Mileage

  • Used Wagons for Sale with Low Mileage

  • Lexus of Cerritos

  • Newport Lexus

  • Temecula Valley Lexus

  • Lexus of Westminster

  • Lexus of Glendale

  • South County Lexus

  • Lexus Carlsbad

  • Longo Lexus

  • Tustin Lexus

Connect with us
Download our app
Download on the App Store Get it on Google Play
  • Company
  • About CarGurus
  • Our team
  • Press
  • Investor relations
  • Price trends
  • Careers
  • Advertise with CarGurus
  • For dealers
  • Dealer signup
  • Dealer resources
  • Terms
  • Terms of use
  • Privacy policy
  • Interest-based ads
  • Security
  • Help
  • Help center
  • Contact us
Click for the BBB Business Review of this Auto Listing Service in Cambridge MA
    • United States (EN)
    • Estados Unidos (ES)
    • Canada (EN)
    • Canada (FR)
    • United Kingdom

© 2026 CarGurus, Inc., All Rights Reserved.